Insights into spared memory capacity in amnestic MCI and Alzheimer's Disease via minimal interference

Impairment on standard tests of delayed recall is often already maximal in the aMCI stage of Alzheimer's Disease. Neuropathological work shows that the neural substrates of memory function continue to deteriorate throughout the progression of the disease, hinting that further changes in memory performance could be tracked by a more sensitive test of delayed recall. Recent work shows that retention in aMCI patients can be raised well above floor when the delay period is devoid of further material - 'Minimal Interference'. This memory enhancement is thought to be the result of improved memory consolidation. Here we used the minimal interference/interference paradigm (word list retention following 10 min of quiet resting vs. picture naming) in a group of 17 AD patients, 25 aMCI patients and 25 controls. We found (1) that retention can be improved significantly by minimal interference in patients with aMCI and patients with mild to moderate AD; (2) that the minimal interference paradigm is sensitive to decline in memory function with disease severity, even when performance on standard tests has reached floor; and (3) that this paradigm can differentiate well (80% sensitivity and 100% specificity) between aMCI patients who progress and do not progress to AD within 2 years. Our findings support the notion that the early memory dysfunction in AD is associated with an increased susceptibility to memory interference and are suggestive of a gradual decline in consolidation capacity with disease progression.     

Reducing the barriers to accessing psychological therapies for Bengali,Urdu, Tamil and Somali communities in the UK: some implications for training,policy and practice

The aim of this research was to investigate the feasibility of achieving Improving Access to Psychological Therapies (IAPT) for people from Black, Asian and Minority Ethnic (BAME) communities living in the UK, with specific reference to Bengali, Urdu, Tamil and Somali speaking communities. Focus groups were carried out with each of the communities to investigate how they conceptualise and experience ‘mental health issues’ and what they do when faced with what they regard as these issues. A thematic analysis of the data suggested that participants did not fully understand common conceptualisations about mental health issues, nor did they know how to seek mental health support. Implications of cultural barriers and recommendations for IAPT outcomes for the four communities are discussed.     

汉字字谜任务中限制解除的电生理机制

尽管“限制解除”作为一种顿悟问题解决的关键途径早在上世纪90年代就被德国心理学者Knoblich及其同事提出, 但学界对于“限制解除”所包含的信息加工程序、阶段以及相应的脑认知过程却并未有进一步的探讨和细化。本文从“限制解除”的理论角度出发, 以答案提示催化的“诱发式”字谜解决顿悟为例, 首次提出了一个关于“诱发式”限制解除过程的信息加工阶段初步构想。该构想认为：顿悟问题解决中的“诱发式”限制解除过程包含3个不同的信息加工阶段。第一阶段是以早期注意参与为特征的冲突信息的预警或预处理过程; 第二阶段是以新旧思路交替为特征的关键限制解除过程, 鉴于这个过程以基本问题表征空间的拓展为特征, 因此我们推测右脑的活动很有可能在这个过程中占据主导地位; 第三阶段是以自上而下的控制加工为特征的重新整合过程。脑电研究数据部分地支持了本研究的假设, 发现了上述第一阶段在脑电变化上体现为顿悟性限制解除所伴随的N100/P200复合体; 第二阶段体现为P300在300~400 ms的时间窗内的地形图分布及差异波; 而第三阶段则体现为N400在400~800 ms内的变化。脑电结果还证实：在第二阶段也就是限制解除的关键阶段, 右脑的活动明显强于左脑, 提示基本问题空间的拓展可能更多地依赖于右脑, 而在第三阶段也就是信息的重新整合阶段则表现出相反的半球偏侧化倾向。上述发现有可能为进一步认识和理解顿悟中“限制解除”的脑认知机理提供了新的见解。     

Happy to See Me,Aren’t You,Sally? Signal Detection Analysis of Emotion Detection in Briefly Presented Male and Female Faces

Using signal detection methods, possible effects of emotion type (happy, angry), gender of the stimulus face, and gender of the participant on the detection and response bias of emotion in briefly presented faces were investigated. Fifty-seven participants (28 men, 29 women) viewed 90 briefly presented faces (30 happy, 30 angry, and 30 neutral, each with 15 male and 15 female faces) answering yes if the face was perceived as emotional and no if it was not perceived as emotional. Sensitivity [d', z(hit rate) minus z(false alarm rate)] and response bias (β, likelihood ratio of "signal plus noise" vs. "noise") were measured for each face combination for each presentation time (6.25, 12.50, 18.75, 25.00, 31.25 ms). The d' values were higher for happy than for angry faces and higher for angry-male than for angry-female faces, and there were no effects of gender-of-participant. Results also suggest a greater tendency for participants to judge happy-female faces as emotional, as shown by lower β values for these faces as compared to the other emotion-gender combinations. This happy-female response bias suggests, at least, a partial explanation to happy-superiority effects in studies where performance is only measured as percent correct responses, and, in general, that women are expected to be happy.     

