No blank slates: Pre-existing schemas about pharmaceuticals predict memory for side effects

Objectives: Attribution of symptoms as medication side effects is informed by pre-existing beliefs about medicines and perceptions of personal sensitivity to their effects (pharmaceutical schemas). We tested whether (1) pharmaceutical schemas were associated with memory (recall/recognition) for side effect information (2) memory explained the attribution of a common unrelated symptom as a side effect.

Design: In this analogue study participants saw the patient leaflet of a fictitious asthma drug listing eight side effects.

Main outcome measures: We measured recall and recognition memory for side effects and used a vignette to test whether participants attributed an unlisted common symptom (headache) as a side effect.

Results: Participants who perceived pharmaceuticals as more harmful in general recalled fewer side effects correctly (r_{Correct Recall} = ?.273), were less able to differentiate between listed and unlisted side effects (r_{Recognition Sensitivity} = ?.256) and were more likely to attribute the unlisted headache symptom as a side effect (r_{side effect attribution} = .381, ps < .01). The effect of harm beliefs on side effect attribution was partially mediated by correct recall of side effects.

Conclusion: Pharmaceutical schemas are associated with memory for side effect information. Memory may explain part of the association between pharmaceutical schemas and the attribution of unrelated symptoms as side effects.     

A tale of two processes: On Joseph Henrich’s the secret of our success: How culture is driving human evolution,domesticating our species,and making us smarter

We situate Henrich’s book in the larger research tradition of which it is a part and show how he presents a wide array of recent psychological, physiological, and neurological data as supporting the view that two related but distinct processes have shaped human nature and made us unique: cumulative cultural evolution and culture-driven genetic evolution. We briefly sketch out several ways philosophers might fruitfully engage with this view and note some implications it may have for current philosophic debates in moral and political theory and over the nature of extended cognition. We end by noting how Henrich’s view of the source of cultural design and innovation, and the prominence of place he gives to the extended process of cultural evolution, cuts against a cluster of broad but common views about human minds, recasting putative bugs as features and indicating that many of the distinctive features of our individual minds evolved to allow them to be effective cogs in the larger, more productive cultural machine.     

Is it possible to experimentally determine the extension of cognition?

Various analytical tools originally developed for theories of mechanistic explanation have recently been imported into the ongoing debate on the hypothesis of (extracerebrally) extended cognition (HEC). One such tool that appears particularly relevant to that debate is Craver’s mutual manipulability account of constitution (MM), most of all because it promises to settle the debate on experimental grounds. This paper investigates whether it is possible to deliver on that promise. We first find that, far from grounding an experimental evaluation of HEC, MM is conceptually incompatible with both internalist and externalist accounts of cognition. Next, we propose a suitable modification of MM, MM*, but it turns out that MM* presupposes rather than produces clarity on the extension of cognition. Moreover, subject to MM* the inference to constitution is radically empirically underdetermined. Finally, we argue that our results can be generalized and conclude that, for principled reasons, it is impossible to experimentally determine whether cognitive processes have extracerebral constituents. Determining the extension of cognition is an inherently pragmatic matter.     

Accessibility and characteristics of memories of the future

Recent research suggests that some imagined future events are encoded in memory, leading to the formation of “memories of the future”. However, questions remain regarding the exact components of future event simulations that are encoded and the factors that determine their accessibility. To address these questions, the present study investigated memory for previously imagined future events using both free and cued recall tasks. The results showed that most future event simulations were successfully encoded and remained available in memory after a one week delay, but only some of them were readily accessible, whereas others could only be accessed when relevant cues were provided. Persons and locations were particularly well remembered, suggesting that these components are central to the simulation and memorisation of future events. We also found that memory for future event simulations was related to the clarity and familiarity of represented persons, the subjective feelings of pre-experience and mental time travel, the importance of imagined events to personal goals, and their emotional intensity during the initial simulation phase. Taken together, these findings expand our understanding of the formation, accessibility, and characteristics of memories of the future.     

