拓扑性质知觉的大脑半球功能不对称性研究

本文以视觉的拓扑知觉理论为指导进行大脑半球功能不对称性的研究。全文共有三个实验,考察了辨别扭扑性质差异和其它几何性质差异时大脑半球的功能不对称性．拓扑性质差异包括洞（封闭性）的差异和内外关系的差异．实验结果显示：对于右利手被试,辨别拓扑性质差异时,左半球有优势。辨别距离和朝向等几何性质差异时,右半球有优势或没有统计显著的大脑半球功能不对称性。     

Cerebral asymmetry in autonomic conditioning to facial expressions: Sex differences

In the present experiment, sex differences in hemispheric asymmetry during classical conditioning to emotional stimuli are reported. 125 subjects (62 females and 63 males) were shown a slide of a happy face in the right (or left) visual half field (VHF), and simultaneously a slide of an angry face in the left (or right) VHF. Eight groups were formed by the combination of male and female subjects; left and right VHF positions of the angry/happy faces; and the administration/omission of the shock unconditioned stimulus (UCS). Dependent measures were skin conductance responses recorded from both hands. The results during extinction showed a significant larger SCR magnitude to the shock compared to the no-shock groups only for the female subjects. CS position during conditioning was also important in revealing differential responding to either the happy or angry faces. A right hemisphere effect was found for the angry face CS for both the male and female subjects, however with a greater difference for the females.     

Hemispheric Differences in the Processing of Words Learned Early Versus Later in Childhood

The research investigated whether there are hemispheric differences in processing for words acquired early in childhood (early AoA) and words acquired later in childhood (late AoA). We hypothesized that because of recent evidence suggesting that there is a right hemisphere dominance in early childhood, early AoA words would be represented in the right hemisphere, and late AoA words would be represented in the left hemisphere. This hypothesis differs from an early view that late AoA words would be represented in the left hemisphere, and early AoA words would be represented in both hemispheres (Gazzaniga, 1974). We report two experiments using the divided visual field (DVF) technique. The results showed that there was a right visual field (RVF)/left hemisphere (LH) advantage only for late AoA words. For early AoA words, there was a left visual field (LVF)/right hemisphere advantage (RH). Implications for theories of hemispheric differences in word processing are discussed.     

The relationship between stress,hemispheric preference and decision making among managers

Abstract

Previous studies have shown important effects of stress on decision making (DM). In addition, individuals differ in their relative activation of the left and right hemispheres (hemispheric preference; HP), with possible implications for DM. This study tested the relationship between stress, HP and their interaction, with DM in managers. We included a sample of 114 managers from Israel, Italy and France. Stress was inversely and significantly related to DM thoroughness (r=?.333), left-HP (r=?.24) and was positively correlated with instinctiveness DM (r=.25; all p<.05). Importantly, a stress×HP interaction accounted for an additional and significant 9% of the variance in thoroughness, beyond their main effects, nationality and gender. In this interaction, only in right HP managers, but not in left HP managers, stress was inversely correlated with thoroughness. A stress×HP interaction was not found for instinctiveness. Theoretically, our results advise investigating both situational (stress) and personal or biological (HP) factors in the job stress field. Practically, it can guide stress specialists to whom to provide scarce counseling resources of stress management, to improve workers’ DM and well-being.     

三字字谜顿悟的时间进程和半球效应：一项ERP研究

运用事件相关电位ERPs技术, 采用猜谜任务范式, 从字谜问题解决中谜底“催化”所诱发顿悟的时间进程和半球差异两方面来探讨顿悟的认知神经机制。结果发现：在320~550ms内, “有顿悟”和“不理解”较“无顿悟”的ERP波形均有一个更大的负向偏移。在“有顿悟-无顿悟”和“不理解-无顿悟”差异波中, 该负成分的潜伏期约为380ms, 差异波的脑电峰值锁定在Cz点。半球主效应不显著, 但反应与半球交互效应显著, 其中“有顿悟”差异波的右半球平均波幅显著高于左半球和矢中部。结果表明：N380可能反映了顿悟中舍弃强外显意义而选择弱内在隐喻意义的认知抉择过程, 且右半球在“顿悟”中表现出优势效应。     

