转化医学与肿瘤诊治

转化医学是促进基础研究成果向临床应用转化和根据临床医学的需求从事应用基础研究的桥梁。本文以转化医学在肿瘤防治研究的实例,分析转化医学的意义,以期为使大家重视转化医学,提高肿瘤诊治水平。     

DESIRE AND RESPONSIBILITY: THE ETHICS OF COUNTERTRANSFERENCE EXPERIENCE

The analyst's desire expressed in impactful wishes and intentions is foundational to countertransference experience, yet undertheorized in the literature. The “wider” countertransference view, associated with neo‐Kleinian theory, obscures the nature of countertransference and the analyst's contribution to it. A systematic analysis of the logic of desire as an intentional mental state is presented. Racker's (1957) talion law and Lacan's (1992) theory of the dual relation illustrate the problems that obtain with a wholesale embrace of the wider countertransference perspective. The ethical burden placed on the analyst in light of the role played by desire in countertransference is substantial. Lacan's ethics of desire and Benjamin's (2004) concept of the moral third are discussed.     

孔门三弟子比较论说

孔门十哲,出类拔萃者莫若颜回、子贡、子路,且此三人之身世、性情、才具、道德修为和成就各有风华,但又殊途同归：共同维护了孔门。光大了儒家。孔子称得上是中华民族几千年来最为伟大的教育家,颜回、子贡、子路三人各方面的修为和成就,莫不大大受惠于夫子有教无类、因材施教的卓越的教育理论和教育方式。三人也没有辜负孔子的教导,以身垂范,较好地诠释了孔子儒家所宣扬的“仁、智、勇”;并与其师一道,在乱世中矢志不渝,坚守道义,追求理想,为儒学的传播和繁荣做出了重要的贡献。     

情绪作为道德判断的“催化剂”：道德判断中的评价倾向与特异性效应

在不同领域的道德判断中,情绪可能起着“催化剂”的作用。一种特定情绪对应一种核心评价;一种情绪只影响某一道德领域的判断,不同情绪的影响是特异性的;进化心理学和具身认知对道德判断中存在的评价倾向和特异性效应进行了解释。未来研究需要探索评价倾向与特异性效应的内在心理机制。以及进一步探讨文化等第三变量对不同情绪与特定领域道德判断的影响。     

Evaluating the effect of educational media exposure on aggression in early childhood

Preschool-aged children (M = 42.44 months-old, SD = 8.02) participated in a short-term longitudinal study investigating the effect of educational media exposure on social development (i.e., aggression and prosocial behavior) using multiple informants and methods. As predicted, educational media exposure significantly predicted increases in both observed and teacher reported relational aggression across time. Follow-up analyses showed that educational media exposure also significantly predicted increases in parent reported relational aggression across more than a two year period. Results replicate and extend prior research that has demonstrated links between educational media exposure and relational aggression, but not physical aggression, during early childhood.     

Administering Quantitative Instruments With Qualitative Interviews: A Mixed Research Approach

The authors demonstrate how collecting quantitative data via psychometrically sound quantitative instruments during the qualitative interview process enhances interpretations by helping researchers better contextualize qualitative findings, specifically through qualitative dominant crossover mixed analyses. They provide an example of this strategy, whereby a baseline was established using a quantitative scale and normative data to help interpret qualitative interviews, resulting in what they call a mixed methods interview. Philosophical and practical implications are discussed.     

Environmental Influences on Ethical Decision Making: Climate and Environmental Predictors of Research Integrity

It is commonly held that early career experiences influence ethical behavior. One way early career experiences might operate is to influence the decisions people make when presented with problems that raise ethical concerns. To test this proposition, 102 first-year doctoral students were asked to complete a series of measures examining ethical decision making along with a series of measures examining environmental experiences and climate perceptions. Factoring of the environmental measure yielded five dimensions: professional leadership, poor coping, lack of rewards, limited competitive pressure, and poor career direction. Factoring of the climate inventory yielded four dimensions: equity, interpersonal conflict, occupational engagement, and work commitment. When these dimensions were used to predict performance on the ethical decision-making task, it was found that the environmental dimensions were better predictors than the climate dimensions. The implications of these findings for research on ethical conduct are discussed.     

Deception in Experiments: Revisiting the Arguments in Its Defense

In psychology, deception is commonly used to increase experimental control. Yet, its use has provoked concerns that it raises participants' suspicions, prompts second-guessing of experimenters' true intentions, and ultimately distorts behavior and endangers the control it is meant to achieve. Over time, these concerns regarding the methodological costs of the use of deception have been subjected to empirical analysis. We review the evidence stemming from these studies.     

Moral Virtue and Practical Wisdom: Theme Comprehension in Children,Youth, and Adults

The authors tested 3 hypotheses about the relation of moral comprehension to prudential comprehension by contrasting comprehension of themes in moral stories with comprehension of themes in prudential stories among third-grade, fifth-grade, and college students (n = 168) in Study 1, and among college students, young and middle-aged adults, and older adults (n = 96) in Study 2. In both studies, all groups were statistically significantly better at moral theme comprehension than prudential theme comprehension, suggesting that moral comprehension may develop prior to prudential comprehension. In Study 2, all groups performed equally on moral theme generation whereas both adult groups were significantly better than college students on prudential theme generation. Overall, the findings of these studies provide modest evidence that moral and prudential comprehension each develop separately, and that the latter may develop more slowly.     

Tuberculosis detection by giant african pouched rats

In recent years, operant discrimination training procedures have been used to teach giant African pouched rats to detect tuberculosis (TB) in human sputum samples. This article summarizes how the rats are trained and used operationally, as well as their performance in studies published to date. Available data suggest that pouched rats, which can evaluate many samples quickly, are sufficiently accurate in detecting TB to merit further investigation as a diagnostic tool.