Effects of Gradual Versus Sudden Training on the Cognitive Demand Required While Learning a Novel Locomotor Task

The cognitive demand required for a range of locomotor tasks has been described for a variety of populations. However, the effect of different training strategies on the cognitive demand required while learning novel locomotor tasks is not well understood and may inform physical rehabilitation. The authors examined whether two training strategies, gradual and sudden training, influenced the cognitive demand required while practicing a novel locomotor task, asymmetric split-belt treadmill walking. Simple reaction times and whole-body kinematics were recorded throughout practice. Gradual training resulted in significantly lower reaction times during much of training, suggesting that gradual training is less cognitively demanding than sudden training, possibly due to a reduction in error feedback or movement planning demands.     

Effects of Potential Partners' Costume and Physical Attractiveness on Sexuality and Partner Selection

Male and female college students in the United States (N = 224) viewed models who had been prerated for physical attractiveness and who were dressed in costumes representing one of three levels of socioeconomic status (SES). Subjects reported their willingness to engage with these stimulus persons in six relationships involving various levels of marital potential and sexual involvement. Models' costume status had greater effects on female subjects' willingness than on male subjects' willingness to enter all six relationships. This difference was larger when the physical attractiveness of models was low than when it was high. Costume status also affected female subjects' ratings of male models' attractiveness but did not affect male subjects' ratings of female models' attractiveness. Results supported eight hypotheses derived from evolutionary theory: In choosing partners, men and women weighed potential partners' SES and physical attractiveness differently, and these factors may have different behavioral implications depending on the degree to which sexual relations, or marital potential, or both, are involved.     

晚期非小细胞肺癌TKIs治疗：关注与思考

以表皮生长因子受体（EGFR）为靶点的酪氨酸激酶抑制剂（TKIs）对晚期非小细胞肺癌EGFR突变患者的治疗效果令人瞩目。本文分析总结近年国内外相关研究,指出低剂量TKIs的应用虽有待进一步证实,但优于标准剂量组,并从安全性、改善肿瘤血管结构和功能、与细胞毒化疗的关系三方面探讨大剂量TKIs的应用效果。进一步分析指出大剂量联合小剂量TKIs能够最大程度地防止或延迟耐药的发生,进而控制疾病的进展。从而,为晚期非小细胞肺癌EGFR突变患者的TKIs治疗选择提供参考。     

Alief——影响心血管康复的潜在心理状态

心血管康复是涉及医学评价、处方运动、心血管危险因素矫正、教育、咨询和行为干预等的长期综合治疗程序,以改善心血管病的生理和心理状态,减少再次心肌梗死和猝死的危险,控制心血管症状,稳定或逆转动脉硬化过程和改善患者的心理和职业状态。心血管康复干预具体包括药物治疗、行为干预和心理介入等治疗。其中涉及一系列的心理-行为现象及概念。最近,心理医学领域提出了介于信念和想象的状态——Alief,这一具象派状态可以很好地解释与心血管康复相关的一些心理-行为现象,本文就此作一论述。     

高压氧医学与康复医学的协同发展

随着医学理论与实践的不断创新和发展,中国也正在努力寻求一种具有中国特色的现代医学发展模式.高压氧医学与康复医学都是新兴的边缘交叉性学科,具有广阔的发展潜能和空间;然而,两者在快速发展的同时也突显了一些问题,如:后续动力不足、发展方向不明确等.本文从哲学中联系与发展的角度出发,通过机制探讨及发展趋势的分析,试图寻找两者共同发展的结合点,为推动康复医学与高压氧医学在临床工作中的继续向前发展提供一种借鉴与参考.     

Science-Based Neurorehabilitation: Recommendations for Neurorehabilitation From Basic Science

ABSTRACT

Neuroscience has fundamentally changed the understanding of learning and memory within recent years. Here, the authors discuss a number of specific areas where they believe new understanding of the CNS from basic science is having a fundamental impact on neurorehabilitation and is leading to new therapeutic approaches. These areas have constituted a basis for development of some basic principles for neurorehabilitation: Optimal rehabilitation should involve (a) active (patient) participation in the training, (b) training that does not only involve many repetitions, but also continues to challenge the skill of the training person, (c) motivation and reward, (d) intensive training and practice over a long time, (e) careful organization of the training in relation to other activities, and (f) incorporation of other potentially beneficial parameters such as sleep and diet. It should in this relation also be pointed out that albeit neurorehabilitation may be predicted to have the most optimal effect early in life and as soon after injury as possible, there is no reason to believe that beneficial effects of training may not be obtained late in life or several years after injury.     

