It's not all in the face: reduced face visibility does not modulate social segmentation

Humans rely on social information to parse environmental content into social and nonsocial events. Here, we assessed if information conveyed by faces was necessary for this process. We asked participants to view a video clip depicting a social interaction and mark social and nonsocial events while actors’ faces were either visible or blurred. Keypress and eye-movement data were collected. Participants consistently identified social and nonsocial event boundaries independently of face availability, with greater agreement and less variability in keypresses for social relative to nonsocial events. Eye-tracking revealed that participants attended more to actors’ faces when they were visible and more to bodies when faces were blurred. Thus, face information is not necessary for social segmentation, which appears to be a flexible process that depends on a range of information conveyed by both faces and bodies.     

Parental coping socialization is associated with healthy and anxious early‐adolescents’ neural and real‐world response to threat

The ways parents socialize their adolescents to cope with anxiety (i.e., coping socialization) may be instrumental in the development of threat processing and coping responses. Coping socialization may be important for anxious adolescents, as they show altered neural threat processing and over reliance on disengaged coping (e.g., avoidance and distraction), which can maintain anxiety. We investigated whether coping socialization was associated with anxious and healthy adolescents’ neural response to threat, and whether neural activation was associated with disengaged coping. Healthy and clinically anxious early adolescents (N = 120; M = 11.46 years; 71 girls) and a parent engaged in interactions designed to elicit adolescents’ anxiety and parents’ response to adolescents’ anxiety. Parents’ use of reframing and problem solving statements was coded to measure coping socialization. In a subsequent visit, we assessed adolescents’ neural response to threat words during a neuroimaging task. Adolescents’ disengaged coping was measured using ecological momentary assessment. Greater coping socialization was associated with lower anterior insula and perigenual cingulate activation in healthy adolescents and higher activation in anxious adolescents. Coping socialization was indirectly associated with less disengaged coping for anxious adolescents through neural activation. Findings suggest that associations between coping socialization and early adolescents’ neural response to threat differ depending on clinical status and have implications for anxious adolescents’ coping.     

Do attentional capacities and processing speed mediate the effect of age on executive functioning?

The executive processes are well known to decline with age, and similar data also exists for attentional capacities and processing speed. Therefore, we investigated whether these two last nonexecutive variables would mediate the effect of age on executive functions (inhibition, shifting, updating, and dual-task coordination). We administered a large battery of executive, attentional and processing speed tasks to 104 young and 71 older people, and we performed mediation analyses with variables showing a significant age effect. All executive and processing speed measures showed age-related effects while only the visual scanning task performance (selective attention) was explained by age when controlled for gender and educational level. Regarding mediation analyses, visual scanning partially mediated the age effect on updating while processing speed partially mediated the age effect on shifting, updating and dual-task coordination. In a more exploratory way, inhibition was also found to partially mediate the effect of age on the three other executive functions. Attention did not greatly influence executive functioning in aging while, in agreement with the literature, processing speed seems to be a major mediator of the age effect on these processes. Interestingly, the global pattern of results seems also to indicate an influence of inhibition but further studies are needed to confirm the role of that variable as a mediator and its relative importance by comparison with processing speed.     

Examining HPA-axis functioning as a mediator of the relationship between depression and cognition across the adult lifespan

Altered HPA-axis functioning is a hypothesized mechanism for worsened cognition in depression. The current study examines the indirect effects of depression on processing speed, executive functioning, and memory as a function of the HPA-axis. 38 individuals with a depression diagnosis and 50 healthy controls (HCs) aged 18–86 underwent neuropsychological testing and at-home diurnal salivary cortisol collection. Depression was assessed via structured clinical interviews and rating scales. Cognitive composite scores were derived from factor analysis. Daytime cortisol exposure was estimated using area under the curve (AUC). Depression was associated with higher cortisol levels and slower processing speed . A significant suppression effect of AUC was present on the relationship between depression and processing speed. Limitations include the cross-sectional design and limited sample heterogeneity. Though poorly modulated HPA-axis is one proposed mechanism of cognitive alterations in depression, our results did not support this conclusion for processing speed. Alternative mechanisms should be considered to inform interventions to target cognitive alterations in depression.     

