Cognitive epidemiology: With emphasis on untangling cognitive ability and socioeconomic status

This commentary touches on practical, public policy, and social science domains informed by cognitive epidemiology while pulling together common themes running through this important special issue. As is made clear in the contributions assembled here, and others (Deary, Whalley, & Starr, 2009; Gottfredson, 2004; Lubinski & Humphreys, 1992, 1997), social scientists and practitioners cannot afford to neglect cognitive ability when modeling epidemiological and health care phenomena. However, given the dominant concern about the confounding of general cognitive ability (GCA) and socioeconomic status (SES), and the extent to which SES is frequently seen as the primary cause of health disparities (while GCA is neglected as a possible influence in epidemiology and health psychology), some methodological applications for untangling the relative influences of GCA and SES are reviewed. In addition, cognitive epidemiology is placed in a broader context: Just as cognitive epidemiology facilitates an understanding of pathology (“at risk” populations, and ways to attenuate undesirable personal and social conditions), it may also enrich our understanding of optimal functioning (“at promise” populations, and ways to identify and nurture the human and social capital needed to develop innovations for saving lives, economies, and perhaps even our planet). Finally, while GCA is likely the most important dimension in the study of individual differences for modeling healthy behaviors and outcomes, other relatively independent dimensions of psychological diversity do add value (Krueger, Caspi, & Moffitt, 2000). For example, compliance has at least two psychological components: a “can do” competency component (ability) and a “will do” motivational component (conscientiousness). Ultimately, developing and modeling healthy behaviors, interpersonal environments, and medical maladies are best accomplished by teaming multiple dimensions of human individuality.     

Does a fitness factor contribute to the association between intelligence and health outcomes? Evidence from medical abnormality counts among 3654 US Veterans

We suggest that an over-arching ‘fitness factor’ (an index of general genetic quality that predicts survival and reproductive success) partially explains the observed associations between health outcomes and intelligence. As a proof of concept, we tested this idea in a sample of 3654 US Vietnam veterans aged 31–49 who completed five cognitive tests (from which we extracted a g factor), a detailed medical examination, and self-reports concerning lifestyle health risks (such as smoking and drinking). As indices of physical health, we aggregated ‘abnormality counts’ of physician-assessed neurological, morphological, and physiological abnormalities in eight categories: cranial nerves, motor nerves, peripheral sensory nerves, reflexes, head, body, skin condition, and urine tests. Since each abnormality was rare, the abnormality counts showed highly skewed, Poisson-like distributions. The correlation matrix amongst these eight abnormality counts formed only a weak positive manifold and thus yielded only a weak common factor. However, Poisson regressions showed that intelligence was a significant positive predictor of six of the eight abnormality counts, even controlling for diverse lifestyle covariates (age, obesity, combat and toxin exposure owing to service in Vietnam, and use of tobacco, alcohol, marijuana, and hard drugs). These results give preliminary support for the notion of a superordinate fitness factor above intelligence and physical health, which could be further investigated with direct genetic assessments of mutation load across individuals.     

食管癌研究的历史回顾和哲学思考

食管癌研究可分为病因学、发病机制和防治三个部分,涵盖了流行病学、生物化学、病理学、肿瘤学、分子生物学等多个学科。尽管两千多年前,我国学者以开始记载和描述食管癌,但直到近代特别是现代科学技术的进步才对食管癌有了系统的认识。回顾食管癌的研究史,不难看出,正确的研究方法和科学思路在揭示食管癌发病机制和控制食管癌发病率和死亡率中起关键的作用。辨证地剖析机体内部和外界环境之间的关系,人群研究和实验室研究,个体化局部治疗和全身综合治疗,基础和临床研究,传统方法和现代高科技的有机结合,国内外合作研究与小范围研究,研究者与食管癌患者之间的关系等方面的关系,是指导食管癌 研究的重要环节。     

Response to Michael Sells

In an era when lies and misrepresentations about historical events easily become firmly rooted, Michael Sells's discussion illustrates the importance of careful historical research as a moral enterprise. In addition to the skills of the historian, however, there is also room in this enterprise for those of the ethicist. In particular, I warn against confusing the truth or falsity of claims about one narrow historical period with larger questions about the moral meaning and significance of those claims. Illustrating this, I argue one cannot assess the legitimacy of competing nationhood claims solely on the basis of the deeds of specific actors. Nor should the actions of a single individual like the Grand Mufti of Jerusalem be converted into a totalizing claim about the rights of the Palestinian people.     

