听觉障碍人群的言语机制

对听觉障碍人群言语机制的研究,提供了独特的视角来探讨人脑内语言专门化系统的组织。该回顾了近年来在该领域内进行的损伤研究及功能性成像研究,着重综述了三个问题：(1)左右半球损伤造成的手语失语症的特点;(2)手语加工过程中左右半球的激活模式;(3)先天聋被试在阅读唇语过程中的脑内激活模式及后部扣带皮层在唇语阅读过程中的可能作用。     

Race, Behavior, and the Brain: The Role of Neuroimaging in Understanding Complex Social Behaviors

Recent advances in brain imaging techniques have allowed us to explore the neural basis of complex human behaviors with more precision than was previously possible. As we begin to uncover the neural systems of behaviors that are socially and culturally important, we need to be clear about how to integrate this new approach with our psychological understanding of these behaviors. This article reviews findings about the neural systems involved in processing race group information, in particular the recognition of same-race versus other-race faces and the explicit and implicit evaluation of race groups. Combining the psychological and neural approaches can advance our understanding of these complex human behaviors more rapidly and with more clarity than could be achieved with either approach alone. However, it is inappropriate to assume that the results of neuroimaging studies of a given behavior are more informative than the results of psychological studies of that behavior.     

从使动句加工的功能性磁共振成像看中文句法加工的独立性

大脑中的句法加工模式是神经认知科学研究的重要课题, 而句法加工是否存在独立性一直是研究者争论较多的问题。有形态标记的英语等印欧语语言的句法可以通过形态变化表现, 而汉语不具备与印欧语有明确对应关系的形态变化, 因此汉语的句法变化几乎不能通过外在形态标记。通过3T场强功能性磁共振成像, 以汉语语义等值使动句为研究材料, 对不依赖形态变化来标记句法变化的汉语句法加工的独立性进行了初步研究。结果显示, 大脑左侧额叶对于汉语句法加工具有重要的作用, 尤其是大脑左侧额叶中回的BA44区和额叶下回的BA47区都对汉语句法加工较为敏感, 这表明即使不通过形态改变来标记句法变化, 汉语句子加工中的句法加工仍然可以被分离, 句法独立性的加工主要由大脑左侧额叶中回及大脑左侧额叶下回等脑区承担, 大脑左侧颞叶并未参与汉语句法的独立性加工。     

抑郁症的影像遗传学研究:探索基因与环境的交互作用

抑郁症具有中等的遗传度。通过影像遗传学方法探讨抑郁相关基因的多态性对神经活动的影响,发现编码五羟色胺、促肾上腺素释放激素受体、多巴胺等神经递质或受体的基因多态性会影响杏仁核、前扣带等情绪加工脑区的功能或结构,且多数基因与压力生活经历发生交互作用。表明基因与环境的交互作用在抑郁症发病机理中扮演重要角色。未来的研究应拓展遗传和神经影像分析方法,重视环境因素的测量,通过整合遗传、神经影像及环境变量构建抑郁病理模型。     

动允直接知觉的共鸣原理

传统认知理论认为我们只能间接知觉动允,而生态认知心理学则认为对动允的知觉是个体与环境信息直接共鸣的过程。生态认知心理学首先判定动允并不是存在于我们头脑中的认识,而是实际存在于个体-环境系统中的事实,对动允的直接知觉就是对动允的检测而非推测,是对动允信息的拾取而非对记忆内容的提取。这种直接知觉表现为身体的相关动作机制（动作神经元、肌肉组织等）与环境中动允信息的共鸣。进化与学习在共鸣的形成与发展中具有重要作用。     

Establishing motion control in children with autism and intellectual disability: Applications for anatomical and functional MRI

Excessive motion makes magnetic resonance imaging (MRI) extremely challenging among children with autism spectrum disorder (ASD). The medical risks of sedation establish the need for behavioral interventions to promote motion control among children with ASD undergoing MRI scans. We present a series of experiments aimed at establishing both tolerance of the MRI environment and a level of motion control that would be compatible with a successful MRI. During Study 1, we evaluated the effects of prompting and contingent reinforcement on compliance with a sequence of successive approximations to an MRI using a mock MRI. During Study 2, we used prompting and progressive differential reinforcement of other behaviors (DRO) to promote motion control in a mock MRI for increasing periods of time. Finally, during Study 3, some of the participants underwent a real MRI scan while a detailed in‐session motion analysis informed the quality of the images captured.     

