乳腺癌患者“创伤后成长”的研究进展

近年来,乳腺癌的发病率不断上升,乳腺癌已逐渐成为危害女性健康的首位恶性肿瘤。手术给患者的身心带来很大伤害,但研究者发现,在与乳腺癌这一疾病做斗争的过程中患者会产生一种正向的心理变化,这就是积极心理学领域研究的创伤后成长。本文从创伤后成长内涵、国内外研究现状、测量工具、影响因素、干预方法等几方面对乳腺癌创伤后成长研究现状进行文献综述,为乳腺癌患者心理护理提供依据。     

EGFR突变NSCLC二线TKIs治疗优化选择

恶性肿瘤的治疗已经进入驱动基因指导下的个体治疗时代,肺癌患者应该进行多基因检测,特别是表皮生长因子受体（EGFR）基因突变。EGFR基因突变的非小细胞肺癌（NSCLC）患者,如果一线接受了化疗,二线应该选择表皮生长因子受体一酪氨酸酶抑制剂（EGFR—TKIs）。EGFR基因突变的NSCLC患者一线EGFR—TKIs治疗失败后,二线治疗应该是个体化合理选择,包括局部放疗、化疗和继续EGFR—TKIs。目前一代和二代EGFR—TKIs药物之间未见到显著疗效差别。第三代EGFR—TKIs是目前的EGFR—TKIs耐药后的最有希望的选择,特别是针对T790M突变耐药。     

IGFBP-2及IGFBP-6在结直肠癌中的表达及意义

研究胰岛素样生长因子结合蛋白2（IGFBP-2）及胰岛素样生长因子结合蛋白6（IGFBP-6）在结直肠癌中的表达及临床意义。采用免疫组织化学法及RT-PCR方法检测结直肠癌、结直肠腺瘤及癌旁正常黏膜组织中IGFBP-2及IGFBP-6的蛋白及mRNA的表达情况,结合临床病理资料进行统计学分析。IGFBP-2及IGFBP-6蛋白的阳性表达及mRNA的表达量在三组组织中均存在异常表达情况,且差异有明显的统计学意义（P〈0.05）,在结直肠癌组IGFBP-2、IGFBP-6的阳性表达在肿瘤浸润深度、有无淋巴结转移及Duke＇s分期存在差异,有明显的统计学差异（P〈0.05）。临床可以把二者作为结直肠癌诊断及预后的早期预测指标。     

PTSD,Posttraumatic Growth,and Coping Among Ultra-Orthodox Jewish Battered Women in Israel

This study examined the association between posttraumatic stress (PTS) symptoms, posttraumatic growth (PTG), and coping styles in a very unique and difficult-to-access Jewish ultra-Orthodox population. The study was conducted with 88 women who spent time in the only shelter in Israel for battered women from the ultra-Orthodox Jewish community; data were collected almost 6 years on average after they left the shelter. No association was found between PTS symptoms and PTG. In addition, coping style was not found to have an indirect effect on the relationship between these variables. The theoretical and clinical implications of these findings are discussed.     

Failing safely: Increasing theology and religious studies students’ resilience and academic confidence via risk‐taking in formative assessment

Students increasingly appear anxious, risk‐averse, and worried about getting things “wrong.” They may appear to lack intellectual curiosity, and be unwilling to engage in independent study. This essay explores how teaching and assessment in theology and religious studies might help students learn to take intellectual risks, and increase their resilience. One approach is to encourage students to experiment and “fail safely,” to increase their confidence that they understand what is expected of them, and to help them begin to understand learning as more broadly formational, not always directed toward a grade. I suggest three strategies: more formative assessment; a stronger narrative about the purpose of formative assessment; and an appeal to values, virtue, and the cultivation of character. Via these approaches, students might be encouraged to understand assessment in less utilitarian terms and increase their resilience for a world characterized by volatility, uncertainty, complexity, and ambiguity, prepared both critically and dispositionally to thrive and contribute positively to society.     