Message sidedness in advertising: the moderating roles of need for cognition and time pressure in persuasion

Persuasion has been extensively researched for decades. Much of this research has focused on different message tactics and their effects on persuasion (e.g., Chang & Chou, 2008; Lafferty, 1999). This research aims to assess whether the persuasion of a specific type of message is influenced by need for cognition (NFC) and time pressure. The 336 undergraduates participated in a 2 (message sidedness: one-sided/two-sided) × 3 (time pressure: low/moderate/high) between-subjects design. Results indicate that two-sided messages tend to elicit more favorable ad attitudes than one-sided messages. As compared with low-NFC individuals, high-NFC individuals are likely to express more favorable ad attitudes, brand attitudes and purchase intention. Moderate time pressure tends to lead to more favorable ad attitudes than low time pressure and high time pressure. In addition, moderate time pressure is likely to elicit more favorable brand attitudes and purchase intentions than high time pressure, but does not elicit more favorable brand attitudes and purchase intentions than low time pressure. Furthermore, when high-NFC individuals are under low or moderate time pressure, two-sided messages are more persuasive than one-sided messages; however, message sidedness does not differentially affect the persuasion when high-NFC individuals are pressed for time. In contrast, one-sided messages are more persuasive than two-sided messages when low-NFC individuals are under low or high time pressure, and two-sided messages are more persuasive than one-sided messages when low-NFC individuals are under moderate time pressure.     

Modulation of N400 in chronic non-fluent aphasia using low frequency Repetitive Transcranial Magnetic Stimulation (rTMS)

Low frequency Repetitive Transcranial Magnetic Stimulation (rTMS) has previously been applied to language homologues in non-fluent populations of persons with aphasia yielding significant improvements in behavioral language function up to 43 months post stimulation. The present study aimed to investigate the electrophysiological correlates associated with the application of rTMS through measurement of the semantic based N400 Event-related brain potentials (ERP) component. Low frequency (1 Hz) rTMS was applied to the anterior portion of the homologue to Broca’s area (pars triangularis), for 20 min per day for 10 days, using a stereotactic neuronavigational system. Twelve non-fluent persons with aphasia, 2-6 years post stroke were stimulated. Six participants were randomly assigned to receive real stimulation and six participants were randomly assigned to receive a blind sham control condition. ERP measures were recorded at baseline, 1 week and 2 months subsequent to stimulation. The findings demonstrate treatment related changes observed in the stimulation group when compared to the placebo control group at 2 months post stimulation indicating neuromodulation of N400 as a result of rTMS. No treatment related changes were identified in the stimulation group, when compared to the sham group from baseline to 1 week post stimulation. The electrophysiological results represent the capacity of rTMS to modulate neural language networks and measures of lexical-semantic function in participants with non-fluent aphasia and suggest that time may be an important factor in brain reorganization subsequent to rTMS.     

No evidence for a General Factor of Personality in the HEXACO Personality Inventory

There have been an increasing number of articles that have speculated on the existence of a General Factor of Personality (GFP) similar to ‘g’ in intelligence research. In this study, I provide evidence that this general factor may be an artifact of the personality instrument used. Specifically, in two samples I show that depending on the type of analysis used there is either no evidence for a GFP in the HEXACO Personality Inventory or the GFP is found to be uncorrelated to GFPs based on Big Five or FFM instruments.     

Do physical and relational aggression explain adolescents' friendship selection? The competing roles of network characteristics,gender, and social status

The role of physical and relational aggression in adolescents' friendship selection was examined in a longitudinal sample of 274 Chilean students from 5th and 6th grade followed over 1 year. Longitudinal social network modeling (SIENA) was used to study selection processes for aggression while influence processes were controlled for. Furthermore, the effects of network characteristics (i.e., reciprocity and transitivity), gender, and social status on friendship selection were examined. The starting assumption of this study was that selection effects based on aggression might have been overestimated in previous research as a result of failing to consider influence processes and alternative characteristics that steer friendship formation. The results show that selection effects of both physical and relational aggression disappeared when network effects, gender, and social status were taken into account. Particularly gender and perceived popularity appeared to be far more important determinants of friendship selection over time than aggression. Moreover, a peer influence effect was only found for relational aggression, and not for physical aggression. These findings suggest that similarity in aggression among befriended adolescents can be considered to be mainly a by-product rather than a leading dimension in friendship selection.     

Commonly-defined and individually-defined posttraumatic growth in the US and Japan

Posttraumatic growth (PTG) is the experience of positive change resulting from the struggle with major life crises. Research on PTG has relied on instruments such as the Posttraumatic Growth Inventory (PTGI: Tedeschi &; Calhoun, 1996), in which items that describe positive changes are assumed to represent personal growth equally for all people. However, some positive changes may indicate greater growth for some people. Individually-defined PTG may differ from commonly-defined PTG. The purpose of this study was to explore the relationships between these two definitions of PTG and how culture affects them. Participants from the US (n = 456) and Japan (n = 279) indicated the degree to which each change in the PTGI represented personal growth. Results from mixed-model analyses of variance revealed that there were main effects for defined growth as well as interaction effects for all PTGI factors. For example, US participants reported greater growth on the factors Relating to Others and New Possibilities for the commonly-defined level, but once individually-defined PTG was considered, growth scores for US participants decreased substantially, and more so than for Japanese participants. Discussion addresses cultural and individual differences in the subjective definitions of PTG and highlights several directions for future research.