创伤后心理复原的生理机制

心理复原是个体在经历对生命具有威胁的事件或严重的创伤后仍然能回复到良好适应状况的现象。对心理复原生理机制的研究存在两种研究取向：或从个人能力的角度,或从发展结果的角度。创伤记忆的抑制、大脑的可塑性、神经生物的调节以及基因、气质、情绪调节、认知过程、早期经验等保护因子的影响机制是研究的主要内容。文章最后对今后的研究进行了展望     

灾难中的心理危机干预——精神病学的视角

灾难事件是一种特殊类型的生活事件,因其超出个体应对能力,因此灾难事件后常并发一系列的精神卫生问题。急性应激障碍、创伤后应激障碍、抑郁症、自杀是灾后常见精神卫生问题。本文回顾了近年来灾难事件相关精神障碍的研究,并总结了去年发生在我国的两次重大灾难性事件的相关研究结果,从精神病学视角对灾难事件后心理危机干预策略进行了探讨。     

保留的跨通道启动与老化：对于近期观点的总结

通道内重复启动的研究提示老年人内隐记忆未受损, 这不只体现在视觉通道上还包括其他感觉通道(例如触觉、听觉和嗅觉)。然而很少有研究考察启动任务是否具有通道特异性。在以年轻人为被试的研究中发现跨通道迁移(视觉到触觉和触觉到视觉)和通道内迁移(视觉到视觉, 触觉到触觉)具有相似性。一项最近的研究进一步探索老年人在跨通道启动任务上是否受损。结果显示视觉和触觉间的跨通道启动在年轻被试和老年被试上都是保留的且具有对称性。并且, 对于自然声响、图片的通道内和跨通道启动任务随着年老化发展仍旧保留。这些行为结果和其它最近神经科学结果显示跨通道启动发生于枕叶后纹状皮层区, 而这一区域在老年人中未损坏。这一领域未来的研究方向包括利用不同知觉通道间、利用熟悉的和新异的刺激并结合行为的和脑成像的方法, 通过设计完善的跨通道启动来研究正常老人与阿尔兹海默病人, 还包括将设计得完善的启动任务包括在用于改善老年人记忆功能的项目中。     

Diagnostic Discrimination of Patients with Different OCD Main Symptom Domains from each Other and from Anxious and Depressive Controls

The extent to which the subscales of multidimensional OCD measures accurately distinguish patients with specific OCD main symptom domains from controls at different cutscores has not yet been examined. Diagnostic accuracy of OCD measures usually is determined by comparing the total scores of heterogeneous OCD samples and controls and therefore may underestimate the measures’ discrimination potential. In the current study, subtype-specific diagnostic accuracy and criterion-related validity of the Obsessive-Compulsive Inventory-Revised (OCI-R) subscales were examined in 327 patients with OCD, anxiety, and/or depressive disorders. All subscales demonstrated good to excellent criterion-related validity and diagnostic accuracy for distinguishing patients with specific OCD main symptom domains from controls. As expected, the single OCI-R subscales lead to more accurate diagnostic decisions than the total scale. Thus, the subscale-specific cutscores significantly improve the OCI-R’s utility for subtype-specific treatment planning and outcome measurement. Furthermore, an alternative classification algorithm distinguishing patients with OCD from controls based on subscale cutscores leads to a better sensitivity, but also to a lower specificity than discrimination based on the total scale cutscore.     

A meta‐analysis of psychopathy‐, antisocial PD‐ and FFM associations

This research meta‐analytically summarizes the relationships of the Five‐Factor Model (FFM) with psychopathy and Antisocial Personality Disorder (APD). Effect sizes of the associations between psychopathy, APD and the FFM were compiled from 26 independent samples (N = 6913) for psychopathy and 57 independent samples (N = 16 424) for APD. The results revealed predominantly points of similarity and some differences in the FFM associations of both disorders. Symptoms of psychopathy and APD were negatively associated with Conscientiousness and Agreeableness facets and positively with scores on Angry–Hostility (N2), Impulsiveness (N5), Excitement Seeking (E5) and negatively with Warmth (E1). Only psychopathy had a small negative association with Anxiety (N1) and was characterized by stronger negative associations with Agreeableness and Straightforwardness (A2), Compliance (A4) and Modesty (A5) compared to APD. The moderator analyses showed that sample type, use of the NEO‐PI‐R and APD instrument moderated the APD FFM associations, while psychopathy instrument and age group were moderators in the psychopathy MA. Implications of this research for the assessment of APD and psychopathy relying on dimensional models of personality pathology are discussed. Copyright © 2009 John Wiley & Sons, Ltd.     

Stability and Change in Personality Disorder

ABSTRACT— The standard view of personality disorder is that it is a maladaptive expression of personality traits, which are relatively stable and unchanging. Thus, personality disorder has been considered to have its roots in childhood and adolescence, to persist in adulthood, and to be difficult to change. However, recent research has challenged this view, revealing that personality continues to change, albeit more slowly, well into adulthood, and that the maladaptive manifestations of personality disorder are much less stable than previously believed. These research findings are described, and factors that influence stability and change in personality disorder are discussed. The emerging view of personality disorder has important implications for diagnosis, assessment, and treatment of personality pathology.     

Emotionally controlled decision-making and a gene variant related to serotonin synthesis in women with borderline personality disorder

The Iowa Gambling Task (IGT) was used to examine (i) social decision-making in women with borderline personality disorder (BPD), and (ii) the relationship between impaired decision-making and the tryptophan hydroxylase-1 (TPH-1) gene, involved in serotonin synthesis. Forty-two women with BPD and a history of suicide attempts were genotyped, and the frequency of a TPH-1 haplotype previously uniquely associated with BPD was calculated. The BPD group scored significantly lower than a control group in the IGT. Furthermore, the TPH-1 haplotype displayed a significantly higher frequency in BPD participants with impaired decision making, compared to BPD participants with normal scores. These findings suggest that impaired decision-making as determined by the IGT is a feature of BPD and may be (i) associated with serotonin dysfunction, and (ii) possibly relevant for suicidal behavior.     

Assessment of self-conscious emotions: a Swedish psychometric and structure evaluation of the Test of Self-Conscious Affect (TOSCA)

The Test of Self-Conscious Affect (TOSCA) is a well-established scenario-based questionnaire assessing self-conscious emotions, such as shame and guilt, which have been shown to be differentially associated with a variety of functional, motivational, behavioral and health outcomes. The aim of this study was to evaluate the psychometric properties and internal structure of a Swedish version of TOSCA in a sample of 361 healthy adults. The psychometric properties and internal consistency of the Swedish version were at level with the original US TOSCA version for shame, guilt and detachment. The internal structure of the Swedish version was acceptable for shame, guilt and detachment but contained shortcomings in assessment of externalization.