Effects of the Novel Acetylcholinesterase InhibitorN-Octyl-1,2,3,4-tetrahydro-9-aminoacridine on Locomotor Activity and Avoidance Learning in Mice

The acetylcholinesterase reversible inhibitorN-octyl-1,2,3,4-tetrahydro-9-aminoacridine (THA-C8) is a new synthesized derivative of tacrine (THA) characterized by an alkyl chain in the molecular structure which ameliorates the penetrability of the compound into the central nervous system. THA-C8 (0.1–5 mg/kg) significantly reduced spontaneous locomotor activity in CD1 mice at a dose of 3 mg/kg. Moreover, THA-C8 (0.2–2 mg/kg) significantly improved shuttle-box avoidance acquisition at doses (0.25, 0.3, 1 mg/kg) not affecting locomotion and that are much lower than the doses reported to be effective for THA in animal models. From the data reported it seems that the new compound could be interesting for therapeutic purposes.     

Examining the relationship between family context and children’s physical activity beliefs: The role of parenting style

Objectives

Previous research studies examining parental influences on children’s physical activity (PA) have focused primarily on parents’ own PA behavior, as well as their PA-related beliefs and socially supportive behaviors. The present study, although aligned with this mainstream parental influence research, was grounded in a broader child development perspective to examine the influence of parenting style on children’s PA beliefs and quality of parent-child communication.

Method

Self-report questionnaires were administered to 173 children ranging in age from 9 to 12 years to assess their perceptions of parenting style, parent-child communication patterns, as well as their own perceptions of fitness competence, value, and goal orientation.

Results

Children’s constellation of beliefs and attitudes regarding PA as well as their perceptions of the parent-child communication process did vary as a function of the type of parenting style they perceived their parents to use. High challenge parenting style was linked to higher perceived fitness competence and value on the part of the children. High support parenting style was linked to more positive perceived parent-child communication patterns.

Conclusion

Parenting style may be a critical underlying family process variable that impacts children’s development of a positive constellation of beliefs about PA. Future work is needed to link parenting style and children’s PA beliefs to their PA behavior.     

Longitudinal Modeling of Adolescents' Activity Involvement, Problem Peer Associations, and Youth Smoking

Longitudinal associations among different types of organized activity involvement, problem peer associations, and cigarette smoking were examined in a sample of 1040 adolescents (mean age = 15.62 at baseline, 16.89 at 15-month assessment, 17.59 at 24 months) enriched for smoking experimentation (83% had tried smoking). A structural equation model tested longitudinal paths between three categories of involvement (team sports, school clubs and activities, and religious activities, measured at baseline and 15 months), problem peer associations (baseline and 15 months), and cigarette smoking behavior (baseline and 24 months). Multi-group analyses indicated pathways differed by type of activity and adolescent gender. Boys' baseline team sports and religious involvement predicted lower levels of smoking at 24 months via continued activity involvement at 15 months. Girls' involvement in school clubs and activities and religious activities indirectly predicted lower levels of smoking at 24 months via reduced exposure to problem peers at 15 months.     

Type of physical exercise and inhibitory function in older adults: An event-related potential study

ObjectivesThe present study was to examine the relationship between exercise type and inhibitory function in older adults using neuroelectric indices.DesignA cross-sectional design was employed in the present study.MethodSixty adults (M = 69.42 years) were categorized into open-skill, closed-skill, and irregular exercise groups according to their history of exercise participation. The participants conducted a flanker task while their behavioral performance and event-related brain potentials were assessed.ResultsThe results indicated that regular exercisers, regardless of exercise type, exhibited a faster reaction time across conditions of the flanker task compared to irregular exercisers. For the P300 amplitude of the open-skill exerciser group, the peak amplitude was larger at the vertex site compared to the frontal site, whereas no site differences were observed in the closed-skill and irregular exerciser groups.ConclusionsThese findings extend current knowledge by suggesting that, for older adults, participation in physical exercise involving increased cognitive demand is associated with better neural efficiency in resource allocation for tasks that require interference control.     

