传染病大暴发期间的临床研究：理论合理性和实践可行性

试图从治疗和研究在伦理基础及政策导向上的差异入手,分析在流行病大暴发期间扩大临床试验性治疗和缩短研究进程等策略的不足,指出其局限性及不可行性;阐明知情同意的伦理原则和预警的监管原则是衡量临床研究规范化和安全性的基准。论文得出结论,阶梯式群试验是流行病大暴发期间较为合宜的研究性治疗策略,它可以确保知情同意的伦理原则和预警的监管原则在不动摇的前提下,使研究性治疗及时为患者所得。     

仁与天理通而为一视域下的程颢易学

置身由汉唐经学向宋明理学转型过程中的程颢,对易学的天人之学作出了创造性诠释与转化,建构起仁与天理通而为一视域下的崭新易学天人之学,推出了他的理学体系。程颢的易学,首先开示了一个充满盎然生机、生意的有机整体宇宙图景,继之揭示了此一生机、生意之所自来的终极宇宙根基、根据,即天理,并指出天理是一终极的令物生生之理,即是一最高的绝对之善本身,由此天理即仁体。天理与仁通而为一,可名之日天理—仁体。此一天理—仁体令天地万物涵具并彰显出盎然生机、生意,且一体无隔。人禀受它而具备了存在的所以然的终极宇宙根基和充足的价值根据与资源,应据之一则珍视自己生命的内在价值,令其原发性畅然舒展、展现与实现,再则珍视并善待他人他物的内在价值,视天地人物一体无隔的有机宇宙整体中的一切皆为我生命的有机组成部分,期其亦皆能原发性畅然舒展、展现与实现自我,从而成就起一宇宙式大我,达到成为天理—仁体自觉圆融化身的最高的生命境界,即天地境界。为此,尚需作识仁与定性的工夫。     

The predictive accuracy of intertemporal‐choice models

How do people choose between a smaller reward available sooner and a larger reward available later? Past research has evaluated models of intertemporal choice by measuring goodness of fit or identifying which decision‐making anomalies they can accommodate. An alternative criterion for model quality, which is partly antithetical to these standard criteria, is predictive accuracy. We used cross‐validation to examine how well 10 models of intertemporal choice could predict behaviour in a 100‐trial binary‐decision task. Many models achieved the apparent ceiling of 85% accuracy, even with smaller training sets. When noise was added to the training set, however, a simple logistic‐regression model we call the difference model performed particularly well. In many situations, between‐model differences in predictive accuracy may be small, contrary to long‐standing controversy over the modelling question in research on intertemporal choice, but the simplicity and robustness of the difference model recommend it to future use.     

Processing ambiguous Spanish se in a minimal chain

The recovery of pieces of information that are not linguistically expressed is a constant feature of the process of language comprehension. In the processing literature, such missing information is generally referred to as “gaps”. Usually, one resolves gaps by finding “fillers” in either the sentence or the context. For instance, in Peter seemed to be upset, Peter is really the subject of being upset but appears as surface subject of seems. Sometimes constituents move, leaving gaps behind. Various Romance languages such as Spanish or Italian have a grammatical particle se/si, which, as it is extremely ambiguous, licenses different sorts of gaps. In Spanish, se can encode at least reflexive, impersonal, and passive meanings. In an eye-tracking experiment we contrast reflexive structures containing postverbal subjects with impersonal structures with no subjects (GAP se vendó apresuradamente el corredor/“the runner bandaged himself hurriedly” vs. GAP se vendó apresuradamente al corridor/“(someone) bandaged the runner hurriedly”). In a second manipulation we contrast the presence of an extra argument with se-passives (GAP se vendó el tobillo el corredor/“the runner bandaged his ankle” vs. GAP se vendó el tobillo al corridor/“the runner's ankle was bandaged”). Our comparisons involve contrasting standard transitive structures with nonstandard word order (postverbal subject and a preverbal subject gap) against inherently complex and less habitual structures such as impersonals (with no subject) or se-passives (with subjects in canonical object position). We evaluate the minimal chain principle (de Vincenzi, 1991 De Vincenzi, M. 1991. Syntactic parsing strategies in Italian, Dordrecht, , The Netherlands: Kluwer. [Crossref] , [Google Scholar]), according to which displacement is costly because it entails complex (derivational) “chains” that must be undone before phrasal packaging can commence. We show the minimal chain principle to be essentially correct when contrasting more complex but more frequent structures with less complex but less frequent structures. A noteworthy feature of this research is that the gaps appear before the fillers in the structures that we analyse.     

Movements or targets: What makes an action in action–effect learning?

According to ideomotor theory, actions become linked to the sensory feedback they contingently produce, so that anticipating the feedback automatically evokes the action it typically results from. Numerous recent studies have provided evidence in favour of such action–effect learning but left an important issue unresolved. It remains unspecified to what extent action–effect learning is based on associating effect-representations to representations of the performed movements or to representations of the targets at which the behaviour aimed at. Two experiments were designed to clarify this issue. In an acquisition phase, participants learned the contingency between key presses and effect tones. In a following test phase, key–effect and movement–effect relations were orthogonally assessed by changing the hand–key mapping for one half of the participants. Experiment 1 showed precedence for target–effect over movement–effect learning in a forced-choice RT task. In Experiment 2, target–effect learning was also shown to influence the outcome of response selection in a free-choice task. Altogether, the data indicate that both movement–effect and target–effect associations contribute to the formation of action–effect linkages—provided that movements and targets are likewise contingently related to the effects.     

论罗尔斯的政治义务理论

政治义务是政治哲学的核心问题。哈特首先用“相互限制原则”来解释政治义务,这一原则为罗尔斯所继承并加以修正。鉴于该原则存在的诸多问题,罗尔斯在《正义论》中削减了它在政治义务的道德证明中的作用,而诉诸正义的自然责任原则。这个原则仍然受到来自多方面的批评,许多罗尔斯的追随者对这些批评作了回应。罗尔斯从公平游戏原则到自然责任原则的转变反映了他对契约论不同的态度。