背景性渴求与事件性渴求:区分心理渴求对尼古丁成瘾的不同作用路径

大量研究发现心理渴求机制的紊乱是尼古丁成瘾的核心机制之一。线索暴露是探索心理渴求与尼古丁成瘾关系的重要研究范式。但最近研究者提出该范式较难区分事件性渴求与背景性渴求,导致无法清楚定位渴求在尼古丁成瘾中扮演的角色。通过对以往文献的回顾,对不同成瘾概念、作用机制和生理基础进行对比分析,认为事件性渴求与背景性渴求两者在维持成瘾行为上的确存在不同的作用路径。未来研究应改进实验范式,分别探讨两种心理渴求与尼古丁成瘾的内在联系,完善心理渴求与尼古丁成瘾的关系模型,为尼古丁成瘾的治疗和干预等方法提供一定的理论依据。     

Neurophysiology and neuroanatomy of reflexive and volitional saccades: evidence from studies of humans

This review provides a summary of the contributions made by human functional neuroimaging studies to the understanding of neural correlates of saccadic control. The generation of simple visually guided saccades (redirections of gaze to a visual stimulus or pro-saccades) and more complex volitional saccades require similar basic neural circuitry with additional neural regions supporting requisite higher level processes. The saccadic system has been studied extensively in non-human (e.g., single-unit recordings) and human (e.g., lesions and neuroimaging) primates. Considerable knowledge of this system’s functional neuroanatomy makes it useful for investigating models of cognitive control. The network involved in pro-saccade generation (by definition largely exogenously-driven) includes subcortical (striatum, thalamus, superior colliculus, and cerebellar vermis) and cortical (primary visual, extrastriate, and parietal cortices, and frontal and supplementary eye fields) structures. Activation in these regions is also observed during endogenously-driven voluntary saccades (e.g., anti-saccades, ocular motor delayed response or memory saccades, predictive tracking tasks and anticipatory saccades, and saccade sequencing), all of which require complex cognitive processes like inhibition and working memory. These additional requirements are supported by changes in neural activity in basic saccade circuitry and by recruitment of additional neural regions (such as prefrontal and anterior cingulate cortices). Activity in visual cortex is modulated as a function of task demands and may predict the type of saccade to be generated, perhaps via top-down control mechanisms. Neuroimaging studies suggest two foci of activation within FEF - medial and lateral - which may correspond to volitional and reflexive demands, respectively. Future research on saccade control could usefully (i) delineate important anatomical subdivisions that underlie functional differences, (ii) evaluate functional connectivity of anatomical regions supporting saccade generation using methods such as ICA and structural equation modeling, (iii) investigate how context affects behavior and brain activity, and (iv) use multi-modal neuroimaging to maximize spatial and temporal resolution.     

Neuroimaging as a New Tool in the Toolbox of Psychological Science

ABSTRACT— During the past quarter century, advances in imaging technology have helped transform scientific fields. As important as the data made available by these new technologies have been, equally important have been the guides provided by existing theories and the converging evidence provided by other methodologies. The field of psychological science is no exception. Neuroimaging is an important new tool in the toolbox of psychological science, but it is most productive when its use is guided by psychological theories and complemented by converging methodologies including (but not limited to) lesion, electrophysiological, computational, and behavioral studies. Based on this approach, the articles in this special issue specify neural mechanisms involved in perception, attention, categorization, memory, recognition, attitudes, social cognition, language, motor coordination, emotional regulation, executive function, decision making, and depression. Understanding the contributions of individual and functionally connected brain regions to these processes benefits psychological theory by suggesting functional representations and processes, constraining these processes, producing means of falsifying hypotheses, and generating new hypotheses. From this work, a view is emerging in which psychological processes represent emergent properties of a widely distributed set of component processes.