Protection of animal research subjects

The use of experimental animals, mostly rodents, in biomedical research and especially in oncology and immunology should be acknowledged with respect, recognizing the contribution of animal experimentation in the fascinating scientific progress in these disciplines of research. It is an obligation of the investigator to justify the scientific and ethical aspects of each study requiring the use of animals. The international guiding principles for using animals in biomedical research are well defined and have been distributed worldwide by the International Council for Laboratory Animal Science (ICLAS) since 1956, when this Organization was founded. In Poland the ICLAS philosophy and principles are highly respected and were implemented firstly by the members of the Commission on Biology of Experimental Animals appointed in 1962 by the Department of Medical Science of the Polish Academy of Science in Warsaw. Animal Protection Acts, first proclaimed in 1928 were gradually modified and improved. Actual legislation (enacted in 1997, 2003 and 2005) is consistent with EU Directives (86/609/EEC) and follows the internationally recommended principles that include ICLAS guidelines concerning animal welfare and care condition in biomedical research. The problem of “alternative methods” is briefly discussed. Dr. Donald Boisvert, CCAC — Canadian Council on Animal Care A lecture on the subject of this paper was presented at the 6th International Bioethics Conference entitled ‘The Responsible Conduct of Basic and Clinical Research’, held in Warsaw, Poland, 3–4 June 2005. The author is the National Representative of Polish Academy of Science to the International Council for Laboratory Animal Science (ICLAS) and a Member of the ICLAS Governing Board.     

An analysis of modifications to the three-step guided compliance procedure necessary to achieve compliance among preschool children

After a 3‐step guided compliance procedure (vocal prompt, vocal plus model prompt, vocal prompt plus physical guidance) did not increase compliance, we evaluated 2 modifications with 4 preschool children who exhibited noncompliance. The first modification consisted of omission of the model prompt, and the second modification consisted of omitting the model prompt and decreasing the interprompt interval from 10 s to 5 s. Each of the modifications effectively increased compliance for 1 participant. For the remaining 2 participants, neither modification was effective; differential reinforcement in the form of contingent access to a preferred edible item was necessary to increase compliance. Problem behavior varied across participants, but was generally higher during guided compliance conditions and lower during differential reinforcement conditions.     

Career guidance and therapeutic counselling: sharing ‘what works’ in practice with young people

Many young people in the UK and across the world, where austerity measures are biting deep, find themselves at a time of crisis and uncertainty in their lives. The assumptions previously held of clear and straightforward career paths are being challenged and ‘career’ has come to mean more than simply ‘work’ or ‘employment’. This has implications for career practice, where career advisers are engaging with a range of complex issues in their guidance interactions with clients. This article draws on research undertaken with therapeutic counsellors into ‘what works’ when counselling young people. It offers career practitioners the opportunity to reflect on four key emerging themes and to consider how the discipline of therapeutic counselling might inform guidance practice.     

Career guidance of adolescents in their sociocultural development and modern technologies

RelevanceThe creation of a system of work with schoolchildren focused on choosing a profession taking into account possible success in a specific professional field is relevant.AimThe article is aimed at analysis of the situation of adolescents’ susceptibility to such guidance basing on different components.Materials and MethodsThe methodology of creating and implementing a special course is focused on the formation of basic elements of readiness for professional activities.ResultsThe authors of the study developed long-term projects that are considered to improve socio-economic development and increase the quality of work in various industries and at the personal level–socio-cultural development and socialization of adolescents.ConclusionThe career guidance for adolescents should include information about the means of communication. The development of the definition of technological means to provide information on the choice of profession is a significant part of the career guidance program.     

