AF-DX 116, a Presynaptic Muscarinic Receptor Antagonist, Potentiates the Effects of Glucose and Reverses the Effects of Insulin on Memory

Male Swiss mice were tested 24 h after training in a one-trial step-through inhibitory avoidance task. Low subeffective doses of -(+)-glucose (10 mg/kg, ip), but not its stereoisomer -(−)-glucose (30 mg/kg, ip), administered immediately after training, and AF-DX 116 (0.3 mg/kg, ip), a presynaptic muscarinic receptor antagonist, given 10 min after training, interact to improve retention. Insulin (8 IU/kg, ip) impaired retention when injected immediately after training, and the effects were reversed, in a dose-related manner, by AF-DX 116 (0.3, 1.0, or 3.0 mg/kg, ip) administered 10 min following insulin. Since AF-DX 116 possibly blocks autoreceptors mediating the inhibition of acetylcholine release from cholinergic nerve terminals, the present data support the view that changes in the central nervous system glucose availability, subsequent to modification of circulating glucose levels, influence the activity of central cholinergic mechanisms involved in memory storage of an inhibitory avoidance response in mice.     

The legacy of Guttman and Kalish (1956): Twenty-five years of research on stimulus generalization

This paper is a selective review of the methods, problems, and findings in the area of operant stimulus generalization over the 25 years since the publication of the original paper by Guttman and Kalish (1956) on discriminability and spectral generalization in the pigeon. The paper falls into five main sections, which encompass the main themes and problems stemming from the Guttman and Kalish work and its immediate successors. The first section addresses the relationship between stimulus generalization and stimulus control, as well as the variety of testing procedures and dependent variables used to measure generalization. The next section reviews the limited literature on the effects of early rearing on the generalization gradient. The relationship between discriminability among test stimuli and the slope of the spectral gradient is discussed in the third section, with emphasis upon recent reassessments of the pigeon's hue discriminability function. The fourth section reviews the topic of inhibitory stimulus control, one which developed with the discovery of the peak shift following intradimensional discrimination training. Problems of definition and measurement are discussed in conjunction with the gradient forms used to index inhibitory control. The last section is devoted to attentional effects and the two principal theories postulated to account for them. A survey of different attentional paradigms is provided and the possible role of constant irrelevant stimuli as a source of control is examined. A brief conclusion summarizes the contribution of the generalization technique toward an understanding of the nature and acquisition of stimulus control.     

A Propositional Dynamic Logic with Qualitative Probabilities

This paper presents an -completeness theorem for a new propositional probabilistic logic, namely, the dynamic propositional logic of qualitative probabilities (D Q P), which has been introduced by the author as a dynamic extension of the logic of qualitative probabilities (Q P) introduced by Segerberg.     

The recognition of affective states associated with players’ non-verbal behavior in volleyball

The visible non-verbal behavior of volleyball players after a point might indicate their affective state. The purpose of the present study was to investigate whether the point outcome (i.e., win vs. loss) and the importance of the situation (i.e., first vs. fifth set) influence how well the affective states (indexed through non-verbal behavior) can be recognized. For this purpose, 111 participants were presented 60 video excerpts showing the non-verbal behavior of volleyball teams immediately after a rally and asked whether the shown team had just won or lost a point. The results indicated that the recognition rate was significantly higher for won (80.09%) than for lost points (65.56%) as well as for points of the fifth set (77.84%) than for points of the first set (68.51%). Furthermore, an explorative analysis showed that the recognition rate was significantly higher for won points of the fifth set (89.19%) than for those of the first set (72.13%).     

Associations between power,stress, and dominance in romantic relationships during the COVID-19 pandemic: Examining curvilinear and within-person effects

Two key processes in romantic relationships—power and dominance—can contribute to relationship disruption, but the association between these variables is complex. Elucidating the association between power and dominance during the COVID-19 pandemic is particularly important given the economic, social, and health-related stressors that pose a risk to relationship health. We examined associations between power, stress, and dominance by recruiting 1813 participants to complete an initial online survey at the beginning of the COVID-19 pandemic. Participants were contacted 10 and 22 months later to complete follow-up surveys. Results revealed two main effects: individuals who had greater relationship power and experienced more COVID-19-related stressors than other people engaged in more dominance behaviors. A significant curvilinear effect revealed that at low levels of power, power was not associated with dominance behaviors. However, once power surpassed low levels, individuals with more power engaged in more dominance behaviors. Finally, people engaged in more dominance behaviors when they experienced more power and stress compared to their own average (i.e., within-person effects) during the pandemic. Implications for theories of power, dominance, and relationship disruption and distress are discussed.     