The impact of sport and physical activity on the well-being of combat veterans: A systematic review

ObjectivesThis review examined the potential impact of sport and physical activity upon the subjective and psychological well-being of combat veterans in the aftermath of physical or psychological combat trauma.DesignA systematic review was conducted. The question guiding this review was ‘what is the impact of sport and physical activity on the well-being of combat veterans?’MethodsKey databases were searched for articles relating to the use of sport and/or physical activity in supporting combat veterans. 11 studies were identified as relevant for inclusion. Data from these studies were extracted by means of a directed content analysis, the results of which were reported in a narrative synthesis.ResultsSport and physical activity enhances subjective well-being in veterans through active coping and doing things again, PTSD symptom reduction, positive affective experience, activity in nature/ecotherapy, and quality of life. Impact on psychological well-being includes determination and inner strength, focus on ability and broadening of horizons, identity and self-concept, activity in nature/ecotherapy, sense of achievement/accomplishment, and social well-being. Participating in sport and/or physical activity can also enhance motivation for living.ConclusionsThe review advances knowledge by producing a synthesis of evidence that highlights the value of sport and physical activity for supporting the well-being and rehabilitation of disabled combat veterans and combat veterans diagnosed with Post-Traumatic Stress Disorder. It also develops knowledge by identifying the type of sports and physical activities used to promote well-being, offering the first definition of combat veterans in the sport literature, taking a critical approach, and highlighting the under researched role of nature-based physical activity.     

Relating action to abstract goals increases physical activity reported a week later

ObjectiveThe primary aim of the present study was to investigate whether construing action abstractly versus concretely increases physical activity over a one-week period.Design and methodAn experimental study was conducted in which participants were asked to commit to engaging in physical activity at least four times in the coming week. After making this commitment, participants were assigned randomly to think about the concrete procedures or the abstract purpose of their actions. Additionally, in an attempt to induce differences in level of goal conflict, participants were assigned randomly to receive a reminder of a different or consistent goal. The main outcome variable of interest was the number of minutes spent on physical activity over the following 7-day period.ResultsConsistent with the hypothesis, participants in the abstract condition reported engaging in significantly more minutes of physical activity than did those in the concrete condition. Level of goal conflict did not significantly impact physical activity. The effect of abstract versus concrete thinking on physical activity also was related to the processing of negative affect.ConclusionBy providing evidence that construing action abstractly impacts physical activity, the present investigation makes an important addition to research aiming to identify effective means of increasing physical activity.     

It’s how you say it – The extended Theory of Planned Behaviour explains active transport use in cardiac patients depending on the type of self-report in a hypothesis-generating study

Physical activity (PA) plays an essential part in the secondary prevention of persons with coronary heart disease (CHD). A substantial amount of PA can be gained through increasing the use of active transport modes (walking or cycling for at least 10 min/day) in CHD patients’ daily routine, benefiting the mortality and morbidity rate as well as the environment. The current study aims to investigate the utility of the Theory of Planned Behaviour (TPB) framework extended with habit strength, in understanding the behavioural intention and the behaviour of using active transport modes during the daily travel routine of CHD patients. A cross-sectional survey was conducted from 131 CHD patients. The behaviour was measured using three self-report methods; 1) scale measure, the walking or cycling frequency, 2) direct ATS (Active Travel Score, PA calculated by the directly reported aggregated time spent per day for walking or cycling for travel purposes), and 3) indirect ATS (PA calculated by combining the duration spent on trips by walking and cycling from the self-reported one-day travel diary). Additionally, the participants completed surveys on the direct measures of TPB constructs and habit strength. The results indicated that the TPB constructs explained a 38% variance in the intention to use active transport modes of CHD patients, by which the variance increased to 59% with the addition of habit strength. On the contrary, different behavioural measures were explained differently by TPB and habit strength. The scale measure of behaviour was best predicted (up to 21%) by TPB and habit strength. However, the direct and indirect measures of behaviour were poorly explained (up to 3% and 10% only, respectively). Habit strength moderated the relationship between behaviour (scale measure) and behavioural intention. Surprisingly, higher behavioural intention resulted in a lower behavioural frequency when the habit strength to be active is low. This suggests a limited control over the behaviour thus indicating the intention-behaviour gap. The current study findings highlight the inconsistent predictive utility of TPB across different types of behavioural self-report measures, targeted at the use of active transport modes in CHD patients. However, considering this study as hypothesis-generating, further research is necessary to replicate and extend these findings.     

