N-of-1 methods: A practical guide to exploring trajectories of behaviour change and designing precision behaviour change interventions

Objectives(1) To introduce N-of-1 methods and how they can help the researchers identify predictors of behavioural outcomes, (2) to provide examples of studies that test individual theory-based predictions of physical activity and/or exercise; (3) to provide a practical example dataset to illustrate how to design and undertake a basic analysis for an N-of-1 study; and (4) to suggest a future agenda for N-of-1 physical activity and exercise research.DesignFactors for consideration when designing an N-of-1 study include variability of predictors and outcomes, assessment frequency and appropriate analysis methods. Existing literature and piloting can help inform these aspects.MethodsWe use a dataset of 24 individuals who collected data over 28 days to illustrate example analysis procedures. Data, guidance and associated SPSS and R syntax are made available to provide researchers with tools to learn about and practice N-of-1 analysis.ResultsGuidance on dealing with missing data, looking at graphical representations of N-of-1 data, managing autocorrelation using the prewhitening method and analysing N-of-1 datasets is provided. Using the example dataset, we demonstrate how to identify antecedents of physical activity (steps) to assess directionality of associations. We also include an overview of aggregating N-of-1 datasets using multilevel modelling.ConclusionsN-of-1 methodology provides a means of tracking individual patterns of behaviour and identifying potential antecedents of physical activity and exercise to help determine causality. Assisted by mobile technologies, there is great potential to enrich our understanding of movement behaviour using this approach to inform interventions.     

ISOLATING THE INDIVIDUAL: THEOLOGY,THE EVOLUTION OF RELIGION,AND THE PROBLEM OF ABSTRACT INDIVIDUALISM

Debates about the theological implications of recent research in the cognitive and evolutionary study of religion have tended to focus on the question of theism. The question of whether there is any disagreement about the conceptualization of the individual human being has been largely overlooked. In this article, I argue that evolutionary and cognitive accounts of religion typically depend upon a view of cognition that conceptually isolates the mind from its particular social and physical environmental contexts. By embracing this view of the mind, these accounts also unwittingly embrace an abstract individualist view of individual personhood that Christian theologians have explicitly battled against. Taken as a whole, the field leaves sufficient room for supplementary theories that are compatible with theological accounts of the relational individual, but in practice, no effort has been made to engage, or even to accommodate, any other view of individual personhood.     

Opinion on directive 98/44/EC on the legal protection of biotechnical inventions,and its implementation in Sweden

The following statement is the formal opinion by the Swedish National Council on Medical Ethics concerning the implementation of Directive 98/44/EC of the European Parliament concerning legal protection of biotechnical inventions, and the implications and implementation of this Directive in Sweden.     

Bailing and jailing the fast and frugal way

Legal decisions such as the decision to bail upon adjourning a case have major consequences for both defendants and society. In the English system, magistrates, most of whom are lay people, are afforded considerable discretion and must work under constraints such as time pressure. Judgment analysis of the bail decision making policies of 81 magistrates from 44 courts throughout England and Wales revealed intra‐ and inter‐magistrate inconsistency in bail decisions, discrepancies between stated and elicited cue use, and high levels of post‐decisional confidence. Furthermore, magistrates' policies were better described and predicted by a fast and frugal model characterized by noncompensatory cue use, than by either of two compensatory integration models. The fast and frugal model portrays a picture of bail decision making that conflicts with the ideal practice as defined by the due process model of justice. We discuss the implications of these findings for judgment and decision making research and criminal justice policy. Copyright © 2001 John Wiley & Sons, Ltd.     

论医患关系的法律属性

医事法（又称卫生法）究竟是属于民法的调整范畴还是属于行政法的范畴,国内学术界争议很大。从医学科学与医疗行为的本质特征看,医患关系并不具备民事法律关系所必须具备的主体平等、双方自愿及等价有偿互惠互利三大特征中的任何一个特征。同时也不存在行政主体与行政相对人的关系。为此,首次提出医事法既不调整横向的民事法律关系,也不调整纵向的行政法律关系,而是调整斜向的医事法律关系的一门独立的法律体系的理论。     

A Pearson-Type-VII item response model for assessing person fluctuation

Using Lumsden’s Thurstonian fluctuation model as a starting point, this paper attempts to develop a unidimensional item response theory model intended for binary personality items. Under some additional assumptions, a new model is obtained in which the item characteristic curves are defined by a cumulative Pearson-Type-VII distribution, and the person response curves are two-parameter normal ogives. Procedures for fitting the new model are proposed. Furthermore, the relations between individual fluctuation and scalability are discussed, and a scalability index based on the new model is proposed. All the developments in this paper are illustrated using two empirical examples.     

Co‐occurrence of depression and delinquency in personality types

Although the co‐occurrence between adolescent depression and delinquency has been well‐studied, the nature of the longitudinal associations is not yet clear. To clarify this we examined whether personality type is a moderator in the longitudinal co‐occurrence of depression and delinquency. A total of 338 young and middle adolescents completed questionnaires about depression, delinquency and personality in 3 yearly waves of the CONflict And Management Of RElationships (CONAMORE). We found that the stable overcontrollers showed the highest mean level on depression and that the stable undercontrollers showed the highest mean level on delinquency. Furthermore, we demonstrated that the longitudinal co‐occurrence between depression and delinquency was best described by means of a stability model, in which personality type membership proved to be an important moderator. The three personality types differed significantly on the rank‐order stability of both depression and delinquency. Copyright © 2006 John Wiley & Sons, Ltd.     

坚持科学发展观 促进中医药学现代化

中西医各有短长都不要无限夸大自身的优势。中西医互补整合是现代医学发展的潮流。学术争论不要政治化,科技管理要法制化,学者必须从浮华世态中醒悟过来,重建学者应有的人格和道德,纯洁科学的神圣殿堂。坚持科学发展观,中医药学才有长足的进步。     

Perceived organizational structure for teacher liking: the role of peers’ perceptions of teacher liking in teacher–student relationship quality,motivation, and achievement

Previous research has identified the role of perceived peer hierarchies, or organizational structures, in affecting students’ adjustment to school (Lease et al. 2003, Journal of Early Adolescence, 23, 194–217). The purpose of this study was to examine whether middle school classrooms can be described in terms of the perceived status individual students hold for who will and will not be ‘liked’ by the teacher. Specifically we examined: (1) Do students share a mutually agreed on representation, a perceived organizational structure, for describing relative status with their teacher? (2) Are teachers perceived as systematically favoring girls or boys? (3) Are peers’ perceptions of teacher liking associated with individual students’ social and academic motivation and relationship quality with teachers? (4) Are students identified by peers as ‘not liked’ at risk for long-term teacher rejection and underachievement? And, (5) What are the underlying criteria students use to judge teacher likeability? Data for this study were drawn from peer ratings from 516 (262 boys, 254 girls) middle school students in 20 classrooms. Findings indicate multidimensional scaling techniques can be used to map the ‘teacher-liking space,’ accounting for  > 90% of the variability in peers’ ratings of teacher likeability. Additionally, findings indicate perceived status in the teacher-liking space has consequences for students’ achievement and teacher relationship quality.