Septal damage in infant and adult rats: Effects on activity,emotionality, and muricide

Septal lesions produced signs of increased emotionality in the adult rat, the septal syndrome (hyperresponsiveness to handling; in the open field: decreased rearing and ambulation activity, increased defecation, deficient habituation) being more or less complete and more or less marked depending on the age at which the lesion was performed (7 days or 3 months), the extent of the lesion (restricted to the septum or extending to more ventrally located structures) and the environmental conditions in which the animals were reared (in groups or in isolation). All septal lesions provoked a similar and significant increase in the probability of occurrence of mouse-killing behavior, irrespective of age of operation, extent of lesion and kind of rearing environment. In a 24-hour actography starting at 11:30 a.m., the rats septalectomized at adult age were less active than controls during the initial period, while all septals were markedly more active than controls during the night period. Early septal lesions only transiently disrupted weight gain. The results obtained point to complex interactions between the effects of early brain damage and environmental conditions.     

论政治道德的定位

政治生活的整合和政治文明的建设要求对政治道德进行合理的定位。政治道德的定位问题既涉及政治道德体系的内容问题,又关涉什么样的政治道德才是合理的问题。政治道德应该定位于政治公共领域这一客观基础;应该定位于个人权利与公共利益相结合的视角;应该定位于目的（或者功利）与道义（或者义务）的统一。     

关于高中生认知方式的测验研究

对２５４名高中生,５７名大学生和６８名初中生（已去掉不合格者）进行了“镶嵌图形测验”,探讨了当前我国高中生认知方式场依存性－独立性发展的特点。研究结果表明：（１）在高中阶段,学生认知方式的场依存性－独立性的发展有其相对稳定性。（２）高中男女生的认知方式发展存在明显的性别差异。（３）文理分班对高中生认知方式的发展并无明显影响。（４）高中生的场依存性─独立性认知方式与其语文、数学学习成绩相关不明显。     

Thawing the 'frozen accidents': the archetypal view in countertransference

Jung's concepts of psyche and psychic energy are relevant in countertransference. Working with Jung's archetypes as 'transconscious' dynamic fields of probabilities helps the analyst, as a clinician and teacher with limited human consciousness, to confront and recognize the unconscious cross-purposes of 'anomalous' countertransference, and to convert it to insightful 'participatory' countertransference-Jung's archetypes will be juxtaposed with William James's fields, Gerald Edelman's qualia, and most particularly with Murray Gell-Mann's 'frozen accidents'. Two vignettes – from A clinical and a training setting – suggest chat from a Jungian perspective, countertransference may be seen at the psychic juncture where ego, the personal shadow, the interpersonal other and the archerype of the collective unconscious meet in the determining images of a life, fantasy, dream, analysis, and seminar. So-called 'parallel process' will be seen as enclosure in the circles of reference emanating from the patient's experiences in those arenas deemed archetypal, i.e., structurally significant. The relativity of unconscious time will be mentioned. Jung's notion that, called or uncalled, the archetypes are present, informs the thesis that we must name archetypal images if we are to know them, and we must know them to be free.     

A qualitative aspect of learning-sensitive open field ambulation in mice

Maze training was shown to affect qualitative aspects of the learning-sensitive open-field (OF) ambulation in male Swiss albino mice. The changes in thigmotactic (wall-seeking) behaviour were most pronounced when significant signs of learning occurred, usually on the third day of training. Also daily changes in thigmotaxis from before to after training were found. Mice not subjected to maze training exhibited a different thigmotactic pattern of behaviour. The present series of experiments indicated that separate starting-points (centre or wall) influenced the thigmotactic behaviour as opposed to the shape of the OF (circular or square).     

Sex differences in functional cerebral asymmetries in a repeated measures design

The aim of the present study was to analyze whether task repetitions which are an inevitable part of repeated measures designs might induce performance alterations specific for gender and hemisphere. Male and female subjects conducted twice a lexical decision, a polygon recognition, and a face discrimination task as a visual half field paradigm with the two experimental sessions repeated by 2 weeks. The results show that only in female subjects can a session effect for the lexical decision and the polygon recognition task be demonstrated which is hemisphere specific. Thus, repeated measures designs seem to have a gender- and hemisphere-specific effects of their own which could confound with other variables under study.     