论《贞观政要》的官德思想

《贞观政要》不仅是一本"帝王学"著作,而且含有丰富的官德思想,其官德思想可以概括为"正己修德,修身治国"、"以史为鉴,居安思危"等方面,这些官德在贞观时期成为唐太宗君臣的为官之德,并被实践于贞观年间的治国理民之中,是"贞观之治"盛世得以出现的重要原因。《贞观政要》的官德思想继承了前代官德的优良传统,更对后世官箴的书写及官吏道德规范的制定提供了借鉴。     

日用类书涉医文献的历史特点及当代价值

日用类书自南宋末年诞生伊始就收录有医学文献,并伴随着时代发展而呈现出风貌迥异的文献特征。通过历史性与共时性两个视角,梳理总结日用类书涉医文献的三个历史特点：内容类型两极化、医学知识实用化及资料来源时效化。日用类书涉医文献作为中医药文化遗产的重要组成部分,不仅对中医文献学、中国医学史、出版文化史、通俗文化等领域的学术研究具有参考价值,而且对当今编纂入门医书和中医药科普书籍以及传承传播中医药文化,也具有现实的借鉴意义。

     

中国自杀未遂的流行特征及影响因素研究

自杀是一个严重的社会问题和公共卫生问题。但目前尚未完全了解自杀的影响因素以及预防自杀的方法。流行病学研究表明自杀未遂是自杀的重要预测因素,了解自杀未遂的特征以及影响因素将有助于减少自杀行为的发生。本文对自杀未遂的流行特征以及影响因素进行了综述。     

Sex Differences in Simple Visual Reaction Time: A Historical Meta-Analysis

To test the hypothesis that the magnitude of sex differences in simple visual reaction time (RT) has narrowed across time, a meta-analysis was conducted on 72 effect sizes derived from 21 studies (n=15,003) published over a 73-year period. The analysis provided strong evidence for the hypothesized change. In addition, the analysis indicated that the sex difference in RT was on average smaller with non-U.S. samples than with U.S. samples. No relation was found between the magnitude of the sex difference in RT and age or presence vs. absence of a warning signal. Two factors–-participation in fast-action sports and driving–-are proposed as having been responsible for the decrease in the magnitude of the sex differences in simple visual RT across time.     

The natural course of anxiety symptoms in early adolescence: factors related to persistence

Background and objectives: Anxiety disorders are the most common mental health problems during childhood and adolescence. This study examined the course of anxiety symptoms in early adolescents from the general population over three phases.

Design: Prospective cohort study.

Methods: Two hundred and forty-two participants (mean-age of 13.52) from a baseline sample of 1514 (mean-age of 10.23) were followed up three times. Of the 1514 children, those with emotional risk and controls without risk constituted the second-phase sample (n?=?562; mean-age of 11.25). The Screen for Child Anxiety Related Emotional Disorders-SCARED was administered in all three phases.

Results: Fifty-six percent and 32% of respondents showed total scores above the SCARED cutoff point at one and three years follow-up, respectively. Eight percent showed fluctuating symptoms. Fifty-five percent of respondents showed high scores for any subtype of anxiety over three years. Social phobia and generalized anxiety symptoms were the most prevalent and persistent. Participants with persistent separation anxiety showed the highest co-occurrence with symptoms of other psychopathological disorders. Participants with persistent anxiety showed lower academic performance. Being male was a protective factor against persistence.

Conclusions: The data support anxiety maintenance during early adolescence. Early adolescence is a critical period which may involve other serious academic, social, and family problems.     

论伊斯兰伦理道德形成初期的政治历史背景

伊斯兰教的兴起不但解决了穆斯林的信仰、伦理道德、行为规范、精神生活等问题,而且解决了民族命运、社会兴衰、阿拉伯半岛的统一等问题。本文试图通过对伊斯兰初创时期阿拉伯半岛外部形势和内部社会矛盾的深度剖析,探讨伊斯兰伦理道德形成初期的政治历史背景。