Emotional intelligence and personal growth initiative effects on subjective happiness among university students

This study examined emotional intelligence and personal growth initiative influences on the level of subjective happiness among university students in Ghana. Two hundred and sixty undergraduate students were participants (female = 69.8%; mean age = 21.72 years, SD = 3.61 years). They responded to measures of emotional intelligence, personal growth initiative, and subjective happiness. After controlling for their demographic characteristics, and following hierarchical regression analysis, results indicate emotional intelligence and intentional behaviour domain of personal growth to predict students’ level of subjective happiness. These findings suggest that students’ ability to manage and utilise their emotions, as well as their personal growth initiative contribute significantly to their level of happiness.     

Cross-Cultural Challenges to the Construct “Posttraumatic Growth”

Responses of individuals to traumatic events are varied. Traumatic events can lead to positive transformations that are known as posttraumatic growth (PTG). Most of the empirical studies of PTG have been addressed from a Western perspective. Theoretically, the concept appears to be cross-culturally valid, but there has been a fundamental deficiency in operationalizing the concept in regard to cultures that are non-Western. Cultural elements play an important role in influencing the behavior of individuals in the aftermath of trauma. Hence, it is important to conceptualize and measure PTG in the framework of the culture to which the individual belongs. The effects of culture come from both the immediate culture (proximal) and the broader (distal) sources that impact the nature of rumination, cognitive strategies, and the process of growth. This paper addresses various cross-cultural challenges to the construct PTG such as emic versus etic perspectives on PTG, proximate and distal influences of culture on PTG, specific cultural influences on rumination, cognitive strategies, and growth, cultural bias inherent in theories of PTG, and measurement issues of PTG across cultures.     

The longitudinal association between internalizing symptoms and academic achievement among immigrant and non‐immigrant children in Norway

The aim of this study was to explore the longitudinal relation between internalizing symptoms and academic achievement, as two processes of children and youth development, among children in Norway, and whether having an immigrant background moderated this association. Data collected from 4,458 students in Norway in four waves over three years were analyzed with multi‐group latent growth curve modeling (LGM ). Results showed that internalizing symptoms level remained unchanged over time both for immigrant and non‐immigrant children, while levels of academic achievement increased only for children of immigrants with both parents born outside of Norway. Further analyses supported a reciprocal relation between internalizing symptoms and academic achievement and revealed that the initial level of academic achievement predicted the rate of change in internalizing symptoms over time, but not vice versa. Moreover, immigrant background did not moderate the associations in the model, however, children of immigrants with both parents born abroad initially had lower levels of academic achievement, but showed an increase in academic achievement, compared to their non‐immigrant peers as well as to peers with one native‐born parent after controlling for gender and their grade at the first observation. The implications for policy and practice were discussed.     

Latent Growth Curve and Repeated Measures ANOVA Contrasts: What the Models are Telling You

The relationship between the latent growth curve and repeated measures ANOVA models is often misunderstood. Although a number of investigators have looked into the similarities and differences among these models, a cursory reading of the literature can give the impression that they are very different models. Here we show that each model represents a set of contrasts on the occasion means. We demonstrate that the fixed effects parameters of the estimated basis vector latent growth curve model are merely a transformation of the repeated measures ANOVA fixed effects parameters. We further show that differences in fit in models that estimate the same means structure can be due to the different error covariance structures implied by the model. We show these relationships both algebraically and through using data from a simulation.     

死亡心理:外部防御还是内在成长?

对西方主要的死亡心理研究进行了回顾和比较分析,不同的死亡心理研究在研究传统、研究对象和研究方法方面存在差异。但是根据研究的侧重点,可以总结出死亡心理的核心内涵:外部防御和内在成长。对死亡的抽象认知产生死亡焦虑,死亡焦虑产生死亡恐惧、自我保护、外在价值导向等外部防御反应;对死亡的具体认知产生死亡反省,死亡反省产生死亡接受、亲社会动机和行为、内在价值导向等内在成长反应。作者以死亡心理的两类反应为框架,综述了近5年来新的研究证据,并对该领域当前研究的局限和未来研究方向进行了分析。