Neural correlates of successful and unsuccessful verbal memory encoding

Recent neuroimaging studies suggest that episodic memory encoding involves a network of neocortical structures which may act interdependently with medial temporal lobe (mTL) structures to promote the formation of durable memories, and that activation in certain structures is modulated according to task performance. Functional magnetic resonance imaging (fMRI) was used to determine the neural structures recruited during a verbal episodic encoding task and to examine the relationship between activation during encoding and subsequent recognition memory performance across subjects. Our results show performance-correlated activation during encoding both in neocortical and medial temporal structures. Neocortical activations associated with later successful and unsuccessful recognition memory were found to differ not only in magnitude, but also in hemispheric laterality. These performance-related hemispheric effects, which have not been previously reported, may correspond to between-subject differences in encoding strategy.     

Geometry,landmarks and the cerebral hemispheres: 2D spatial reorientation in split‐brain patients

A right‐hemispheric superiority in spatial encoding based on geometric cues has been largely documented in a variety of species, together with a left‐hemispheric specialization for encoding based on landmarks. In humans, hemispheric asymmetries for spatial encoding have been little explored. In this study, we compared a patient with a complete callosal resection (D.D.C.) and a patient with a wide callosal resection saving the splenium (A.P.), with healthy participants. In two 2D versions of the ‘reorientation task’, participants were asked to find the target corner of a rectangle‐shaped environment, by exploiting either geometric information alone or the combination of geometric and landmark information. In Experiment 1, the landmark consisted of a coloured side of the rectangle; in Experiment 2, this cue was replaced by a coloured disc located inside the rectangle. In both experiments, the rectangular shape ensured the geometric cue. D.D.C. was always unable to recall the target, whereas A.P. correctly solved the task when only the geometric information was available, without difference with respect to the controls. Importantly, the performance of A.P. did not differ from controls’ when the right hemisphere was tested with the landmark cues (the task being carried out using the left hand), whereas when the left hemisphere was tested (right‐hand session) his performance was worse than controls’ with the coloured side of the space, but it was better than controls’ with the coloured disc. The results are discussed comparing them with data collected on other species, and with theories of spatial processing.     

视觉表象产生的大脑半球专门化效应

采用Kosslyn单侧视野速示技术, 以英文字母图片为学习材料, 通过三个实验考察了视觉表象产生的大脑半球专门化效应。实验一提出在两种类型的视觉表象产生任务中, 有两种截然不同的加工起作用, 但却不能直接证实这两种不同加工机制的存在。实验二和实验三则进一步证实了两种表象产生任务具有不同的认知加工机制, 并表现出不同的大脑半球专门化效应。上述研究表明: 大脑两半球均参与产生视觉心理表象, 但分工不同, 并表现出不同的单侧化效应: 大脑左半球通过运用类别空间关系产生表象更有效, 大脑右半球运用数量空间关系产生表象更有效。结果进一步拓展了Kosslyn关于视觉空间关系加工的大脑半球专门化观点。     

Hemispheric Asymmetries: Attention to Visual and Auditory Primitives

A computational theory of hemispheric asymmetries in perception (double filtering by frequency) is described. Its central tenet is that the cerebral hemispheres first perform symmetric filtering of visual and auditory information. Functional hemispheric asymmetry arises from a second filtering stage (containing filters skewed in different directions in the two hemispheres). The first stage selects a range of task-relevant spatial or auditory frequencies from the absolute values. This range is passed to the asymmetric filters. In this way, the hemispheric difference becomes one of relative rather than absolute information. Behavioral deficits due to unilateral lesions in neurological patients and neuroimaging and electrophysiological measures in normal subjects implicate posterior cortex in these hemispheric differences.     

Functional magnetic resonance imaging of human cognitive processes

Functional magnetic resonance imaging (fMRI) is now widely accepted as a tool for analyzing human brain function. Since the realization of fMRI in the early 1990s, numerous reports have been published. In this paper, we present three studies. The first examined syntactic processing of Japanese sentences and the results prove that Broca's area is involved in the use of grammar. The second study compared binocular with monocular stereopsis. There were significant activations in the right inferior parietal lobe. The third study concerned the encoding and retrieval processes underlying face recognition. It revealed activations mainly in the right prefrontal areas, which is contrary to the hemispheric encoding and retrieval asymmetry (HERA) theory. fMRI will continue to play an important role in the analysis of human brain function.