急性心肌梗死患者院前延误的影响因素

急性心肌梗死(AMI)患者的治疗关键在于早期诊断和及时开通闭塞的冠状动脉,患者在发病后能否及早到院接受再灌注治疗,对患者的治疗效果和预后有重要影响.院前延误时间(PDT)即为从患者出现症状至到达医院接受治疗的时间.AMI患者就医大多是延迟的,主要原因是患者不能决定自己的症状是否需要治疗,也就是患者决定就医时间延长.本研究目的是分析造成急性心肌梗死患者院前延误的相关影响因素,为患者赢得最佳治疗时间提供理论依据.     

幸福的体验效用与非理性决策行为的偏差机制

基于体验效用的幸福包括预期幸福、即时幸福和回忆幸福,这三者有极其重要的本质差异,导致决策偏差和非理性。本研究运用行为科学和认知神经科学相结合的研究方法,首次从行为层次—信息加工层次—脑神经层次三个层面,立体地开展幸福感的体验效用与非理性决策行为研究。研究计划分为三个部分:(1)预期幸福、即时幸福和回忆幸福的本质特点和行为规律;(2)三种体验效用产生偏差的认知心理机制;(3)体验效用与非理性决策偏差的脑神经机制。通过系列研究,拟解决三个关键问题:(1)在人类判断与决策过程中,预期、即时和回忆三种效用是如何影响人们的判断与决策?(2)三种体验效用出现偏差的信息加工特点和脑神经机制究竟是什么?(3)三种效用的偏差规律及对政府公共政策的启示。对这些问题的深入探讨,不仅对决策理论研究的发展是一个贡献;对政府管理制定有效的公共政策,避免"牺牲体验追求指标",解决"幸福悖论",同样有很强的实践指导意义。     

不同年龄广告名人效应的心理加工机制研究

本研究从自动化加工和控制性加工这个视角研究了名人效应的心理加工机制。实验运用加工分离程序,探讨了不同年龄阶段的受众对名人广告的信息加工模式。结果发现：(1)名人效应是一个普遍存在的现象,与用一般消费者做代言人相比,青少年、成年人(大学生)以及老年人对名人广告均明显存在更多的自动化加工,且加工水平没有年龄差异。但是,老年人的控制性加工明显低于其他两组;(2)在非注意条件下,代言人的专业化程度明显地影响了大学生组的控制性加工,但与各组被试的自动化加工都关系不大。这些研究发现为广告策略的制定带来了一些新的启示。     

Self-deception as affective coping. An empirical perspective on philosophical issues

In the philosophical literature, self-deception is mainly approached through the analysis of paradoxes. Yet, it is agreed that self-deception is motivated by protection from distress. In this paper, we argue, with the help of findings from cognitive neuroscience and psychology, that self-deception is a type of affective coping.First, we criticize the main solutions to the paradoxes of self-deception. We then present a new approach to self-deception. Self-deception, we argue, involves three appraisals of the distressing evidence: (a) appraisal of the strength of evidence as uncertain, (b) low coping potential and (c) negative anticipation along the lines of Damasio’s somatic marker hypothesis. At the same time, desire impacts the treatment of flattering evidence via dopamine. Our main proposal is that self-deception involves emotional mechanisms provoking a preference for immediate reward despite possible long-term negative repercussions. In the last part, we use this emotional model to revisit the philosophical paradoxes.     