The Medium of Haptic Perception: A Tensegrity Hypothesis

ABSTRACT

For any given animal, the sources of mechanical disturbances inducing tissue deformation define environment from the perspective of the animal's haptic perceptual system. The system's achievements include perceiving the body, attachments to the body, and the surfaces and substances adjacent to the body. Among the perceptual systems, it stands alone in having no defined medium. There is no articulated functional equivalent to air and water, the media that make possible the energy transmissions and diffusions underpinning the other perceptual systems. To identify the haptic system's medium the authors focus on connective tissue and the conjunction of muscular, connective tissue net, and skeletal (MCS) as the body's proper characterization. The challenge is a biophysical formulation of MCS as a continuum that, similar to air and water, is homogeneous and isotropic. The authors hypothesized a multifractal tensegrity (MFT) with the shape and stability of the constituents of each scale, from individual cell to whole body, derivative of continuous tension and discontinuous compression. Each component tensegrity of MFT is an adjustive-receptive unit, and the array of tensions in MFT is information about MCS. The authors extend the MFT hypothesis to body-brain linkages, and to limb perception phenomena attendant to amputation, vibration, anesthesia, neuropathy, and microgravity.     

Narrative identity: writing the self in career learning

We propose that writing can be employed to foster the kind of career learning required in the twenty-first century. The article offers insights into how writing exercises and approaches can be applied to help students construct their career stories in a way that allows them to engage in a dialogical learning process and work in a self-directed way. Creative, expressive and reflective writing practices are described and parallels are drawn between these and existing practices and theories in narrative career counselling. Key exercises in graduate courses for writing for personal development are discussed and a theoretical explanation is given as to why a particular order of approaches and exercises works best to promote career learning.     

Computer-based written emotional disclosure: the effects of advance or real-time guidance and moderation by Big 5 personality traits

Standard written emotional disclosure (WED) about stress, which is private and unguided, yields small health benefits. The effect of providing individualized guidance to writers may enhance WED, but has not been tested. This trial of computer-based WED compared two novel therapist-guided forms of WED – advance guidance (before sessions) and real-time guidance (during sessions, through instant messaging) – to both standard WED and control writing; it also tested Big 5 personality traits as moderators of guided WED. Young adult participants (n = 163) with unresolved stressful experiences were randomized to conditions, had three, 30-min computer-based writing sessions, and were reassessed six weeks later. Contrary to hypotheses, real-time guidance WED had poorer outcomes than the other conditions on several measures, and advance guidance WED also showed some poorer outcomes. Moderator analyses revealed that participants with low baseline agreeableness, low extraversion, or high conscientiousness had relatively poor responses to guidance. We conclude that providing guidance for WED, especially in real-time, may interfere with emotional processing of unresolved stress, particularly for people whose personalities have poor fit with this interactive form of WED.     

Work-related counselling-a psychodynamic approach

Abstract

The paper sets out to stimulate interest in counsellors and therapists about the unconscious relationships which people form with their work, through describing and analysing what goes on in work-related counselling with a psychodynamic approach. The author draws on twenty-five years of experience to reflect on the changing nature of what was once termed ‘vocational guidance', and offers some short case studies, as examples of ways in which a person's world of work can become intertwined with their internal world in a confusing and disabling way. The core concepts and techniques which have evolved are identified and discussed; attention is directed particularly to the importance of the client's expectations, die effect of time limitation, the place of work in the whole life, and dealing with transference.     

The interplay of bottom-up and top-down mechanisms in visual guidance during object naming

An ongoing issue in visual cognition concerns the roles played by low- and high-level information in guiding visual attention, with current research remaining inconclusive about the interaction between the two. In this study, we bring fresh evidence into this long-standing debate by investigating visual saliency and contextual congruency during object naming (Experiment 1), a task in which visual processing interacts with language processing. We then compare the results of this experiment to data of a memorization task using the same stimuli (Experiment 2). In Experiment 1, we find that both saliency and congruency influence visual and naming responses and interact with linguistic factors. In particular, incongruent objects are fixated later and less often than congruent ones. However, saliency is a significant predictor of object naming, with salient objects being named earlier in a trial. Furthermore, the saliency and congruency of a named object interact with the lexical frequency of the associated word and mediate the time-course of fixations at naming. In Experiment 2, we find a similar overall pattern in the eye-movement responses, but only the congruency of the target is a significant predictor, with incongruent targets fixated less often than congruent targets. Crucially, this finding contrasts with claims in the literature that incongruent objects are more informative than congruent objects by deviating from scene context and hence need a longer processing. Overall, this study suggests that different sources of information are interactively used to guide visual attention on the targets to be named and raises new questions for existing theories of visual attention.