“自杀”：一个重要的伦理问题

自杀现已成为人类死亡十大原因之一 ,而且呈现出低龄化的趋势 ,越来越引起社会的关注。因而 ,从政治、经济、社会、疾病、文化等多视角来寻找自杀的外部原因 ,对探究这个重要的伦理问题是有益的。     

The factor structure of the Eysenck Personality Profiler in Russia

One hundred and seventy seven males and 399 females completed a translated short version of the Eysenck Personality Profiler (EPP-S). Two hundred and ninety four Ss also completed the EPQ. By means of item analysis, further shortening of the EPP was achieved, while retaining adequate psychometric characteristics and convergent validity with EPQ scales. Confirmatory factor analysis (CFA) confirmed the Eysenck hierarchical model of personality with three basic dimensions and showed stability of the EPP factor structure across genders and sub-samples of different origin. However, CFA showed that only E and P were independent, while N was correlated with E and P.     

Structural Validation of the Hamilton Depression Rating Scale

Despite the prolific use of the Hamilton Depression Rating Scale (HDRS), there have been no prior studies using confirmatory factor analysis (CFA) to compare competing HDRS latent structures. The current study undertakes this task, examining CFAs on 397 older adults on the most stable latent models previously posited and a new rationally derived model by Cole and Motivala. CFAs were evaluated in their original first-order structure and in hierarchically related counterparts. All hierarchical models performed significantly better than their first-order counterparts. Moreover, the hierarchical Cole and Motivala model was significantly better on all comparative criteria than any of the other models. However, none of the tested models obtained sufficient fit with the data suggesting psychometric, scoring, or content limitations of the scale.     

复发转移性乳腺癌患者血浆VEGF水平的临床价值研究

探讨血浆血管内皮生长因子（P-VEGF）在乳腺癌术后复发转移患者中的表达情况及临床意义。采用酶联免疫吸附试验检测50例术后复发转移性乳腺癌患者及20例乳腺良性疾病对照组的P-VEGF含量,同期采用微粒子化学发光法检测术后复发转移性乳腺癌患者血清CEA和CA15-3的表达情况,进行对比研究。结论认为转移肿瘤细胞可产生大量...     

大学生学校适应性简明问卷的编制与验证

该研究旨在探讨当前大学生学校适应性的结构维度并编制简明评定问卷,运用了探索性因素分析和验证性因素分析的方法。结果表明,我国大学生学校适应性的结构维度包括四个方面的内容,分别是学习能力适应、人际关系适应、学校政治适应、学校文化适应。研究结果还显示,大学生学校适应性评定问卷具有良好的信度和效度指标,问卷的α系数达到0.80,探索性因素分析中总方差解释量达到62.89%,验证性因素分析的各项指标均达到理想水平。     

青少年情绪调节策略的结构与测量

情绪调节策略是个体应对消极情绪的重要手段,对个体身心发展起着重要的作用。通过采用文献综述和实证分析相结合的方法编制符合我国青少年实际的情绪调节策略量表。量表包括认知重评、积极设想、求助他人、行为转移、自我责备、沉思默想、自我压抑、发泄不满和攻击他人九个维度。对量表进行信效度检验的结果表明,该量表具有良好的信度效度指标。     

高校毕业生择业焦虑问卷的跨地区验证和比较

对高校毕业生择业焦虑问卷的结构进行必要的修订和跨地区验证。使用修订后的问卷对内蒙古、陕西、山东、广东等四省区7所大学的1458名2007届毕业生进行调查,考察不同地区毕业生择业焦虑状况。结果表明:修订后的问卷具有较好的心理测量学指标和跨地区普遍适用性;不同地区高校毕业生的择业焦虑在4个维度和问卷总分上均存在显著差异。说明问卷的修订是有效的,可用于不同地区毕业生择业焦虑的测量和心理教育效果的评定;地区间的经济、文化、教育水平的差距可能是导致毕业生择业焦虑差异的主要因素。     

The Factor Structure of the Frost Multidimensional Perfectionism Scale in University Students

The Frost Multidimensional Perfectionism Scale (FMPS) is a widely used measure of perfectionism. Previous studies of the nature of the factors of the FMPS have resulted in mixed findings and have failed to identify a stable factor structure. This study investigated the factor structure of the FMPS using both exploratory and confirmatory factor analysis (CFA), addressing previous methodological limitations. Participants were 6,449 students from two Australian universities. Exploratory factor analysis suggested a five‐factor model and a reduction in variables from 35 to 29 (FMPS‐29). CFA demonstrated goodness of fit of the revised measure. We also compared our model with a number of existing measurement models of perfection and found the proposed model provided a superior fit for this university student population. Support was found for the two second‐order constructs commonly referred to as adaptive and maladaptive perfectionism, although there appears to be little benefit in using this model over the first‐order model. Implications of the findings are discussed.     

早期剥夺所致大鼠抑郁样行为与海马BDNF mRNA表达变化

为探讨早期剥夺对大鼠行为与海马脑源性神经营养因子(BDNF)mRNA表达的影响,将新生的SD大鼠随机分为正常对照组与早期剥夺组,早期剥夺组在出生后1～14d每天孤养4h。监测体重,在出生后36?64天进行液体消耗试验,每周一次。12w龄时,进行穿梭箱试验,酶联免疫法检测海马BDNF含量,原位杂交法观察海马BDNF mRNA的表达。早期剥夺组大鼠体重显著低于正常对照组(p0.01),糖水摄入量与糖水偏爱显著低于正常对照组(p0.05或p0.01)。穿梭箱试验中,早期剥夺组大鼠在训练时的穿梭反应次数显著少于正常对照组(p0.05),在测试时,两组大鼠的被动逃避行为、主动逃避行为与逃避错误次数无显著差异。早期剥夺组大鼠海马BDNF含量、CA1区和CA3区BDNF mRNA表达显著低于正常对照组(p=0.05或p0.05)。提示早期剥夺可导致大鼠生长减慢,表现出快感缺失的抑郁样行为,但未诱导成年大鼠表现出明显的习得性无助倾向,早期剥夺能下调成年大鼠海马BDNFmRNA的表达。     

从EDRF的发现来看科学研究中的偶然性和必然性

本文通过讲述血管内皮舒张因子(endothelium-derived relaxing factor,EDRF)发现过程中的一些事例,讨论科学研究中的偶然性与必然性之间的辩证关系。把握偶然性和必然性之间的对立统一关系,有助于深化对自然和社会规律的认识。科研工作者应运用辩证唯物主义的观点,重视偶然现象,探索必然规律。