胰岛再生治疗的前景

胰岛β细胞数量减少和功能障碍是糖尿病的根本原因,现有的治疗手段主要以维持正常血糖水平为主要目的,尚无有效恢复受损胰岛功能的治愈性治疗手段。胰岛再生治疗将是一种可以恢复受损胰岛功能、改变糖尿病自然病程的崭新治疗手段。目前现有的噻唑烷二酮、肠促胰岛素及类似物、二肽基肽酶-4抑制剂等治疗,虽然不是一类新的胰岛再生药物,但其具有一定的促进胰岛再生、改善胰岛功能的作用。体外诱导β细胞再生也将为胰岛移植提供新的来源,为治愈糖尿病带来曙光。     

大连地区健康人群体重指数分布状况的调查分析

调查分析大连地区健康人群中体重指数(BMI)、腰臀围比(WHR)的分布状况。对630例长期居住大连地区的21岁～60岁汉族健康成人的BMI、WHR进行调查分析,检测受检者身高、体重、腰围、臀围,按不同年龄段、不同性别分析BMI、WHR的性别及年龄分布。大连地区健康人群总体的平均BMI为(23.66±3.12)kg/m~2,其中男性为(24.66±2.88)kg/m~2。女性为(22.41±2.97)kg/m~2,经t检验有显著差异(t=11.85,P＜0.001)。BMI≥25的人群比例为24.1%,BMI≥30的为3.0%。BMI随年龄变化的曲线为斜线,从21岁～60岁,随着年龄的增长而显著升高,51岁～60岁达到最高峰;WHR随年龄变化的曲线为斜线,随着年龄的增长而显著升高,51岁～60岁达到最高峰。随着社会生活水平的提高,人群中BMI、WHR结构发生了明显的变化,肥胖者日趋增多,应重视超重和肥胖的防治工作。     

Can we still stand by words? or: Why rhetoric needs A pragmatic turn

Rhetorical theory has developed powerful criticisms of pretentions to objectivity, in the spirit of deconstruction and ideology critique. These critiques contain nihilistic tendencies when they become abstracted from the interactive social contexts upon which they depend for their own significance and efficacy. With a rich analysis of the social bases of communication sustained by its commitment to the project of deliberative democracy, the classic Pragmatism of John Dewey and G. H. Mead can provide an important corrective by orienting rhetorical theory toward reflective social-political engagement.     

Self-reported change in health behaviour after a mass media-based health education campaign

A comprehensive short-term fund-raising campaign, was launched in 1987 by a health charity organization in cooperation with the only Norwegian TV-channel covering the whole country. The campaign which was extensively announced on TV and other media and which involved large proportions of the population, finished up with a six hour TV-show on the fund-raising day. Because a considerable amount of information on prevention of heart disease was presented in connection with the campaign, it is presently evaluated as a nationwide health education campaign. Twenty-two per cent of the population reported changes in one or more habits in connection with the campaign (one third of them took more exercise, while one quarter reduced/quit their smoking). Health behaviour change among family/friends, reported new knowledge of health and worry created by the campaign, were the factors most clearly associated with self-reported behaviour change. The paper discusses the magnitude of the effects of the campaign in relation to the study design, and the importance of social environment and fear arousal on health behaviour.     

Mental Health and Incarcerated Youth. II: Service Utilization

The incarceration of mentally ill youth is a serious problem not receiving the same attention as in adults. In this study, we examine the level of prior service utilization in incarcerated youth versus youth receiving community mental health services. We randomly recruited youth from middle South Carolina served by a local community mental health center (CMHC; n = 60), hospitalized in the state adolescent inpatient program (n = 50), and incarcerated in the S.C. Dept. of Juvenile Justice facilities (n = 75). We used a Services History to evaluate episodes of prior utilization of mental health, social service, educational, residential, and volunteer services, as well as the DISC-PC 2.3 to evaluate DSM-III-R diagnoses and symptoms and the CBCL and YSR to evaluate behavioral symptomatology. Incarcerated, hospitalized, and CMHC youth utilized similar levels of educational services and social services. Incarcerated youth had a significantly lower lifetime utilization of outpatient and acute mental health services and significantly higher utilization of out-of-home residential services than the other groups. These services utilization variables, along with gender and age, significantly distinguish incarcerated youth from the clinical groups, with clinical variables not serving to significantly distinguish them. Our results indicate the need to develop programs to prevent the entry of mentally ill/emotionally disturbed youth into the juvenile justice system. Youth who are at risk for incarcenation may benefit from intensive mental health services to prevent out-of-home placement and later incarceration.     

Computing the COM from the COP in postural sway movements

A method is described for computing the centre of mass (COM) from empirical estimates of the centre of pressure (COP) obtained by means of a force platform. The method is based on a biomechanical model of sway movements in quiet standing, according to which the horizontal acceleration of the COM is approximately proportional to the COM–COP difference. The equations are solved by approximating the solution with best fitting spline functions. The implications for movement control are discussed.     

群体心理现象——一种后现代的公共精神卫生问题

探讨以群体心理为基础的公共精神卫生问题的概念、重要性,以及发生的病理机制。认为当代公共精神卫生问题所具有定性模糊、文化边缘化等后现代的特点都与群体非理性心理的性质有关。     

A predictive model for psychological reactions to crime in Italy: an analysis of fear of crime and concern about crime as a social problem

In this study a model for predicting fear of crime (FC) and concern about crime as a social problem (CC) in Italy has been built, using three sets of independent variables concerning: (a) the sociodemographic and criminal victimization domain; (b) the psychosocial domain; and (c) the mass media. A secondary analysis on data gathered by the Observatory of the North‐West (N = 3262, a mail panel that is representative of the Italian population over 18) has been performed. Results showed that FC and CC are related yet distinct constructs: FC is less widespread than CC, and has different predictors. FC predictors are sociodemographic, psychosocial and, above all, victimization variables; whereas mass media and psychosocial variables predict CC. Results were compared with the literature on the topic. Implications, limitations, and future directions are discussed. Copyright © 2004 John Wiley & Sons, Ltd.     

Development of visual center of mass localization for grasp point selection

Adults assess precisely the center of mass (CM) of single-bodied objects and choose grasping points that span an axis through or close to the center of mass when lifting them. The present study examined how children and adults assess the CM when lifting two-bodied objects (barbells) and how this ability develops. Four- to five-year olds, 6- to 7-year olds, 9- to 11-year olds and adults were required to grasp and lift symmetrically and asymmetrically proportioned miniature barbells and their grasping points were recorded. While the 4- to 5-year olds grasped near the center of the barbell, accuracy of assessing the correct CM improved linearly with age. Although adults grasped close to the CM, their CM determination follows only an approximation of the physical law.     

Perceptions of female body weight and shape among indigenous and urban Europeans

Two important cues to female physical attractiveness are body mass index (BMI) and body shape as measured by the waist-to-hip ratio (WHR). This study examined the relative contribution of both cues in three culturally distinct populations. A total of 119 Finnish, Sámi and British male observers rated a set of un-edited photographs of women with known BMI and WHR. The results showed that there were significant differences in preferences for physical attractiveness, with the indigenous Sámi preferring figures with larger BMIs and more tolerant of heavyweight figures than either Finnish participants in Helsinki or Britons in London, who were indistinguishable in their preferences for slim figures. The findings are discussed in terms of evolutionary psychological explanations of mate selection, and sociocultural theories which emphasizes the learning of preferences for body sizes in social and cultural contexts.