Open Field Motor Patterns and Object Marking, but Not Object Sniffing, Are Altered by Ibotenate Lesions of the Hippocampus

Objectmarking and object sniffing were assessed in an open field during six 5-min trials in unoperated Long-Evans rats and rats with ibotenate lesions of the hippocampus and/or neocortex. Object marking was higher in hippocampally lesioned rats than in unoperated rats. Object marking did not differ between neocortically lesioned rats and unoperated rats. Object sniffing durations and visits did not differ between unoperated and hippocampally lesioned rats nor between unoperated and neocortically lesioned rats. A new object elicited longer sniffing by both unoperated and hippocampally lesioned rats. Neocortically lesioned rats did not show this effect. There were no effects of the new object on marking. Computerized tracing of open field paths revealed a smaller perimeter track for hippocampally lesioned rats than for unoperated rats. This difference reflected distinct ambulatory patterns. Hippocampally lesioned rats made stereotyped hind-limb pivots at each corner, while normal rats used forelimb pivots or reared and reoriented adjacent to the wall. Rearing was lower in hippocampally lesioned rats, and higher in neocortically lesioned rats, than in unoperated rats. These data indicate that investigative object behavior (sniffing) is resistant to the effects of hippocampal damage, while object-elicited marking and motoric output may be profoundly altered. The data on sniffing suggest either that (1) the noticeability of the objects used elicited investigative behaviors in hippocampally damaged rats comparable to those of novelty-induced exploration in normal rats or (2) object exploration is not used to create a spatial map, and, hence, not disturbed by hippocampal loss. Object marking may require spatial locale information to be exercised normally, or may index the mediation of an olfactory-modulated behavioral pattern through the hippocampal system.     

Ethics of field research: Do journals set the standard?

To determine whether ethical issues concerned with field research are addressed in the peer-review process, instructions to authors and reviewers of 141 (mainly natural science) journals were examined to ascertain how often ethical issues were mentioned. Only one-third (n=41) of responding journals addressed ethical issues in their instructions to authors or reviewers. When ethical issues were considered, most of the journals limited their concerns to ethical issues associated with animal and general human experimentation. No journal mentioned ethical practices in working with indigenous peoples or on traditional lands. Only two journals addressed the ethics of research in sensitive areas in their instructions to authors, only one in its instructions to reviewers. We suggest that peer-reviewed journals respond to an emerging issue in ecological research by formally incorporating research ethics into their instructions to authors and reviewers. Furthermore, these instructions should address the ethical issues associated with field research and in working with indigenous peoples and on traditional lands.     

Gender differences in acute and chronic stress in Wistar Kyoto (WKY) rats

While females are considered more susceptible to depressive behavior, this assertion is not strongly supported by the experimental literature. Since stress contributes to depressive behavior, male and female Wistar Kyoto (WKY) rats were exposed to either one session (acute stress) or 5 sessions (chronic stress) of restraint plus cold in order to study depressive behavior in male and female rats. After their respective treatment exposure, rats were tested in the open field test (OFT) and for retention of a passive-avoidance (P-A) task. One stress session resulted in significant immobility in the OFT for males, whereas 5 sessions were required to produce similar immobility in female rats. Acute stress interfered with the retention of the P-A response for males, while both acute and chronic stress produced poor P-A responses in female rats. Food consumption decresed, progressively, as a function of stress sessions, in female rats, whereas feeding in males returned to control levels after five stress days. Both acute and chronic stress exacerbated the stress ulcer response in male rats, but not in female rats. Chronic, but not acute, stress resulted in an increase in serotonin transporter mRNA levels in the dorsal raphe nucleus of both male and, female rats. The general consensus from these data suggested that female rats were more vulnerable to chronic stress and consequently supported the notion that females may be more susceptible to stress induced behavioral depression.     

THE DOCTRINE OF CREATION AND MODERN SCIENCE

Abstract. In contrast to Christian theology that has ignored science, this essay suggests that a credible doctrine of God as creator must take into account scientific understandings of the world. The introduction of the principle of inertia into seventeenth-century science and philosophy helped change the traditional idea of God as creator (which included divine conservation and governance) into a deist concept of God. To recapture the idea that God continually creates, it is important to affirm the contingency of the world as a whole and of all events in the world. Reflecting on the interrelationship of contingency and natural law provides a framework for relating scientific theories of a universal field, the concept of emergent evolution, and the theological concept of eternal divine spirit active in all creation.