Who Is at Risk for Psychological Distress in Genetic Testing Programs for Hereditary Cancer Disorders?

Presymptomatic identification of disease gene carriers is becoming an increasingly common part of the clinical management of hereditary cancer disorders. With an expected increase in the number of requests for DNA testing and the limited resources for counseling, the amount of time genetic counselors are able to spend with test candidates will decrease. It is therefore important for counselors to identify persons at risk for psychological distress. Based on a review of experiences with Huntington disease and cancer patients, we describe factors likely to evoke distress in genetic cancer candidates. We also discuss the sometimes widely different ways that test candidates and their partners respond to genetic testing. By exploring risk factors for distress in relevant domains of the research, we can offer counselors guidelines for determining who may need extra counseling.     

Seek and ye shall find: test results are what you hypothesize they are

Expert clinicians were given batteries of psychodiagnostic test results (Rorschach, TAT, Draw-A-Person, Bender-Gestalt, Wechsler) to analyze. For half, a battery came along with a suggestion that the person suffers from Borderline Personality disorder, and for half, that battery was accompanied by a suggestion that he suffers from Paranoid Personality disorder. In Study 1, the suggestion was made indirectly, through a background story that preceded the test results. In Study 2, the suggestion was made directly, by the instructions given. The experts saw in the tests what they hypothesized to be there. In particular, the target diagnoses were rated higher when they were hypothesized than when they were not. Copyright © 1998 John Wiley & Sons, Ltd.     

Playful defensive responses in adult male rats depend on the status of the unfamiliar opponent

Adult male rats reared as pairmates from weaning were tested in a neutral arena with both members of another pair (one at a time). The unfamiliar pairs were found to engage in play fighting, although they were more likely to escalate the encounter into serious fighting than were pairs of familiar rats. Based on their within‐home pair behavior, each pairmate was designated as a dominant or a subordinate. When the test encounters between unfamiliar males were analyzed with regard to whether the pairings consisted of two dominants, two subordinates, or a mixed pair, the pattern of play fighting was found to be attenuated. Both dominants and subordinates were more likely to initiate playful encounters, to respond defensively during these encounters, and to do so using adult‐typical tactics of defense when paired with an unfamiliar rat that was dominant in its home cage. The mechanisms by which the home status of unfamiliar male rats can be identified by another male are discussed, particularly with regard to the role that play fighting may serve for this function. It is concluded that the data support the hypothesis that play fighting can be used by adult rats for social testing, which in this case seems to involve ascertaining the opponent's fighting capability. Aggr. Behav. 25:141–152, 1999. © 1999 Wiley‐Liss, Inc.     

Beyond inference by eye: Statistical and graphing practices in JEAB, 1992‐2017

Debates about the utility of p values and correct ways to analyze data have inspired new guidelines on statistical inference by the American Psychological Association (APA) and changes in the way results are reported in other scientific journals, but their impact on the Journal of the Experimental Analysis of Behavior (JEAB) has not previously been evaluated. A content analysis of empirical articles published in JEAB between 1992 and 2017 investigated whether statistical and graphing practices changed during that time period. The likelihood that a JEAB article reported a null hypothesis significance test, included a confidence interval, or depicted at least one figure with error bars has increased over time. Features of graphs in JEAB, including the proportion depicting single‐subject data, have not changed systematically during the same period. Statistics and graphing trends in JEAB largely paralleled those in mainstream psychology journals, but there was no evidence that changes to APA style had any direct impact on JEAB. In the future, the onus will continue to be on authors, reviewers and editors to ensure that statistical and graphing practices in JEAB continue to evolve without interfering with characteristics that set the journal apart from other scientific journals.     

Stereotype threat may not impact women's inhibitory control or mathematical performance: Providing support for the null hypothesis

Underpinned by the findings of Jamieson and Harkins (2007; Experiment 3), the current study pits the mere effort motivational account of stereotype threat against a working memory interference account. In Experiment 1, females were primed with a negative self- or group stereotype pertaining to their visuospatial ability and completed an anti-saccade eye-tracking task. In Experiment 2 they were primed with a negative or positive group stereotype and completed an anti-saccade and mental arithmetic task. Findings indicate that stereotype threat did not significantly impair women's inhibitory control (Experiments 1 and 2) or mathematical performance (Experiment 2), with Bayesian analyses providing support for the null hypothesis. These findings are discussed in relation to potential moderating factors of stereotype threat, such as task difficulty and stereotype endorsement, as well as the possibility that effect sizes reported in the stereotype threat literature are inflated due to publication bias.     

