睡眠对恐惧学习的影响及其认知神经机制

睡眠问题可能会诱发恐惧相关情绪障碍(焦虑、创伤性应激障碍、恐怖症等),研究睡眠影响恐惧学习的认知神经机制,有助于增强对恐惧相关情绪障碍的预测、诊断和治疗。以往研究表明睡眠剥夺影响恐惧习得和消退主要是通过抑制vmPFC活动,阻碍其与杏仁核的功能连接,从而导致恐惧习得增强或是消退学习受损。进一步研究发现睡眠不同阶段对恐惧学习相关脑区有独特的影响:剥夺(缺乏)快速眼动睡眠会抑制vmPFC活动、增强杏仁核、海马激活,导致恐惧习得增强,消退学习受损,此外边缘皮层的功能连接减少破坏了记忆巩固(恐惧记忆和消退记忆);而慢波睡眠主要与海马变化有关,慢波睡眠期间进行目标记忆重激活可促进恐惧消退学习。未来研究需要增加睡眠影响恐惧泛化的神经机制研究、及昼夜节律中断对恐惧消退的影响,以及关注动物睡眠研究向人类睡眠研究转化中存在的问题。     

Teaching spontaneous responses to young children with autism

Using a multiple probe design across responses, we demonstrated the effectiveness of intensive intervention in establishing spontaneous verbal responses to 2 3-year-old children with autism with generalization to novel settings involving novel persons. Intervention involved discrete-trial instruction (i.e., repeated instructional opportunities presented in close proximity to high rates of reinforcement), specific prompts, and error correction. Spontaneous responses were defined as specific verbal utterances (e.g., the child says "bless you") following discriminative stimuli that did not involve explicit vocal directives (e.g., adult sneeze). The development of effective interventions to address the social-communicative needs of very young children with autism is discussed.     

OPTIMIZING LINKED PERCEPTUAL CLASS FORMATION AND TRANSFER OF FUNCTION

A linked perceptual class consists of two distinct perceptual classes, A′ and B′, the members of which have become related to each other. For example, a linked perceptual class might be composed of many pictures of a woman (one perceptual class) and the sounds of that woman's voice (the other perceptual class). In this case, any sound of the woman's voice would occasion the selection of any picture of the woman and vice versa. In addition, after learning to name the woman in the presence of one picture, that name would be uttered when presented with all of the images of the woman's face and all of the sounds of her voice. This study involved 15 participants and sought to (a) maximize the percentage of participants who formed linked perceptual classes, and (b) determine whether those classes acted as transfer networks, that is, whether the discriminative function of one class member would generalize to other members of the class and not to members of a different class. The rate of emergence of each linked perceptual class was maximized by establishing a single class‐linking conditional relation between the clearest member of one class used as a sample stimulus and the most ambiguous member of the other class used as a comparison stimulus. Class formation was demonstrated using the serial and programmed presentation of A′–B′ probes that consisted of untrained pairs of stimuli drawn from the A′ and B′ classes. Most participants showed immediate emergence of the two linked perceptual classes. The remaining participants showed delayed emergence following a second exposure to each originally error‐producing probes. Once the linked perceptual classes had emerged, a differential response to a specific member of one perceptual class generalized mostly or completely to the other members of that linked class and rarely, if ever, to members of the other linked class. Thus, generalization did not depend on the specific class members that had been used for discrimination training.     

效度概化：预测效度元分析的30年成果述评

效度概化是通过元分析技术对普遍化的预测效度的估计。元分析是研究效度概化问题的技术,是对具有“预测因子-效标”特征的相关数据进行定量综合的方法。效度概化促进了预测因子与效标之间关系的理论研究和应用研究,是应用心理学领域近30年（1977~2007）来最重要的进展之一。30年来的效度概化研究表明,认知能力测验、知识和技能测验、人格测验、结构化面试和评价中心技术等的预测效度具有鲁棒性、对应性和联合增值性     

A translational evaluation of renewal of inappropriate mealtime behavior

The term renewal describes the recurrence of previously extinguished behavior that occurs when the intervention context changes. Renewal has important clinical relevance as a paradigm for studying treatment relapse because context changes are necessary for generalization and maintenance of most intervention outcomes. The effects of context changes are particularly important during intervention for pediatric feeding disorders because children eat in a variety of contexts, and extinction is an empirically supported and often necessary intervention. Therefore, we used an ABA arrangement to test for renewal during intervention with 3 children diagnosed with a feeding disorder. The A phase was functional reinforcement of inappropriate mealtime behavior in a simulated home setting with the child's caregiver as feeder, B was function‐based extinction in a standard clinic setting with a therapist as feeder, and the return to the A phase was function‐based extinction in a simulated home setting with caregiver as feeder. Returning to Context A resulted in renewal of inappropriate mealtime behavior across children, despite the caregivers' continued implementation of function‐based extinction with high levels of integrity.     

