Task-load manipulation in the Symbol Digit Modalities Test: An alternative measure of information processing speed

ObjectiveTo evaluate the utility of an oral fMRI-adapted version of the Symbol Digit Modalities Test (SDMT) to assess information processing speed (IPS) using three different interstimulus intervals (ISI).MethodsNineteen right-handed healthy controls performed the adapted version of the SDMT, consisting of a block design that had a total of 6 control/activation block pairs with 3 different ISIs (1.5, 2 and 2.5 s) presented in two different runs: in ascending and descending orders. The brain activation patterns during different ISIs were assessed by effective functional connectivity analysis based on independent component analysis.ResultsAs expected, all conditions yielded activations in the fronto-parietal networks (FPNs) related to attention processes. Shorter ISIs (1.5 and 2 s) not only yielded greater patterns of connectivity within fronto-parietal and occipital regions such as the FPN and fronto-occipital network (FON), but also recruited more functional networks overall. Task performance at the shortest ISI was negatively correlated with connectivity at the FPN and activity of the pre-supplementary motor area extending to the cingulate gyrus.ConclusionIncreasing IPS demands due to shorter ISIs resulted in an increased level and number of functional networks required, increased connectivity within the FPN and FON, and enhancement of the prefrontal cortex. IPS does not arise from activity of a single b area but from affective information transfer among distant cortical regions of the frontal and parietal cortices. This adapted version of the SDMT may be useful for studying alterations of IPS in clinical and nonclinical populations.     

The amygdalostriatal and corticostriatal effective connectivity in anticipation and evaluation of facial attractiveness

Decision-making consists of several stages of information processing, including an anticipation stage and an outcome evaluation stage. Previous studies showed that the ventral striatum (VS) is pivotal to both stages, bridging motivation and action, and it works in concert with the ventral medial prefrontal cortex (vmPFC) and the amygdala. However, evidence concerning how the VS works together with the vmPFC and the amygdala came mainly from neuropathology and animal studies; little is known about the dynamics of this network in the functioning human brain. Here we used fMRI combined with dynamic causal modeling (DCM) to investigate the information flow along amygdalostriatal and corticostriatal pathways in a facial attractiveness guessing task. Specifically, we asked participants to guess whether a blurred photo of female face was attractive and to wait for a few seconds (“anticipation stage”) until an unblurred photo of feedback face, which was either attractive or unattractive, was presented (“outcome evaluation stage”). At the anticipation stage, the bilateral amygdala and VS showed higher activation for the “attractive” than for the “unattractive” guess. At the outcome evaluation stage, the vmPFC and the bilateral VS were more activated by feedback faces whose attractiveness was congruent with the initial guess than by incongruent faces; however, this effect was only significant for attractive faces, not for unattractive ones. DCM showed that at the anticipation stage, the choice-related information entered the amygdalostriatal pathway through the amygdala and was projected to the VS. At the evaluation stage, the outcome-related information entered the corticostriatal pathway through the vmPFC. Bidirectional connectivities existed between the vmPFC and VS, with the VS-to-vmPFC connectivity weakened by unattractive faces. These findings advanced our understanding of the reward circuitry by demonstrating the pattern of information flow along the amygdalostriatal and corticostriatal pathways at different stages of decision-making.     

Magnitude and determinants of behavioral risk reduction: Longitudinal analysis of a cohort at risk for AIDS

The magnitude and predictors of longitudinal behavioral change are reported in a cohort of homosexual men at risk for AIDS. Self-reports of sexual behavior were obtained at two points in time separated by an interval of approximately six months. These self-reports were used to construct both dichotomous and continuous measures of changes in behavior consistent with reduction in the transmission of the AIDS virus (HIV). Although there was considerable variability in behavior. mean changes were consistently in the desired direction. Avoidance of anonymous sexual partners, monogamy, and modification of receptive anal sex to reduce exposure to semen by condom use or withdrawal prior to ejaculation appeared to be especially important in this cohort. Both multiple linear regression and multiple logistic regression were used to examine the relationship between a model of health behavior and these outcomes. Variables examined included knowledge of AIDS. perceived risk of AIDS. the perceived efficacy of behavior in reducing AIDS risk, difficulties with sexual impulse control, belief in biomedical technology to provide a prevention or cure, social norms supportive of behavioral change, and gay network affiliation. Of all these factors, only the availability of supportive peer norms was consistently, significantly and positively related to multiple measures of outcome. Differences between these analyses and longitudinal analyses reported elsewhere are discussed. These results suggest the policies regarding HIV antibody testing should be developed cautiously. taking account of the failure of a sense of risk to predict subsequent behavioral change. They also emphasize the important role of gay organizations in developing social norms supportive of behavioral risk reduction.     

