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31.
The supplementary motor area (SMA) is thought to play in important role in the preparation and organisation of voluntary movement. It has long been known that cortical activity begins to increase up to 2s prior to voluntary self-initiated movement. This increasing premovement activity measured in EEG is known as the Bereitschaftspotential or readiness potential. Modern functional brain imaging methods, using event-related and time-resolved functional MRI techniques, are beginning to reveal the role of the SMA, and in particular the more anterior pre-SMA, in premovement activity associated with the readiness for action. In this paper we review recent studies using event-related time-resolved fMRI methods to examine the time-course of activation changes within the SMA throughout the preparation, readiness and execution of action. These studies suggest that the pre-SMA plays a common role in encoding or representing actions prior to our own voluntary self-initiated movements, during motor imagery, and from the observation of others' actions. We suggest that the pre-SMA generates and encodes motor representations which are then maintained in readiness for action. 相似文献
32.
The neuronal system to process and transfer auditory information to the higher motor areas was investigated using fMRI. Two
different types of internal modulation of auditory pacing (1 Hz) were combined to design a 2×2 condition experiment, and the
activation was compared with that under a visual guidance. The bilateral anterior portion of the BA22 (ant-BA22) and the left
BA41/42 were more extensively activated by the combined modulation condition under the auditory cue than that under the visual
cue. Among the four auditory conditions with or without the two types of internal modulation, the activation in the ant-BA22
was augmented only on the left side by the combined modulation condition. The left ant-BA22 may be especially involved in
integrating the external auditory cue with internal modulation, while the activation on the right side did not depend on the
complexity. The role of the left BA41/42 in motor regulation may be more specific to the processing of an auditory cue than
that on the right side. These two areas in the left temporal lobe may be organized as a subsystem to handle the timing of
complex movements under auditory cues, while the higher motor areas in the frontal lobe support both sensory modalities for
the cue. This architecture may be considered as ‘audio-motor control’, which is similar to the visuo-motor control of the
front-parietal network. 相似文献
33.
34.
Does the right hemisphere take over after damage to Broca's area? the Barlow case of 1877 and its history 总被引:3,自引:0,他引:3
In 1877 Thomas Barlow, a London physician, published a remarkable case of functional recovery of speech following brain damage. It involved a 10-year-old boy who had lost his speech, regained it, and lost it again before he died from a disorder that affected his heart and produced embolisms that subsequently affected other organs, including his brain. Examination of the boy's brain revealed two focal regions of softening; one that affected Broca's area and the left facial-motor area, and another, which occurred weeks later, in the homologous regions of the right hemisphere. Although Barlow was most concerned with motor deficits, others at the turn of the century began to cite this case as strong evidence that the corresponding region of the right hemisphere can take over speech functions for Broca's area on the left. Whether this case really provides good support for functional takeover or vicariation theory is critically evaluated in the light of contemporary research, including PET scan studies involving damage to Broca's speech region. 相似文献
35.
Different types of syntactic information (word category, grammatical gender) are processed at different times during word recognition. However, it is an open issue which brain systems support these processes. In the present event-related fMRI study, subjects performed either a syntactic gender decision task on German nouns (GEN), a word category decision task (WC, nouns vs. prepositions), or a physical baseline task (BASE). Reaction times in WC were faster than in GEN, supporting earlier electrophysiological results. Relative to BASE, both syntactic tasks activated the inferior tip of BA 44. In addition, BA 45 showed activation in GEN, whereas BA 47 was activated in WC. The imaging data indicate that the inferior portion of BA 44 together with type-specific prefrontal areas supports both initial word category related and later syntactic processes. 相似文献
36.
Syntactic working memory and the establishment of filler-gap dependencies: insights from ERPs and fMRI 总被引:9,自引:0,他引:9
In this contribution, we review an ERP experiment and an fMRI experiment which investigated the processing of German wh-questions. On the basis of the ERP results, we will discuss current models of sentence processing and resource distribution during sentence comprehension. We argue that there exists a separate cognitive or neural resource that supports syntactic working memory processes necessary for the temporary maintenance of syntactic information for the parser. In the context of wh-movement, such a memory component is necessary for establishing filler-gap dependencies. The data obtained from the fMRI experiment will be used to discuss the results of previous neuroimaging studies of sentence processing. It is claimed that syntactic working memory, rather than syntactic processing per se, is supported by Broca's Area. 相似文献
37.