Laboratory analogue investigation of defusion and reappraisal strategies in the context of symbolically generalized avoidance

The present study examined and compared the effects of 2 analogues of cognitive treatments—cognitive defusion and cognitive reappraisal—on symbolically generalized avoidance established using a basic behavioral laboratory paradigm. This back‐translation design contributes to the development and validation of principle‐based definitions of the applied constructs of defusion and reappraisal. Eighty‐eight participants first underwent basic laboratory procedures designed to establish symbolically generalized avoidance in response to an arbitrary stimulus (a nonsense word). Participants were then randomized to defusion, reappraisal, or control conditions. The response variables were (a) equivalence responding—indicative of the trained relational network and analogous to the cognitive content responsible for symbolic generalization—and (b) avoidance—the behavioral impact of symbolic generalization. A between‐groups analysis revealed that defusion and reappraisal significantly increased the odds of nonavoidance responding. Discrete‐time survival mediation analyses provided preliminary support for the classification of defusion as a functional context intervention and reappraisal as a relational context intervention.     

Effects of serial and concurrent training on receptive identification tasks: A Systematic replication

The current study compared the use of serial and concurrent methods to train multiple exemplars when teaching receptive language skills, providing a systematic replication of Wunderlich, Vollmer, Donaldson, and Phillips (2014). Five preschoolers diagnosed with developmental delays or autism spectrum disorders were taught to receptively identify letters or letter sounds. Subjects learned the target stimuli slightly faster in concurrent training and a high degree of generalization was obtained following both methods of training, indicating that both the serial and concurrent methods of training are efficient and effective instructional procedures.     

Using a stimulus correlated with reprimands to suppress automatically maintained eye poking

A functional analysis indicated that chronic eye poking exhibited by a woman with profound mental retardation persisted in the absence of social contingencies. We initiated a procedure in which a therapist delivered a punisher (mild reprimand) contingent on eye poking in the presence, but not the absence, of a neutral stimulus (wristbands). Subsequently, eye poking was suppressed when the participant wore the wristbands in novel environments without the reprimand contingency.     

Is the Self other to the self? Why does the numinosum feel like another? The relevance of Matte Blanco to our understanding of the unconscious

Using Ignacio Matte Blanco’s approach to the unconscious, this paper attempts to explain why the experience of the Self or the unconscious, for example in dreams, is difficult for the ego to understand. Matte Blanco believes that the logic of the unconscious is radically different from the logic of consciousness. The unconscious uses processes that Matte Blanco refers to as symmetry and generalization. Symmetry means that the converse of any relationship is identical to it, so that asymmetrical relationships are treated as if they were symmetrical. Generalization means that the unconscious treats any object as belonging to a larger class of objects that is a subset of an even larger class which is in turn a subset of a wider class ad infinitum. Hence Matte Blanco’s idea of the unconscious as infinite sets. These unconscious mechanisms, combined with the possibility that the unconscious has more dimensions than consciousness, contribute to the difficulty of understanding dreams, and help to explain why the Self is experienced as other to the ego.     

Being there on time: Reinforcer effects on timing and locating

In research on timing, reinforcers often are assumed to influence discrimination of elapsed time. We asked whether changes in choice used to measure timing arise because of joint control by elapsed time and reinforcers, rather than from the direct modification of control by elapsed time by reinforcers. Pigeons worked on a concurrent-choice task in which 1 response was 9 times more likely to produce a reinforcer, reversing between locations when 19 s had elapsed since the marker event. Across conditions, we manipulated the percentage of reinforcers arranged before the probability reversal from 5 to 95%. These changes in reinforcer percentages altered control by location-based elements of the contingency, but not by time-based elements. Choice was well described by a model that assumes that control by the contingency is weakened by generalization across the time and location of reinforcers, and that these generalizations become more likely at later times since a marker. These findings add to a growing body of research that suggests that reinforcers share the same function as other environmental events in determining how the environment controls behavior.