排序方式: 共有115条查询结果,搜索用时 15 毫秒
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Stevenson CW 《Neurobiology of learning and memory》2011,96(2):315-323
The basolateral amygdala (BLA) and medial prefrontal cortex (mPFC) are inter-connected regions involved in fear memory expression. The reciprocal nature of projections between these areas differs along the rostrocaudal extent of BLA. This study investigated the role of functional interactions between BLA and the prelimbic (PL) subregion of mPFC in mediating contextual fear memory. Freezing served as the measure of conditioned fear. Experiments 1–3 examined the effects of left, right or bilateral infusion of bupivacaine into anterior BLA (aBLA), posterior BLA (pBLA) or PL on fear memory expression. Reversible inactivation of left, right or bilateral aBLA impaired fear memory expression. Bilateral inactivation of pBLA or PL also disrupted the expression of fear memory, although left or right inactivation alone had no significant effects in either region. Experiment 4 examined the effects of functionally disconnecting pBLA and PL on contextual fear memory by infusing bupivacaine unilaterally into pBLA and PL in the ipsilateral or contralateral hemisphere. Fear memory expression was impaired by asymmetric inactivation of pBLA and PL; however, a similar effect was also observed with symmetric inactivation of these regions. Bupivacaine infusion did not affect behavior in the open field, likely ruling out non-specific effects of inactivation on innate fear and locomotor activity. These results demonstrate different roles for rostral and caudal BLA in mediating the expression of contextual fear memory. They also raise the possibility that pBLA–PL circuitry is involved in subserving fear memory expression via complex processing mechanisms, although further research is needed to confirm this preliminary finding. 相似文献
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We present evidence that the supposed processing advantage for an SVfinO word order over an SOVfin word order in German argued for by Weyerts, Penke, Münte, Heinze, and Clahsen (2002) is supported by neither experimental nor theoretical evidence. Specifically, we show (a) that the frontocentral negativity for an SOVfin in comparison to an SVfinO word order in Weyerts et al.'s Experiments 2 and 3 is reducible to more general differences in the electrophysiological responses elicited by nouns versus verbs in a sentence context, and (b) that the P600 difference between the two word orders in Experiment 2, as well as the reading time differences in Experiment 1, result from the fact that the two supposedly ungrammatical conditions actually differ in their degree of ill-formedness. We conclude that there is no evidence for a processing disadvantage for SOVfin, thus reconciling Weyerts et al.'s results on German sentence processing with the grammatical regularities of German. 相似文献
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猜谜作业中顿悟的ERP效应 总被引:3,自引:0,他引:3
采用事件相关电位(ERP)探索问题解决过程中顿悟的神经机制。以猜谜作业为实验程序,对“有顿悟”和“无顿悟”答案引发的脑电分别进行叠加和平均,并将二者相减(有顿悟-无顿悟)得到差异波。在250~500 ms “有顿悟”比“无顿悟”的ERP波形有一个更加负性的偏移,在差异波中,这个负成分的潜伏期约为380 ms(N380)。地形图和电流密度图显示,N380在额中央区活动最强。偶极子源定位分析结果显示,N380可能起源于扣带前回。因此,N380可能反映顿悟问题解决过程中思维定势的突破。 相似文献
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大脑前扣带回皮层与执行功能 总被引:11,自引:2,他引:9
回顾了近期有关大脑前扣带回皮层(ACC)参与执行功能的研究资料。结果显示,ACC可以对正在进行的目标定向行为实施在线监控,在出现反应冲突或错误时提供信号,以便能及时调整与分配注意资源,因此可能是一个行为规划与执行的高级调控结构。这两年来的新发现提示,ACC的执行监控作用可能是基于动机与奖赏期待做出的对“意志行动”的整合性控制,并可能具有对行动结果的情绪评价意义。 相似文献
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为了探索不同方位辨别方式的男女差异,采用自编的经过心理测量学检测符合指标的空间知觉量表和三个语言线索下方位辨别任务范式实验,在测验和实验3中设计两种空间知觉加工方式,即东西南北和前后左右;在实验1中设计东西南北;在实验2中设计前后左右。测验,实验1和实验3均发现,在东西南北方位辨别上存在显著的性别差异,且男生优于女生;测验,实验2和实验3均发现,在前后左右方位辨别上不存在显著的性别差异。这表明男生更擅长于使用东西南北的方位辨别方式。 相似文献
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Functional mapping of left parietal areas involved in simple addition and multiplication. A single‐case study of qualitative analysis of errors 下载免费PDF全文
Alessandro Della Puppa Serena De Pellegrin Elena Salillas Alberto Grego Anna Lazzarini Antonino Vallesi Marina Saladini Carlo Semenza 《Journal of Neuropsychology》2015,9(2):330-335
All electrostimulation studies on arithmetic have so far solely reported general errors. Nonetheless, a classification of the errors during stimulation can inform us about underlying arithmetic processes. The present electrostimulation study was performed in a case of left parietal glioma. The patient's erroneous responses suggested that calculation was mainly applied for addition and a combination of retrieval and calculation was mainly applied for multiplication. The findings of the present single‐case study encourage follow up with further data collection with the same paradigm. 相似文献
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Theoretically, stimuli can be related to the self as subject (“I”) or object (“ME”) of experience. This event-related brain potential (ERP) study investigated whether listening to personal and possessive pronouns elicits different modes of self-processing regarding time-course and neural sources. Going beyond previous research, first (1PP) and second person (2PP) pronouns were included to determine the specificity of self-processing. Participants listened passively to German pronouns while the electroencephalogram was recorded. Modulation of ERPs revealed a processing advantage for the 2PP personal pronoun “du” (“you”) already in early time windows. Regarding possessive pronouns, N1 amplitudes indicated increased attention orientation to the 1PP pronoun “mein” (“my”), whereas during later time windows, processing of 1PP and 2PP possessive pronouns did not differ but differed from the third person pronoun “sein” (“his”). ERP source imaging suggests that primary sensory brain regions (auditory cortex), the insula and cortical midline structures are differentially involved into these two processing modes. The results support the idea of distinct self-processing modes (“I” and “ME”) and confirm their dynamic nature. Moreover, they demonstrate that on a neural level neither “I” or “ME” are invariantly tied to the first person, in line with the hypothesis that self-processing is relational and context-dependent. 相似文献
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Lucian Gideon Conway III Shannon C. Houck Laura Janelle Gornick Meredith A. Repke 《Political psychology》2018,39(5):1049-1067
Although past research suggests authoritarianism may be a uniquely right‐wing phenomenon, the present two studies tested the hypothesis that authoritarianism exists in both right‐wing and left‐wing contexts in essentially equal degrees. Across two studies, university (n = 475) and Mechanical Turk (n = 298) participants completed either the RWA (right‐wing authoritarianism) scale or a newly developed (and parallel) LWA (left‐wing authoritarianism) scale. Participants further completed measurements of ideology and three domain‐specific scales: prejudice, dogmatism, and attitude strength. Findings from both studies lend support to an authoritarianism symmetry hypothesis: Significant positive correlations emerged between LWA and measurements of liberalism, prejudice, dogmatism, and attitude strength. These results largely paralleled those correlating RWA with identical conservative‐focused measurements, and an overall effect‐size measurement showed LWA was similarly related to those constructs (compared to RWA) in both Study 1 and Study 2. Taken together, these studies provide evidence that LWA may be a viable construct in ordinary U.S. samples. 相似文献