The impact of interpersonal affective relationships and awareness on expertise seeking: A multilevel network investigation

Transactive memory theory suggests that general awareness of expertise location in a group is sufficient to predict expertise seeking. Yet expertise seeking is, at least in part, a social phenomenon between two individuals embedded in a network of social relationships. Taking a multilevel, network perspective, we examined the interplay of affective relationships and awareness on expertise seeking in groups. Hypotheses were tested using network data collected from 693 employees in 53 sales groups. HLM analysis results indicated that awareness of expertise distribution positively influenced the decision to seek expertise at all levels of analysis examined. In addition, both positive and negative affective relationships influenced expertise seeking, although their pattern of influence differed across different levels of analysis. More specifically, having either a positive or a negative affective relationship with another group member affected the decision to seek expertise from that person. Although having many positive relationships had a positive effect on expertise seeking, having many negative affective relationships had no effect. Moreover, having both an awareness and a positive affective relationship with another group member amplified their positive effect on expertise seeking. Last, individuals who had more negative affective ties were less likely to leverage the positive impact of each awareness relationship on expertise seeking.     

Influencing value priorities and increasing well-being: The effects of reflecting on intrinsic values

A four-week experimental study (N?=?113) examined the effects of reflecting on intrinsic values. In the experimental group, participants learned about the distinction between intrinsic (e.g. having close relationships) and extrinsic (e.g. being popular) values, wrote about two personal intrinsic values, and then reflected on these values weekly for four weeks. In the control group, participants completed parallel exercises related to the daily details of their lives. Results revealed that participants in the intrinsic values group experienced greater well-being immediately following the written reflection than participants in the control group. Four weeks later, the more engaged participants felt in the reflection exercises, the more they prioritized intrinsic over extrinsic values and the greater their well-being. These effects occurred only for participants in the intrinsic values condition. The implications for changing value priorities and improving well-being are discussed.     

Imageability,age of acquisition,and frequency factors in acronym comprehension

In spite of their unusual orthographic and phonological form, acronyms (e.g., BBC, HIV, NATO) can become familiar to the reader, and their meaning can be accessed well enough that they are understood. The factors in semantic access for acronym stimuli were assessed using a word association task. Two analyses examined the time taken to generate a word association response to acronym cues. Responses were recorded more quickly to cues that elicited a large proportion of semantic responses, and those that were high in associative strength. Participants were shown to be faster to respond to cues which were imageable or early acquired. Frequency was not a significant predictor of word association responses. Implications for theories of lexical organisation are discussed.     

The Intrinsic Value of Sport: A Reply to Culbertson

Leon Culbertson's recent contribution, ‘Does Sport Have Intrinsic Value?’ objects to the account of the value of sport as intrinsic value I had developed in my Sport, Rules and Values; in particular, as this occurs in my argument that the value of some sports resided in the possibility of their functioning as a moral laboratory. He identifies two accounts of intrinsic value; and shows that neither would fit my purposes seamlessly. He urges that my account of the place of normative reasons cannot generate intrinsic value: rather, the person whose reasons they are somehow imports that value. Yet he has misunderstood my particularist conception of values; and the place occupied by my contextualism – these, rather than a residual commitment to essentialism, are what generates an apparent inconsistency he identifies. But they also explain it away. As a result, much of his concern to find some exact account of the term ‘intrinsic’ is misplaced: we need to look contextually. Further, the project of my discussion was limited to showing, first, how the moral laboratory idea might explain the value of some sport (on the assumption that sport had intrinsic value); and, second, how failures of realisation of that intrinsic value might be traced to the distinction between motivating reasons and normative ones.     

God and Evolutionary Evil: Theodicy in the Light of Darwinism

Pain, suffering, death, and extinction have been intrinsic to the process of evolution by natural selection. This leads to a real problem of evolutionary theodicy, little addressed up to now in Christian theologies of creation. The problem has ontological, teleological, and soteriological aspects. The recent literature contains efforts to dismiss, disregard, or reframe the problem. The radical proposal that God has no long–term goals for creation, but merely keeps company with its unfolding, is one way forward. An alternative strategy to tackle the problem of evolutionary theodicy is outlined, with an implication for environmental ethics and suggestions for further work.     

内外部线索对学习判断的影响

该研究针对Koriat和Dunlosky实验研究结果的不同,通过两个实验,进一步考察内外部线索对学习判断（judgment of learning,简称为JOL）的影响。被试为山东师大本科生63名。内部线索词对的语义联系,两种外部线索分别是呈现时间和呈现顺序。本研究结果表明：（1）无论在交替呈现还是区组呈现条件下,内部线索对JOL和回忆都产生了显著影响;（2）呈现顺序和呈现时间可能是两种不同类型的外部线索;（3）不同的内外部线索对JOL有不同的交互作用;（4）实验二中无意义词对先呈现组的JOL大于有意义词对先呈现组的JOL,这说明JOL可能存在“锚定效应”。