CHRM3基因与孤独症谱系障碍

孤独症谱系障碍是一类具有遗传基础的儿童发展障碍疾病。近些年, 研究者们从分子病理学层面发现中枢胆碱能神经系统异常与孤独症患者认知和行为异常存在相关性。尸检研究、临床案例、动物模型研究均发现毒蕈碱型(M型)乙酰胆碱受体异常和孤独症的发生有着密切的关系。在以小鼠为模型的行为学研究中, 编码毒蕈碱型乙酰胆碱受体Ⅲ亚型的CHRM3基因突变会导致小鼠出现认知障碍、刻板行为等孤独症样表现。深入了解CHRM3基因的功能将能够帮助研究者进一步解释孤独症的相关行为特征, 为孤独症儿童教育方案的制定提供新的思路和方法。     

The Orthogenetic Principle in the Perception of “Forests” and “Trees”?

This study explores possible links between ontogenetic and microgenetic change (Werner, 1948, 1957) in the perception of stimuli with multiple levels of structure. Visual search for targets defined by local versus global structure was examined in observers aged 6, 8, 10, and 22 years. Perceptual access to each level of structure was varied by using pattern elements of same (easy) or opposite contrast polarity (hard); attentional processes were isolated from sensory processes by varying the number of display items. The results showed large improvements with age in search rates for global targets, with search rates for local targets being more constant over age. This pattern held regardless of whether perceptual access to a target was easy or hard. These results support the view that the perception of local and global structure involves different underlying processes.     

说明文阅读中局部连贯因果推理的产生

探讨熟悉主题的说明文阅读过程中维持局部连贯的因果推理的产生问题。3个实验分别采用了不同的实验材料, 实验1的文本提供明确的前提信息, 实验2的材料提供隐含的前提信息, 实验3的材料在前提信息与结论信息之间插入了其他信息。总的结果表明, 熟悉主题的说明文阅读过程中, 当文本提供的前提信息与结论信息一起呈现时, 无论提供明确的还是隐含的前提信息, 实现文本局部因果连贯的推理能够即时产生; 当前提信息相隔2个句子后, 虽然读者还是可以产生因果推理检测到与推理内容矛盾的信息, 但是这种检测敏感度大有降低。基于本研究结果, 结合相关研究, 本文尝试提出关于文本阅读中推理产生的“认知代价”观, 试图整合文本推理理论。     

归类不确定情景下特征推理的综合条件概率模型

用大学生被试,通过三个实验探讨在集中呈现类别成员样本信息的归类不确定情景下的特征推理。实验结果表明,单纯的归类确定性程度和靶类别靶特征的代表性并不直接影响被试的特征推理,而是预测特征相对于目标特征的综合条件概率直接影响被试的特征推理;特征推理不是基于类别中介的间接推理,而是基于特征关联综合条件概率的直接推理。实验结果支持作者提出的预测特征综合条件概率模型。     

Workers' self‐objectification and tendencies to conform to others

Recent research showed that workers' self‐objectification—their self‐perception as objects rather than human beings—leads to detrimental intrapersonal consequences. In the present research, we explored whether this phenomenon may also affect interpersonal relations, by increasing workers' tendencies to conform. In a correlational study, Italian workers who perceived their work as more objectifying self‐objectified more—self‐attributed less human mental states and self‐perceive as more instrument‐like than human‐like—and, in turn, were more inclined to conform with others. The second study experimentally confirmed this pattern, showing that British workers who recalled an objectifying (vs. a non‐objectifying) work experience self‐objectified more. Self‐perception as instrument‐like was associated, in turn, with an increased tendency to adapt to others' opinions. The implications for organizational and social psychology are discussed.     