Exploring the peer status prototypes: A large-scale latent profile analysis on high-school students from four European countries

Peer status – the regard other group members have of an individual – is fundamental for youth development. Different research traditions developed independent theoretical frameworks conceiving the dimensions underlying social status, and this led to identifying a variety of peer status prototypes. In this work, we explored whether a classification based on the four dimensions of popularity, aggression, dislike, and victimization could integrate the scattered peer status profiles found in the different traditions. A latent profile analysis on 16,224 European students identified the peer status prototypes of popular, bullies, disliked, victims, and average students. Both the peer- and self-reported correlates supported that the five profiles accounted for the large variety of the students' profiles in the literature. These findings suggest that the adoption of a multidimensional approach supported by advanced statistical procedures could identify students' peer status profiles more effectively, replacing classifications based on cutoffs, and leading to a unified students' classification.     

海洛因依赖者抑制控制功能的损伤机制及其可逆性

抑制控制障碍是海洛因依赖者认知功能受损的核心问题, 是影响复吸的关键因素。大量研究证实了海洛因依赖者抑制控制功能的受损, 并且发现长期药物滥用者额叶、前扣带回皮层、中脑腹侧被盖区、伏隔核、脑岛等相关脑区活动存在异常。以往研究表明海洛因依赖者抑制控制功能受损是一种持久性的、不可逆的脑损伤, 但最近一些研究却提供了毒品戒断者抑制控制功能生物性恢复的证据。未来的研究应该更加关注多重冲突条件下海洛因依赖者抑制控制功能的研究, 并且在戒毒实践中根据海洛因戒断者自身特点进行区分性治疗。     

Losing to Terrorism: An American Work in Progress

Abstract: The evolution of the U.S. war on terrorism is on a path that poses a substantial probability of losing to it, although not necessarily of a victory by its declared targets. That conclusion follows from the definition presented of terrorism and thus central questions about the merits of responses justified by an objective of reducing it. Likely American responses to 9/11 are suggested by a review of well‐known policy‐making tendencies from past scholarship and experience, tendencies well‐established prior to 9/11 and by no means unique to the Bush II presidency. The expectations those tendencies suggest have been born out by what the United States has done and not done. Well‐established criteria and their implied rules of practice for security enhancing great‐power statecraft are presented, and the chosen U.S. program of action is found to be counter‐productive in their light.     

Vocational choice: A decision making perspective

We propose a model of vocational choice that can be used for analyzing and guiding the decision processes underlying career and job choices. Our model is based on research in behavioral decision making (BDM), in particular the choice goals framework developed by Bettman, Luce, and Payne (1998). The basic model involves two major processes. First, the selection of a decision strategy according to four choice goals: maximizing decision accuracy, minimizing cognitive effort, minimizing negative emotion, and maximizing justifiability of the decision. Second, the construction of situation-specific preferences, which can reflect irrelevant task and context factors such as the evaluation mode. This basic model is extended to account for social influences and the long decision time typical of most career and job decisions. We review research on vocational choice in light of this model, discuss normative implications for counseling, and outline a research agenda for studying vocational choice from a behavioral decision making perspective.     

Cognitive and social comparison processes in brainstorming

This brainstorming experiment assessed the extent to which idea exposure produced cognitive stimulation and social comparison effects. One hundred and sixty participants were exposed to either a high or low number of common or unique ideas. The participants’ likelihood of engaging in social comparison processes (high or low) was also manipulated through instructional sets. The results indicated both cognitive stimulation and social comparison effects. Exposure to a high number of ideas and to common ideas enhanced the generation of additional ideas. The effects of exposure to a high number of ideas was greater under high than under low social comparison conditions. Finally, recall of exposed ideas was related to enhanced idea generation. These results are consistent with the social/cognitive influence model of group brainstorming (Paulus, Dugosh, Dzindolet, Putman, & Coskun, 2002).