Repeated exercise class attendance: The role of class members' similarity and social identification

Understanding the malleable factors that underpin people’s ongoing commitment to specific forms of exercise is crucial to facilitate more effective efforts to improve participation rates. To this end, we examined the role of (a) perceiving the members of one’s exercise class to be similar to each other on various dimensions, and (b) possessing a strong social identity as an exercise class member in shaping one’s future participation in that class. During a 3-week intensive sampling period, 779 unique responses were obtained from 278 attendees (who were invited to complete a questionnaire on each occasion they attended an exercise class). On each questionnaire, participants indicated their perceptions of class members’ similarity and their own social identification in relation to the exercise class they had just participated in. Participation was conceptualised as attendance at the same class (i.e., same time and type) the following week and was measured objectively using the fitness facility’s electronic class attendance records. Linear multilevel models showed that participants identified more strongly as members of exercise classes in which they perceived that their fellow attendees were similar to each other: both in general, and in terms of age, physical fitness, and their attitude towards the class. Participants also tended to be more likely to attend a given exercise class the following week to the extent that they reported a strong sense of social identification as a member of that class. These relationships were replicated in a multilevel mediation model, which revealed a significant indirect effect of similarity on class attendance through social identification. Results point to the role that social identification can play in promoting repeated exercise participation and indicate that one way to facilitate exercisers’ greater social identification might be to purposefully create exercise classes and groups comprised of relatively homogenous individuals.     

Associations between parent perceived social cognitive factors and child objectively measured physical activity behaviors among preschool-aged children

Grounded in social cognitive theory (SCT), this study sought to examine whether parents perceived social cognitive factors regarding children's physical activity (PA) behaviors were associated with preschool children's moderate-to-vigorous PA (MVPA) levels. A total of 142 Hong Kong parent-child pairs from five preschools/childcare centers completed all assessments in the cross-sectional study. Children’s (42% girls; mean age = 4.52 ± 0.67 years) PA was measured through accelerometers. Parents (74% mothers; mean age = 37.38 ± 4.63 years) completed a paper-based questionnaire assessing the social cognitive factors on their children’s PA participation. The data were analyzed using latent variable structural equation modeling. Findings revealed that the model showed acceptable fit with the data: χ² (23) = 38.14, p = .025, χ²/df = 1.66, CFI = 0.955, TLI = 0.929, RMSEA = 0.068, 90% CI [0.025, 0.106], and SRMR = 0.072. The model accounted for 39.1% of the variance in the PA behavior of preschool-aged children. Structural equation modelling revealed parental self-efficacy (β = 0.29, 95% CI [0.95, 0.49]) and goal setting (β = 0.25, 95% CI [0.06, 0.44]) were directly associated with children’s MVPA. Outcome expectations (β = 0.09, 95% CI [0.01, 0.03]) and goal setting (β = 0.18, 95% CI [0.05, 0.32]) mediated the association between parental self-efficacy and children’s MVPA. Indirect associations of parental self-efficacy from setting goals via parental support (β = 0.15, 95%CI [0.02, 0.30]) and perceived barriers (β = 0.15, 95% CI [0.05, 0.28]) were uncovered. Results supported the use of SCT in understanding how the parents perceived social cognitive factors predict the PA behaviors of young children. This study provides insight into whether these theoretical variables could be modified or promoted in future intervention programs. Enhancing parents’ abilities to ensure preschool-aged children are physically active is of great importance given the global decline in PA among children.