Modern Advances in Genetic Testing: Ethical Challenges and Training Implications for Current and Future Psychologists

The ethical implications for psychological practice of genetic testing are largely unexplored. Predictive testing can have a significant impact on health and well-being, and increasing numbers of individuals with knowledge of their risk for various disorders are likely to present for psychotherapy. In addition, more people will struggle with the decision of whether to obtain information regarding their genetic material. Psychologists will need to have the appropriate knowledge and clinical skills to effectively counsel this population. This article highlights the relevant ethical issues surrounding psychological treatment of individuals pursuing or considering undergoing genetic testing. These issues are extended to psychologists working in research, education, and policy domains. Recommendations for graduate training programs to facilitate current and future practitioner competence are also discussed.     

Do temporal processes underlie left hemisphere dominance in speech perception?

It is not unusual to find it stated as a fact that the left hemisphere is specialized for the processing of rapid, or temporal aspects of sound, and that the dominance of the left hemisphere in the perception of speech can be a consequence of this specialization. In this review we explore the history of this claim and assess the weight of this assumption. We will demonstrate that instead of a supposed sensitivity of the left temporal lobe for the acoustic properties of speech, it is the right temporal lobe which shows a marked preference for certain properties of sounds, for example longer durations, or variations in pitch. We finish by outlining some alternative factors that contribute to the left lateralization of speech perception.     

Functional Neuroimaging and the Law: Trends and Directions for Future Scholarship

Under the umbrella of the burgeoning neurotransdisciplines, scholars are using the principles and research methodologies of their primary and secondary fields to examine developments in neuroimaging, neuromodulation and psychopharmacology. The path for advanced scholarship at the intersection of law and neuroscience may clear if work across the disciplines is collected and reviewed and outstanding and debated issues are identified and clarified. In this article, I organize, examine and refine a narrow class of the burgeoning neurotransdiscipline scholarship; that is, scholarship at the interface of law and functional magnetic resonance imaging (fMRI).     

斑马鱼模式动物在神经功能环路研究中的应用

斑马鱼是发育、遗传以及药物发现研究中常用的模式动物.作为重要的脊椎动物模式系统之一,斑马鱼与人类基因有高度同源性,中枢神经系统也与哺乳动物相似.近来,斑马鱼在神经科学研究以及生理心理学相关问题的研究中的应用日益广泛.研究者们对斑马鱼幼鱼及成鱼的行为表现及行为发育开展了多方面的研究.基于斑马鱼模式动物的特点及优势,遗传突变和药物筛选在对动物行为表现的分子机制的研究中起到重要的推动作用.     

练习促进内隐策略生成：其发生过程及应用特点

本研究通过设置隐含算术策略的问题情境,比较不同顺序和设置条件的进程段行为反应和ERP数据差异,考察被试在不断练习条件下对隐含策略的习得过程及迁移应用特点。结果：被试在对隐含策略无意识的情况下,第1-4练习进程段的反应时、错误率显著低于第5进程段（探测段）。同时,不同进程段诱发的部分ERPs特征也呈现有规律的变化。结论：在存在隐含策略的算术策略任务情境中,通过练习人们可以在无意识情况下逐渐生成内隐策略,诱发的ERP成分P200、N400s可以部分地反映其生成过程。已生成的内隐策略,能部分地应用到相应的新情境中。     

Illness representations,knowledge and motivation to perform presymptomatic testing for late-onset genetic diseases

This study addresses the relation between illness representations, knowledge and motivation to perform the presymptomatic testing (PST) of subjects at-risk for Familial Amyloydotic Polyneuropathy (FAP), Huntington’s disease (HD) and Machado–Joseph disease (MJD), compared with subjects at-risk for Hereditary Hemochromatosis (HH). The sample comprised a clinical group of 213 subjects at genetic risk for FAP, HD and MJD, and a comparison group of 31 subjects at genetic risk for HH, that answered three open-ended questions relating illness representations, knowledge about the disease, and motivation to perform PST. People at-risk for FAP, HD and MJD use more metaphors, make more references to the family, are more concerned with the future and feel more out of curiosity and to learn, than for HH. These subjects at-risk correspond to the profile of somatic individual or personhood, wherein the unsubjectivation of the disease can function as a coping mechanism.     

Genetic and environmental structures of personality: A cluster-analysis approach

A cluster analysis was carried out on within-individual and cross-pair correlations among personality questionnaire items for 654 monozygotic and 648 dizygotic twin pairs in an initial sample, and 649 and 649 pairs in a cross-validation sample. The data were from adult Australian twins who had responded in a mail questionnaire to 110 items from two personality inventories. Clustering based on genetic correlations or on unshared environmental correlations among items led to three very similar cross-validated clusters, labeled Emotional, Confident, and Reserved. Unshared environment provided several additional cross-validated clusters. Clusters based on shared environment, on the other hand, failed to cross-validate or to correspond to the clusters from the other two sources.     

Dissociating Medial Temporal and Striatal Memory Systems With a Same/Different Matching Task: Evidence for Two Neural Systems in Human Recognition

The medial temporal lobe and striatum have both been implicated as brain substrates of memory and learning. Here, we show dissociation between these two memory systems using a same/different matching task, in which subjects judged whether four-letter strings were the same or different. Different RT was determined by the left-to-right location of the first letter different between the study and test string, consistent with a left-to-right comparison of the study and test strings, terminating when a difference was found. This comparison process results in same responses being slower than different responses. Nevertheless, same responses were faster than different responses. Same responses were associated with hippocampus activation. Different responses were associated with both caudate and hippocampus activation. These findings are consistent with the dual-system hypothesis of mammalian memory and extend the model to human visual recognition.