本研究将拼嵌技术(chimera technique)和融合技术(Morph tech—nique)结合起来,制作新形式的面孔刺激,将“刺激”和“位置”分离并分别操纵,检验了左右半脸及其位置对面孔吸引力的影响。实验结果显示:(1)“刺激”和“位置”都会影响面孔吸引力;(2)“刺激”的影响是直接的,具体表现为右半脸不论呈现在面孔的左侧还是右侧,其吸引力总是高于左半脸的吸引力;(3)“位置”的影响模式较为复杂,具体表现为左右半脸在原始位置呈现时(右丰脸呈现在右侧,左半脸呈现在左侧),其吸引力总是高于镜像位置。 相似文献
38.
Petitto LA Berens MS Kovelman I Dubins MH Jasinska K Shalinsky M 《Brain and language》2012,121(2):130-143
In a neuroimaging study focusing on young bilinguals, we explored the brains of bilingual and monolingual babies across two age groups (younger 4-6 months, older 10-12 months), using fNIRS in a new event-related design, as babies processed linguistic phonetic (Native English, Non-Native Hindi) and nonlinguistic Tone stimuli. We found that phonetic processing in bilingual and monolingual babies is accomplished with the same language-specific brain areas classically observed in adults, including the left superior temporal gyrus (associated with phonetic processing) and the left inferior frontal cortex (associated with the search and retrieval of information about meanings, and syntactic and phonological patterning), with intriguing developmental timing differences: left superior temporal gyrus activation was observed early and remained stably active over time, while left inferior frontal cortex showed greater increase in neural activation in older babies notably at the precise age when babies’ enter the universal first-word milestone, thus revealing a first-time focalbrain correlate that may mediate a universal behavioral milestone in early human language acquisition. A difference was observed in the older bilingual babies’ resilient neural and behavioral sensitivity to Non-Native phonetic contrasts at a time when monolingual babies can no longer make such discriminations. We advance the “Perceptual Wedge Hypothesis” as one possible explanation for how exposure to greater than one language may alter neural and language processing in ways that we suggest are advantageous to language users. The brains of bilinguals and multilinguals may provide the most powerful window into the full neural “extent and variability” that our human species’ language processing brain areas could potentially achieve. 相似文献
39.
Tschirren M Laganaro M Michel P Martory MD Di Pietro M Abutalebi J Annoni JM 《Brain and language》2011,119(3):238-242
Purpose
Bilingual aphasia generally affects both languages. However, the age of acquisition of the second language (L2) seems to play a role in the anatomo-functional correlation of the syntactical/grammatical processes, thus potentially influencing the L2 syntactic impairment following a stroke. The present study aims to analyze the influence of late age of acquisition of the L2 on syntactic impairment in bilingual aphasic patients.Methods
Twelve late bilingual participants (speaking French as L2 and either English, German, Italian or Spanish as L1) with stroke-induced aphasia participated in the study. The MAST or BAT aphasia batteries were used to evaluate overall aphasia score. An auditory syntactic judgement task was developed and used to test participants syntactic performance.Results
The overall aphasia scores did not differ between L1 and L2. In a multiple case analysis, only one patient had lower scores in L2. However, four patients presented significantly lower performances in syntactic processing in the late L2 than in their native language (L1). In these four patients the infarct was localized, either exclusively or at least partially, in the pre-rolandic region.Conclusion
This pilot study suggests that, in late bilingual aphasics, syntactic judgment abilities may be more severely impaired in L2, and that this syntactic deficit is most likely to occur following anterior lesions. 相似文献40.
This study investigated how target sex, target age, and expressive ambiguity influence emotion perception. Undergraduate participants (N = 192) watched morphed video clips of eight child and eight adult facial expressions shifting from neutral to either sadness or anger. Participants were asked to stop the video clip when they first saw an emotion appear (perceptual sensitivity) and were asked to identify the emotion that they saw (accuracy). Results indicate that female participants identified sad expressions sooner in female targets than in male targets. Participants were also more accurate identifying angry facial expressions by male children than by female children. Findings are discussed in terms of the effects of ambiguity, gender, and age on the perception of emotional expressions. 相似文献