A performance comparison between shallow and deeper neural networks supervised classification of tomosynthesis breast lesions images

Computer Aided Decision (CAD) systems, based on 3D tomosynthesis imaging, could support radiologists in classifying different kinds of breast lesions and then improve the diagnosis of breast cancer (BC) with a lower X-ray dose than in Computer Tomography (CT) systems.In previous work, several Convolutional Neural Network (CNN) architectures were evaluated to discriminate four different classes of lesions considering high-resolution images automatically segmented: (a) irregular opacity lesions, (b) regular opacity lesions, (c) stellar opacity lesions and (d) no-lesions. In this paper, instead, we use the same previously extracted relevant Regions of Interest (ROIs) containing the lesions, but we propose and evaluate two different approaches to better discriminate among the four classes.In this work, we evaluate and compare the performance of two different frameworks both considering supervised classifiers topologies. The first framework is feature-based, and consider morphological and textural hand-crafted features, extracted from each ROI, as input to optimised Artificial Neural Network (ANN) classifiers. The second framework, instead, considers non-neural classifiers based on automatically computed features evaluating the classification performance extracting several sets of features using different Convolutional Neural Network models.Final results show that the second framework, based on features computed automatically by CNN architectures performs better than the first approach, in terms of accuracy, specificity, and sensitivity.     

How Payment for Research Participation Can Be Coercive

The idea that payment for research participation can be coercive appears widespread among research ethics committee members, researchers, and regulatory bodies. Yet analysis of the concept of coercion by philosophers and bioethicists has mostly concluded that payment does not coerce, because coercion necessarily involves threats, not offers. In this article we aim to resolve this disagreement by distinguishing between two distinct but overlapping concepts of coercion. Consent-undermining coercion marks out certain actions as impermissible and certain agreements as unenforceable. By contrast, coercion as subjection indicates a way in which someone’s interests can be partially set back in virtue of being subject to another’s foreign will. While offers of payment do not normally constitute consent-undermining coercion, they do sometimes constitute coercion as subjection. We offer an analysis of coercion as subjection and propose three possible practical responses to worries about the coerciveness of payment.     

药物成瘾者决策缺陷的特征、机制及干预

药物成瘾者存在决策缺陷, 并表现出冲动性、风险寻求、奖赏失调、躯体内感信号缺失等特征。神经影像学研究表明药物滥用导致成瘾者背外侧前额皮层、前扣带回、眶额叶皮层、腹内侧前额皮层、杏仁核、脑岛等脑区受损, 这些损伤是引发其决策缺陷的主要原因。认知训练有利于提高个体的决策能力, 如目标管理训练和正念冥想等可以增强个体工作记忆、促进自我觉察和以目标为导向的行为; 而非侵入性脑刺激则可以直接改变与成瘾者决策相关脑区的激活状态, 从而提升与决策相关的认知功能。总体而言, 未来认知训练和非侵入性脑刺激在成瘾干预方面仍有广阔的拓展空间。     

书写对阅读的影响——来自传统书写与电脑打字的证据

书写和阅读是在文字的基础上发展起来的, 二者存在共享的神经网络。书写能影响阅读, 阅读不仅依靠视觉加工, 还依赖书写运动表征。不同书写方式对阅读的影响不同, 传统书写对阅读有促进作用, 电脑打字对阅读产生了一定的消极影响。对汉字来说, 传统书写能加强汉字的正字法表征, 促进汉字阅读; 电脑打字对汉字阅读的影响尚无一致结论。未来研究可以考察传统书写与电脑打字神经机制的差异, 以及电脑打字对汉字认知加工的影响及神经机制。     

音乐的神经美学：从审美反应到神经基础

近年来, 随着音乐的神经科学与神经美学的发展, 逐渐形成一个新的研究领域, 即音乐的神经美学。这一研究领域关注音乐审美的心理过程和神经机制, 将注意力集中于音乐审美活动中的感知、认知和情感解释。音乐审美加工引起了相应的审美反应, 其中有三种音乐审美反应得到研究者更多的关注, 即音乐审美情绪、判断与偏好。研究者围绕这三种反应, 对音乐审美反应的知觉、认知、情绪加工和影响因素以及其神经机制展开研究。这些研究为我们理解音乐和美学的行为与神经机制提供了经验性证据。     

增龄性联结记忆损伤及其影响因素

老年人的联结记忆随年龄增长而出现普遍损伤, 这种增龄性联结记忆损伤究竟是因捆绑功能受损导致的特定损伤还是因整体认知机能受损导致的信息表征能力的整体损伤, 还存有争论。以Naveh-Benjamin (2000)的联结损伤假说(ADH)为代表的特定损伤观认为, 增龄性联结记忆损伤与老年人捆绑不同项目和提取这些捆绑的特定加工过程的损伤有关; 而以Benjamin (2010)的DRYAD模型为代表的整体损伤观则认为, 增龄性联结记忆损伤与老年人因老化而导致的记忆保持精度的整体损伤有关。二者在基本观点、实验支持及存在问题上各有侧重。此外, 影响增龄性联结损伤的因素还可大致分为刺激信息特性、被试主体特点两方面。同时强调未来研究不仅要关注老年人联结损伤的认知机制和影响因素, 更应关注其实际应用和临床指导价值。