心理分离研究进展*

心理分离指的是个体在非工作时间里从工作中分离出来,个体不仅身体上远离工作场所,精神上也摆脱掉工作的事情,对员工工作压力的恢复过程非常关键。首先,文本概述了心理分离的概念及其进展;其次,论述了心理分离研究现状;最后,阐述了心理分离的已有研究存在的问题和未来研究的方向。     

糖尿病性视网膜病变的个体化治疗

糖尿病性视网膜病变(DRP)是糖尿病患者致盲的一个主要原因。其发病的多样性决定了对其治疗应该个体化。就其个体化治疗的依据、方法的研究及具体的措施运用哲学原理加以综述。     

Lifestyle traits as predictors of driving behaviour in urban areas of Greece

The aim of this study was to examine possible links between different lifestyle patterns and aberrant driver’s behaviour. Personal interviews were conducted in a representative sample of 324 adults (18–65), all residents of Crete. Aberrant driver’s behaviour was assessed by the ‘driver behaviour questionnaire’ (DBQ). Also to measure different dimensions of lifestyle, first, a 26-items questionnaire was used, and second, three questions measuring ‘driving without destination’, related in previous findings with road accident risk. Four lifestyle patterns: ‘religion/tradition’, ‘driving aimlessly’, ‘sports’ and ‘culture’ are significant predictors of ordinary violations. ‘Driving without destination’ has a significant effect all three DBQ factors (b positive). ‘Religion/tradition’ was related only to ordinary violations (b negative) and ‘sports’ has a positive impact on ordinary violations and a negative impact on ‘errors’. Two lifestyle factors are related to more dangerous driving: ‘Driving without destination’ and/or pursuing a more ‘athletic way of living’. Road safety campaigns must teach the first group to use other hobbies and activities to vent their feelings and the second, not to overestimate their abilities, while driving.     

The spiritual well-being questionnaire: Testing for model applicability, measurement and structural equivalencies, and latent mean differences across gender

Fisher (1998) proposed a spiritual well-being model, comprising primary factors for the domains of personal, communal, environmental and transcendental well-being, that cohere to form a single higher order or global spiritual well-being dimension. In line with this model, Gomez and Fisher (2003) published the Spiritual Well-Being Questionnaire (SWBQ), with scales for measuring personal, communal, environmental and transcendental spiritual well-being. This study used multi-group confirmatory factor analysis (CFA) to examine gender equivalencies of the measurement and structural models of the SWBQ, and the latent mean in the four SWBQ factors. A total of 3101 females and 1361 males, with age ranging from 15 to 32 years, completed the SWBQ. The statistical fit results supported the invariance of the measurement model, and some aspects of the structural model. The practical fit indices results provided support for the invariance of both the measurement and structural models. The results also showed little gender differences. Together, these findings support gender equivalencies for the SWBQ.     

The influence of perceived prison crowding on male inmates' perception of aggressive events

This study examines whether, in a male prison, the subjective experience of crowding increases the likelihood that events are perceived as aggressive in nature, and whether the protagonists involved are viewed as more hostile, malevolent, and aggressive. In addition, this paper also examines the possible mediating effects of stress, arousal, and psychological well‐being on two hypothesised relationships. First, these mediating factors are examined for the link between individuals' personal space preferences and their perceived level of crowding. Second, these factors are examined for the link between perceived crowding and interpretations of an aggressive event. Such associations may help to explain why crowding and aggression are linked within a social interactionist perspective. The results confirmed previous findings that crowding is linked to increases in arousal and stress, and a reduction in psychological well‐being. This study also found, however, that those inmates who experienced crowding were also more likely to interpret behaviour as aggressive and violent. This relationship was not mediated by arousal, stress, or psychological well‐being. However, these factors were found to partially operate in the relationship between personal space preferences and the experience of subjective crowding. The implications of this study for social interactionist explanations of the link between crowding and prison violence are offered. Aggr. Behav. 30:273–283, 2004. © 2004 Wiley‐Liss, Inc.     

新的人身损害赔偿司法解释对医疗行业的影响及医疗行业的对策

新的人身损害赔偿司法解释将于2004年5月1日正式施行.预计将引起医疗纠纷诉讼大量增加,且多以医疗侵权为诉因,医疗机构的赔偿费用也会大幅上升.医疗行业应从减少医疗过失,改善医患关系,完善医疗事故鉴定等方面加以应对.