Eighteenth-century French materialism clockwise and anticlockwise

ABSTRACT

Because of their reliance on mechanistic metaphors and analogies referring to machines, the eighteenth-century materialists La Mettrie and Diderot have sometimes been described as ‘mechanistic materialists’. However, if one pays close attention to the ways in which mechanical analogies and metaphors were used in eighteenth-century French materialism, one sees that the recourse to these metaphors and comparisons in no way implies mechanism in the sense of physicalist reductionism. Instead, early instances of these comparisons appear in arguments pointing out that technological artefacts have functional properties which are not reducible to their physical properties. When La Mettrie compares man to a machine in his L'homme machine, he insists at the same time on the fact that, just like a machine, man is a cultural artefact. According to La Mettrie, man's very existence depends on language and culture, and it is precisely this dependence on culture which distinguishes him from other animals. However, La Mettrie's sceptical stance renders his position towards physicalistic reductionism ambiguous. Diderot, who by contrast was interested in the distinction between the living and non-living, distances himself from the ambiguous use of mechanistic metaphors and insists on the irreducibility of physiological and biological phenomena to the physical.     

Varieties of early modern materialism

ABSTRACT

This paper discusses how early modern materialism can be defined and delineated, before turning to a brief survey of the main philosophical resources early modern materialist theories draw on. Subsequently, I discuss competing overall narratives concerning early modern materialism, and conclude with a defence of the controversial view that material soul theories belong to materialism proper.     

Theology, Science, and Postmodernism: Responding to Stanley Grenz

This article responds to Stanley J. Grenz's Templeton Lecture, “Why Do Theologians Need to Be Scientists?” published in the June 2000 issue of Zygon (Grenz 2000). In the first part I outline my reasons for finding the kind of theological reflections in which Grenz engages worthy of attention by noting my disagreement with the view that a sufficient response to theological issues can be formulated on the basis of an examination of our biological nature. I assert, in that connection, the autonomy of reason as a way of investigating and understanding the world. In the second part I respond directly to Grenz by explaining my disagreement with the postmodern critique of science upon which he relies and his adherence to Christian eschatology as an answer to the conundrums into which, he posits, we are drawn as a result of that critique. I note that I agree with Grenz, however, that the activity of valuing is necessarily a forward‐looking Godlike endeavor that is not derivable from science. In the third part I suggest that we must be open to the investigation of the possible existence of an objective realm of value and that, in any case, rejection of the postmodern critique of science in many cases pro‐vides a sound basis for the disciplined resolution of factual questions that frequently lie at the base of disagreements about values.     

言语想象的神经机制

言语想象不仅在大脑预处理机制方面起到重要的作用,还是目前脑机接口领域研究的热点。与正常言语产生过程相比,言语想象的理论模型、激活脑区、神经传导路径等均与其有较多相似之处。而言语障碍群体的言语想象、想象有意义的词语和句子时的脑神经机制与正常言语产生存在差异。鉴于人类言语系统的复杂性,言语想象的神经机制研究还面临一系列挑战,未来研究可在言语想象质量评价工具及神经解码范式、脑控制回路、激活通路、言语障碍群体的言语想象机制、词语和句子想象的脑神经信号等方面进一步探索,为有效提高脑机接口的识别率提供依据,为言语障碍群体的沟通提供便利。     

内隐记忆和内隐学习的整合研究趋向

内隐记忆和内隐学习代表了人类学习与记忆的无意识机制,它们打开了理解人类无意识奥妙的大门。从内隐记忆和内隐学习的诞生与实验室发展来看,二者似乎长期以来处在相对独立的位置。然而,随着研究的不断深入,走向整合已经成为不可抑制的趋向。该文旨在结合内隐记忆和内隐学习的定义、经验类似性、理论框架和实验研究等方面的证据,论述它们的整合必要以及已有的整合途径,促进研究对学习和记忆的无意识过程的全面把握     

疼痛恐惧对疼痛的影响及其认知机制

疼痛恐惧是把将要出现的疼痛刺激视为主要威胁而产生的一种恐惧,它会影响与疼痛相关的感知觉、注意、回避行为以及安慰剂止痛的效果.疼痛恐惧的认知模型主要有活动回避模型、恐惧-回避模型以及内感受性恐惧条件模型.未来的研究要进一步探究疼痛恐惧的认知机制,完善疼痛恐惧的认知模型并扩展疼痛恐惧的研究方法.