A Fully Automated,Quantitative Test of Upper Limb Function

ABSTRACT. The Rehabilitation Joystick for Computerized Exercise (ReJoyce, Rehabtronics Inc., Edmonton, Alberta, Canada), is a workstation on which participants exercise dexterous movement tasks in the guise of computer games. The system incorporates the ReJoyce Arm and Hand Function Test (RAHFT). Here the authors evaluate the RAHFT against the Action Research Arm Test (ARAT) and the Fugl-Meyer Assessment (FMA). All 3 tests were performed in 36 separate sessions in 13 tetraplegic individuals. Concurrent and criterion validities of the RAHFT were supported by a high level of correlation with the ARAT (r² = .88). Regarding responsiveness, the effect size of the RAHFT at week 6 of 1 hr/day exercise training was 1.8. Regarding reliability, the mean test–retest difference in RAHFT baseline scores was 0.67% ± 3.6%, which was not statistically significant. The RAHFT showed less ceiling effect than either ARAT or FMA. These data help validate the RAHFT as a quantitative, automated alternative to the ARAT and FMA. The RAHFT is the first comprehensive test of arm and dexterous hand function that does not depend on human judgment. It offers a standardized, quantitative outcome evaluation, which can be performed not only in the clinic, but also in the participant's home, administered by a remote therapist over the Internet.     

Rhizomatic affective spaces and the therapeutic potential of music in prison: a qualitative meta-synthesis

Research literature supports that music programmes in prisons can have a therapeutic effect in prisoners’ lives that could promote personal development and assist the process toward desistance. The authors use a meta-synthetic approach to examine 12 qualitative articles published worldwide to explore the therapeutic potential of such programmes. The findings suggest that music programmes in prison are perceived by participating prisoners as a liberating process, which encourages participation and allows for noncoercive personal development. The therapeutic potential of music programmes is located in the combination of the benefits emanating from the effect and practice of music and the creation of mental, spatial and temporal zones of free expression and those that derive from the egalitarian and nonauthoritative approach employed by the facilitators. These findings are discussed along with aspects involved in the provision of offender treatment as well as factors that affect treatment response and engagement.     

Community reintegrating former child soldiers in Northern Uganda: A qualitative study on the road to recovery

This study aimed to profile the qualities of a holistic community reintegration program for former child soldiers (FCS) in the Lira region of Northern Uganda. Informants were a convenience sample of 37 FCS (age range 17 to 34, mean age 23.86, SD = 4.715 years; females = 29.73%). FCS completed semi-structured interviews on their current living situations and existing resources. This was aimed at assessing how they were transitioning back into the community and identifying gaps in resources. About 24% of FCS reported feeling unwelcome in their communities, suggesting a need for additional support and resources through the community integration models. Thematic analysis of the data suggests that the FCS would benefit from a holistic community reintegration program with the following qualities: psychosocial support, workforce development training, and job placement. FCS emphasised the need for skills training and employment opportunities over health and wellness; suggesting that mental health support and health care are not sufficient alone for them to successfully reintegrate into the community. FCS community integration policies and practices should prioritise holistic approaches.     

Event-Based Prospective Memory in Children with Sickle Cell Disease: Effect of Cue Distinctiveness

Event-based prospective memory (EB-PM) is the formation of an intention and remembering to perform it in response to a specific event. Currently, EB-PM performance in children with sickle cell disease (SCD) is unknown. In this study, we designed a computer-based task of EB-PM; No-Stroke, Silent-Infarct, and Overt-Stroke groups performed significantly below the demographically similar control group without SCD. Cue distinctiveness was varied to determine if EB-PM could be improved. All groups, with the exception of the Overt-Stroke group, performed significantly better with a perceptually distinctive cue. Overall, these results suggest that EB-PM can be improved significantly in many children with SCD.