Sex-specific variation in facial masculinity/femininity associated with autistic traits in the general population

Reports linking prenatal testosterone exposure to autistic traits and to a masculinized face structure have motivated research investigating whether autism is associated with facial masculinization. This association has been reported with greater consistency for females than for males, in studies comparing groups with high and low levels of autistic traits. In the present study, we conducted two experiments to examine facial masculinity/femininity in 151 neurotypical adults selected for either low, mid-range, or high levels of autistic traits. In the first experiment, their three-dimensional facial photographs were subjectively rated by 41 raters for masculinity/femininity and were objectively analysed. In the second experiment, we generated 6-face composite images, which were rated by another 36 raters. Across both experiments, findings were consistent for ratings of photographs and composite images. For females, a linear relationship was observed where femininity ratings decreased as a function of higher levels of autistic traits. For males, we found a U-shaped function where males with mid-range levels of traits were rated lowest on masculinity. Objective facial analyses revealed that higher levels of autistic traits were associated with less feminine facial structures in females and less masculine structures in males. These results suggest sex-specific relationships between autistic traits and facial masculinity/femininity.     

The Role of Natural Class Features in the Acquisition of Phonotactic Regularities

Previous research has shown that phonotactic regularities can be acquired through recent production or auditory experience (e.g., Dell et  al., Journal of Experimental Psychology: Learning, Memory, and Cognition, 26(6), 1355–1367, 2000; Onishi et al., Cognition, 83(1), B13–B23, 2002). However, little is known about the role of phonological natural classes in this learning process. This study addressed this question by investigating the acquisition of a contingency relationship between onsets and medial glides by Mandarin speakers. The experiments involved the manipulation of three types of phonotactic regularities. In the Laryngeal version, onsets that preceded the same glide shared a voicing feature. In the Place version, onsets that preceded same glide shared a place feature. In the Neither version, onsets associated with the same glide shared neither a voicing feature nor a place feature. Results showed the Place version and the Laryngeal version were more easily acquired than the Neither version in terms of the amount of exposure needed to acquire the experimentally manipulated phonotactic schema and the sustainability of the acquired schema. The results suggest that the statistical learning mechanism that guides our processing of speech input prefers phonological regularities that follow certain natural class features. This preference may account for the way natural languages are structured phonologically. An erratum to this article can be found at     

Categorical structure among shared features in networks of early-learned nouns

The shared features that characterize the noun categories that young children learn first are a formative basis of the human category system. To investigate the potential categorical information contained in the features of early-learned nouns, we examine the graph-theoretic properties of noun-feature networks. The networks are built from the overlap of words normatively acquired by children prior to 2½ years of age and perceptual and conceptual (functional) features acquired from adult feature generation norms. The resulting networks have small-world structure, indicative of a high degree of feature overlap in local clusters. However, perceptual features - due to their abundance and redundancy - generate networks more robust to feature omissions, while conceptual features are more discriminating and, per feature, offer more categorical information than perceptual features. Using a network specific cluster identification algorithm (the clique percolation method) we also show that shared features among these early-learned nouns create higher-order groupings common to adult taxonomic designations. Again, perceptual and conceptual features play distinct roles among different categories, typically with perceptual features being more inclusive and conceptual features being more exclusive of category memberships. The results offer new and testable hypotheses about the role of shared features in human category knowledge.     

Nonparametric item response theory axioms and properties under nonlinearity and their exemplification with knowledge space theory

This paper investigates the dichotomous Mokken nonparametric item response theory (IRT) axioms and properties under incomparabilities among latent trait values and items. Generalized equivalents of the unidimensional nonparametric IRT axioms and properties are formulated for nonlinear (quasi-ordered) person and indicator spaces. It is shown that monotone likelihood ratio (MLR) for the total score variable and nonlinear latent trait implies stochastic ordering (SO) of the total score variable, but may fail to imply SO of the nonlinear latent trait. The reason for this and conditions under which the implication holds are specified, based on a new, simpler proof of the fact that in the unidimensional case MLR implies SO. The approach is applied in knowledge space theory (KST), a combinatorial test theory. This leads to a (tentative) Mokken-type nonparametric axiomatization in the currently parametric theory of knowledge spaces. The nonparametric axiomatization is compared with the assumptions of the parametric basic local independence model which is fundamental in KST. It is concluded that this paper may provide a first step toward a basis for a possible fusion of the two split directions of psychological test theories IRT and KST.