肠易激综合征：罗马III标准与我国共识意见解读

肠易激综合征在我国的发病率逐年升高,2003年我国制定的IBS的共识意见已不适用,因此2007年我国肠易激综合征共识意见进行了重新修订,称为长沙共识意见。长沙共识意见借鉴了国际公认的罗马III标准,在IBS的诊断所需的时间,IBS的亚型分型等方面做了较大的修订。并强调了随诊在IBS诊断中的重要性。长沙共识意见同时指出罗马III标准是基于西方国家的研究资料制定的,并不完全适用于我国。我国在IBS的诊断中应结合国人的发病特点进行诊断。长沙共识意见在IBS的治疗方面就我国现状提出了治疗流程。     

微创技术在脑血管病诊治中的应用与存在的问题

脑血管病是危害人类健康的三大疾病之一.随着CT、,MRI、DSA等先进设备的应用,脑血管病的诊治水平进入一个新的阶段.显微手术、血管内栓塞、γ-刀或X-刀等很多微创技术不断应用于脑血管病的治疗.由于各地区发展不平衡,微创技术的应用尚存在不少问题.因此,必须积极稳妥地开展脑血管病诊治中的微创技术.     

“逆临床思维”与新型疾病发现方法的探讨

目的 初步总结发现新型疾病的方法和医学思维方式。方法 研究30余种疾病发现的过程。结果 新型疾病的发现过程和判断的思维方式似可初步总结为以下几个方面：（1）以疾病的异常特征为发现新型疾病的线索,包括流行病学、临床、实验室三个方面。（2）发现线索后从以上三个方面全面系统收集资料。（3）运用宏观思维寻找群体的共同特征,排除个体差异。（4）不仅收集与已知疾病相同的特征,而且还应注意与已知疾病不同的特征,然后综合分析判断。结论 发现新型疾病的方法与思维方式不同于经典的临床思维模式。     

Are General Practitioners Willing and Able to Provide Genetic Services for Common Diseases?

Primary care in the United Kingdom has been advocated as an optimal location for the provision of genetic services for common diseases. Little, however, is known about general practitioners' own views toward this suggestion or the possible demand for such services from patients. To assess general practitioners' attitudes to providing genetic services for common diseases, and to estimate the demand from patients for these services, we used a single-page postal questionnaire survey of all 359 general practitioners registered with the Oxfordshire Health Authority; 339 (94%) responded. These physicians reported that a mean 4.1 patients (95% CI, 3.3–4.9) out of every 1,000 consulting them were concerned about their own risk of a common disease associated with a diagnosis in a family member. Half of the general practitioners (95% CI, 45–56%) counseled about genetics in the last year. A majority of general practitioners accept the need to provide genetic services, but far fewer are competent to do so. Although 60% (95% CI, 55–65%) believed they should be involved with genetic screening for common diseases, only 29% (95% CI, 24–34%) felt sufficiently prepared to take family histories and draw pedigrees, and only 15% (95% CI, 11–19%) felt sufficiently prepared to counsel patients about their genetic test results. Given the necessary training and information, 63% (95% CI, 58–68%) and 64% (95% CI, 59–69%) were willing to provide these services. Even with training and information, not all would be willing to provide these services, and lack of time may be a major deterrent. Practice-enabling strategies, such as computerized aids in genetics, may be useful.     

The association between biopsychosocial factors and disability in a national health survey in South Africa

The association between psychosocial factors and disability is less clear. This study investigated the biological and psychosocial (employment and psychological distress) factors associated with level of disability in an adult sample in South Africa. Data were analysed from a cross-sectional survey among adults aged 18–64 (n = 4974). Multiple linear regression was used to investigate the associations of the selected variables with disability. The mean percentage score on the WHODAS scale of disability was 5.31% (95% CI: 4.74–5.88). Age (p < 0.001) and race (p = 0.0002) were significantly associated with disability, and history of stroke (β = 7.19, 95% CI: 3.19–11.20) and heart-related conditions (β = 2.08, 95% CI: [0.23–3.93) showed positive associations. Of the psychosocial variables, psychological distress (β = 10.49 [8.63–12.35]) showed a strong positive association while employment (?1.62 [?2.36 to ?0.88]) showed a negative association with disability. The association between demographic factors, medical conditions and increased disability confirms the findings in the literature. The finding that psychological distress is associated with increased disability has not been frequently reported. This study highlights specific psychosocial targets that may be usefully addressed by health policies and interventions in order to improve disability management.     

Topic-relevant cognition and empathic accuracy in laboratory discussions of safer sex

Abstract

The present study sought to identify some of the mechanisms that make safer sex such a difficult topic to talk about. Fifty six dating couples participated in a laboratory study in which the opposite-sex members of two pairs of couples engaged in two discussions of safer sex (or a control topic), each time with a different opposite-sex partner (their own dating partner or an opposite-sex stranger). The results indicated that discussions of safer sex evoke in dating partners a high level of perceived goal-incompatibility, difficulty maintaining one's focus on the topic, and difficulty in reading the other partner's thoughts and feelings. These reactions did not occur in response to the control topic. This initial demonstration study is important with respect to the processes it implicates, but further clarification is needed regarding the specific real-life conditions in which these processes do, and do not, occur.     

第三只眼睛看医学--对当代医学的反思和价值重审

当代医学的主体语境充满了对疾病的憎恶和排斥,限制了医学的视野。医学对人类的过度呵护,使人体“恃宠生矫”,导致人体生命内在素质的下降。因此,有必要对当代医学进行价值重审。与当代医学相配套的新的临床治疗体系“呼之难出”,使医学难以均衡发展,目前的当务之急是应尽快构建新的临床治疗体会。     

Patience mediates the relationship between mindfulness and pain in patients with cardiovascular diseases

The aim of the present study was to investigate the mediating role of patience in the relationship between mindfulness and pain among patients with cardiovascular disease. A cross-sectional design was employed. One hundred and ten patients with cardiovascular diseases were conveniently sampled from the clinic of Imam Reza in the city of Shiraz in Iran. Participants completed self-report measures of mindfulness, patience, and pain. Structural equation modeling was performed with Amos 16.0. Results indicated that mindfulness and patience had a significant inverse relationship with pain. There was also a significant positive relationship between patience and mindfulness. Estimated indirect effects showed that patience partly mediated the relationship between mindfulness and pain. These results show that among cardiovascular patients, increases in mindfulness are associated with reductions in pain as a function of increased patience. Therefore, patience is plausibly a key mechanism for understanding the impact of mindfulness on pain reduction.     

Nasal diseases and psychological distress

A high rate of ENT doctors were murdered by nasal disordered patients in China recently. It is obviously important and urgent to find out whether there is any potential relationship between nasal diseases (ND) and psychological distress that might contribute to violent behavior. For this purpose, we carried out this literature review. There is a complex relationship between ND and psychiatric distress, which is mainly considered as a bidirectional causal relationship with other controversy opinions. However, most of the previous studies were found to be focused on allergic rhinitis and chronic rhinosinusitis, while reports about other ND were rare. Further study is still needed to uncover the secret aspects in this field, and more attentions need to be paid to other ND.