对医学基础研究中“确凿证据”的认识

医学基础研究中得到的确切可靠、无可辩驳的结论,可称为“确凿证据”。其重要性在于能对“一般证据”做出判断;可据此设计实验,提出并验证假说。所以准确判断十分重要,判断错误将误导实验,延缓实验进程。可分为两类：直接可见的结果或是经过严密实验设计得出的结论。我们要慎重判断“确凿证据”,也要善于利用其得出结论。     

REINFORCER ACCUMULATION IN A TOKEN-REINFORCEMENT CONTEXT WITH PIGEONS

Four pigeons were exposed to a token-reinforcement procedure with stimulus lights serving as tokens. Responses on one key (the token-production key) produced tokens that could be exchanged for food during an exchange period. Exchange periods could be produced by satisfying a ratio requirement on a second key (the exchange-production key). The exchange-production key was available any time after one token had been produced, permitting up to 12 tokens to accumulate prior to exchange. Token accumulation, measured in terms of both frequency (percent cycles with accumulation) and magnitude (mean number of tokens accumulated), decreased as the token-production ratio increased from 1 to 10 across conditions (with exchange-production ratio held constant), and increased as the exchange-production ratio increased from 1 to 250 across conditions (with token-production ratio held constant). When tokens were removed, accumulation decreased markedly compared to conditions with tokens and the same schedules. These data show that token accumulation is an orderly function of token-production and exchange-production schedules, and they are broadly consistent with a unit-price model based on local and global responses per reinforcer.     

The effectiveness of UK student counselling services: an analysis using the CORE System

Despite concern surrounding the mental health of students, brought about by the government's policy of widening participation and increasing demands upon students, the effectiveness of student counselling has been a neglected research area. This study examines data from seven UK student counselling services using the CORE System in the routine evaluation of their services. Results indicate that counselling is effective, with 70% (service range 67% to 83%) of clients with outcome measures available showing reliable improvement on the CORE-OM from pre- to post-therapy. However, students who complete a course of counselling show significantly greater improvement, according to practitioner pre- and post-therapy severity ratings of depression and anxiety, than those clients who drop out or have an unplanned therapy ending (effect size 1.03, 0.85, respectively). The stage at which students drop out of therapy is important, with those students dropping out of therapy before the third session being the most vulnerable. The implications of these findings are discussed.     

The Effect of Knowledge Accumulation on Support for Workplace Accommodation

We investigated the relationship between knowledge about the demonstrated benefits of breastfeeding and individual support for breastfeeding accommodation in the workplace. We tested our hypotheses by asking participants to respond to vignettes that described the factors a Director of Human Resources had to consider in responding to the needs of a breastfeeding employee. We found that participants had a low level of knowledge about the benefits of breastfeeding for child, mother, and organization. Participants with children reported stronger support for accommodation, and the level of knowledge about the benefits of breastfeeding mediated this effect. The results showed that participants in executive level positions, and who had no children, were the least supportive of accommodation. There were no occupational differences in responses to the support measure.     

Evaluating Corroborative Evidence

How should we evaluate an argument in which two witnesses independently testify to some claim? In fact what would happen is that the testimony of the second witness would be taken to corroborate that of the first to some extent, thereby boosting up the plausibility of the first argument from testimony. But does that commit the fallacy of double counting, because the second testimony is already taken as independent evidence supporting the claim? Perhaps the corroboration effect should be considered illogical, since each premise should be seen as representing a separate reason in a convergent argument for accepting the claim as plausible. In this paper, we tackle the problem using argumentation schemes and argument diagramming. We examine a number of examples, and come up with two hypotheses that offer methods of analyzing and evaluating this kind of evidence.     

The silent voices of research: What can we do to help them speak?1

The authors challenge the legitimacy of making commissioning decisions based solely upon the current outcome research for the psychological treatments. They argue that this outcome data does not represent the treatment needs of the patient who fails to complete a therapy. They call for a shift in the focus of research in order to right this oversight.     

话题结构对语篇情绪累加的影响

在阅读理解的过程中,读者能够自动对语篇中的情绪进行推断。本研究采用自定步速阅读的方法,分别在外显和内隐两种情绪加工的任务下,考察话题结构对语篇情绪累加的影响。结果发现,在实验一的外显情绪判断任务下,话题结构未显示出对语篇情绪累加的明显作用;在实验二的内隐情绪理解任务下,当话题延续时,读者对有两个情绪线索的语篇的阅读时间短于仅有一个情绪线索的语篇,此时情绪的累加促进了当前句的加工,而话题转换时,二者没有显著差异,说明此时读者在新结构下建立当前句的情绪表征,并不在先前情绪的基础上进行累加。     

The role of temporal intervals on reinforcer accumulation

Animals accumulate reinforcers when they forgo the opportunity to consume available food in favor of acquiring additional food for later consumption. Laboratory research has shown that reinforcer accumulation is facilitated when an interval (either spatial or temporal) separates earning from consuming reinforcers. However, there has been no systematic investigation on the interval separating consuming reinforcers from earning additional reinforcers. This oversight is problematic because this second interval is an integral part of much of the previous research on reinforcer accumulation. The purpose of the current study was to determine the independent contributions of these two temporal intervals on reinforcer accumulation in rats. Each left lever press earned a single food pellet; delivery of the accumulated pellet(s) occurred upon a right lever press. Conditions varied based on the presence of either an intertrial interval (ITI) that separated pellet delivery from the further opportunity to accumulate more pellets, or a delay‐to‐reinforcement that separated the right lever press from the delivery of the accumulated pellet(s). Delay and ITI values of 0, 5, 10 and 20 s were investigated. The delay‐to‐reinforcement conditions produced greater accumulation relative to the ITI conditions, despite accumulation increasing the density of reinforcement more substantially in the ITI conditions. This finding suggests that the temporal separation between reinforcer accumulation and subsequent delivery and consumption was a more critical variable in controlling reinforcer accumulation.     

Second-Order Science and Policy

In March 2016, an interdisciplinary group met for two days and two evenings to explore the implications for policy making of second-order science. The event was sponsored by SITRA, the Finnish Parliament's Innovation Fund. Their interest arose from their concern that the well-established ways, including evidence-based approaches, of policy and decision making used in government were increasingly falling short of the complexity, uncertainty, and urgency of needed decision making. There was no assumption that second-order science or second-order cybernetics would reveal any practical possibilities at this early stage of enquiry. On the other hand, some members of the group are practioners in both policy and in facilitating change in sectors of society. Thus, the intellectual concepts were strongly grounded in experience. This is an account of the deliberations of that group and some reflections on what came out of the various shared contributions and ensuing dialogues. The overall conclusion of the event is that there definitely are possibilities that are worthy of further research and exploration.