Minimal experience required for immediate-early gene induction in zebra finch neostriatum

We show that a single presentation of a zebra finch song, 2 s in duration, will induce an "immediate-early gene" response in the caudomedial neostriatum of zebra finches (Poephila guttata). Repetition of this stimulus 10 times is sufficient to induce a maximal increase in RNA and protein, detected 30 and 90 min later respectively. Thus very brief stimuli can set in motion a slow genomic process in the brain which takes hours to resolve. Immediate-early gene function is often considered in the context of a "feedback" model (i.e., to consolidate memories of the inducing event). However, based on the long lag observed here between initiation and full expression of the molecular response, we suggest an alternative, ethologically based, "feed-forward" model in which exposure to a novel or significant context triggers an increase in the efficiency of memory capture processes for subsequent experiences.     

Fibromyalgia impact and depressive symptoms: Can perceiving a silver lining make a difference?

Individuals with fibromyalgia are at greater risk for depressive symptoms than the general population, and this may be partially attributable to physical symptoms that impair day-to-day functioning. However, individual-level protective characteristics may buffer risk for psychopathology. For instance, the ability to perceive a “silver lining” in one’s illness may be related to better mental and physical health. We examined perceived silver lining as a potential moderator of the relation between fibromyalgia impact and depressive symptoms. Our sample of persons with fibromyalgia (N = 401) completed self-report measures including the Fibromyalgia Impact Questionnaire-Revised, Depression Anxiety Stress Scales, and the Silver Lining Questionnaire. Moderation analyses covaried age, sex, and ethnicity. Supporting hypotheses, increasing impact of disease was related to greater depressive symptoms, and perceptions of a silver lining attenuated that association. Despite the linkage between impairment and depressive symptoms, identifying positive aspects or outcomes of illness may reduce risk for psychopathology. Therapeutically promoting perception of a silver lining, perhaps via signature strengths exercises or a blessings journal, and encouraging cognitive reframing of the illness experience, perhaps via Motivational Interviewing or Cognitive Behavioral Therapy, may reduce depressive symptoms in persons with fibromyalgia.     

A dyadic personality perspective on the Michelangelo phenomenon: How personality traits relate to people’s ideal selves and their personal growth in romantic relationships

Personality matters for romantic relationships. In this study, we investigated personal growth in couples (the Michelangelo phenomenon) and targeted questions of personality effects. We explored whether traits intrapersonally predict ideal selves as well as whether traits intra- and interpersonally account for why some people are more likely to benefit from the Michelangelo phenomenon than others. We used data from a 4-year study of 163 couples (M_age = 50.72 years). Logistic regressions indicate complementarity effects for men, in that those high in neuroticism were likely to wish to be emotionally stable. Actor–partner interdependence models revealed positive actor effects of emotional stability, extraversion, and agreeableness, while few partner effects emerged. We discuss dyadic personal growth in view of individual trait differences.     

论保护基因隐私需要引入权利形式

基因技术的发展将基因隐私保护问题摆在人类面前,“采用怎样的方式才能有效保护基因隐私”是一个亟待解决的疑问。从分析侵犯基因隐私所带来的社会危害出发,对“权利形式是否适用于保护基因隐私”这一问题进行分析,并得出肯定性结论。