Cosmopolitics of a Regulatory Fit: The Case of Nanocellulose

Nanocellulose is an organic material envisioned to have the capacity to replace potentially harmful, non-renewable materials such as plastics. Before the material can be utilized commercially within the EU, its safety needs to be officially proven. This is envisioned to happen through the REACH chemicals regulation that controls the market entry of new substances. The regulation proposes concepts to support regulatory discretion and test methods to be used in risk assessments. While so doing, REACH puts forward assumptions pertaining to the critical qualities of innovations. However, when regulation is used to appraise radically new innovations, the assumptions need to be re-evaluated. Yet, analysis of expert accounts suggests that nanocellulose cannot be easily fit into the categorizations and analytical engagements that REACH proposes. For the purposes of a regulatory adoption, the problems are transformed into epistemological issues to be resolved through the incremental closing of knowledge gaps. Some of the key qualities of the material seem not to gain recognition in the regulatory realm that is in the making. At worst, the official strategy may create conditions for risks which the regulation is supposed to eradicate while, at the same time, hindering the development of plastic-substituting solutions.     

Evaluating the Impact of Careless Responding on Aggregated-Scores: To Filter Unmotivated Examinees or Not?

When examinees' test-taking motivation is questionable, practitioners must determine whether careless responding is of practical concern and if so, decide on the best approach to filter such responses. As there has been insufficient research on these topics, the objectives of this study were to: a) evaluate the degree of underestimation in the true mean when careless responses are present, and b) compare the effectiveness of two filtering procedures in purifying biased aggregated-scores. Results demonstrated that: a) the true mean was underestimated by around 0.20 SDs if the total amount of careless responses exceeded 6.25%, 12.5%, and 12.5% for easy, moderately difficult, and difficult tests, respectively, and b) listwise deleting data from unmotivated examinees artificially inflated the true mean by as much as .42 SDs when ability was related to careless responding. Findings from this study have implications for when and how practitioners should handle careless responses for group-based low-stakes assessments.     

心理与教育测验中反应时模型应用的优势与举例

基于计算机形式的测验使得收集作答反应时信息成为可能,这些信息的有效利用对心理与教育测验的理论研究和实际应用产生了重大影响。首先,归纳并总结了测验中使用反应时信息的五大优势。其次,分别介绍了4种不同取向下较典型的反应时模型与模型特征,并分别进行评价。再次,较系统地梳理了反应时模型在实践中的应用,使读者了解反应时信息在测验中所发挥的作用。最后,探讨了未来将反应时应用于心理与教育测量领域的几个研究方向。     

Developing new online calibration methods for multidimensional computerized adaptive testing

Multidimensional computerized adaptive testing (MCAT) has received increasing attention over the past few years in educational measurement. Like all other formats of CAT, item replenishment is an essential part of MCAT for its item bank maintenance and management, which governs retiring overexposed or obsolete items over time and replacing them with new ones. Moreover, calibration precision of the new items will directly affect the estimation accuracy of examinees’ ability vectors. In unidimensional CAT (UCAT) and cognitive diagnostic CAT, online calibration techniques have been developed to effectively calibrate new items. However, there has been very little discussion of online calibration in MCAT in the literature. Thus, this paper proposes new online calibration methods for MCAT based upon some popular methods used in UCAT. Three representative methods, Method A, the ‘one EM cycle’ method and the ‘multiple EM cycles’ method, are generalized to MCAT. Three simulation studies were conducted to compare the three new methods by manipulating three factors (test length, item bank design, and level of correlation between coordinate dimensions). The results showed that all the new methods were able to recover the item parameters accurately, and the adaptive online calibration designs showed some improvements compared to the random design under most conditions.