Rythmicités de l’attention des enfants et synchronisation,perspective socioécologique

This study investigates the impact of socioecological synchronization on the level and variations in children's attention at school. The aim was to re-examine previous results and broaden the chronopsychological scope of the research to include new synchronizers originating from proximal ecological niches. Two time-management factors were considered, the organization of the school timetable and the regular and predictable daily time with parents, influenced by work organization and compromises within the family. Two studies were conducted on a total of 498 children between six and 11 years of age. Results confirm a daily attention pattern. The level of performance and the daily pattern are affected by the two time-management factors whose beneficial or adverse influence depends on the child's age. Thus, while the weekly school timetable organized over four days has the strongest negative impact on attention performance for the two age groups, desynchronization due to a longer week-end is greater in the older children. The effects of the two possible four-and-a-half-day timetables also differ according to age. The benefits of working on Wednesdays for younger children appeared less beneficial for the older pupils. Regular and predictable daily time with parents does appear to play a role which also varies according to age, as it has an effect on younger children but has no impact on older children's attention or performance. This study confirms the synchronizing role of temporal messages from school and parental niches in the level and variations in children's attention at school, and is in line with the ecological point of view demonstrated by chronobiological studies. These findings support the importance of research that takes an overall approach to the child's environment. Further work should investigate the prioritization of social synchronizers according to their proximity to the child and how they interact.     

Apprendre à résoudre des problèmes en favorisant la construction d’une représentation alternative chez des élèves scolarisés en éducation prioritaire

In arithmetic problems solving, the representation of the problem spontaneously induced by the content of the statement is not always compatible with the solving strategy. This study evaluates a learning approach designed to lead pupils to build an alternative representation to the one spontaneously induced. In this paper, we evaluate the efficiency of this learning approach with children with learning difficulties enrolled in a priority education network. This learning by semantic recoding is a process based on an analogy between the problems and a comparison of strategies. The results show that after learning, the pupils built alternative representations.     

When to cooperate and when to compete: Emotional intelligence in interpersonal decision-making

This study examined the relationship between emotional intelligence (EI), assessed with an ability test, and interpersonal decision-making using the Prisoner’s Dilemma Game (PDG). Previous research found that individuals who self-report high EI tend to cooperate more than others in the Prisoner’s Dilemma. We relativize these findings by showing that individuals scoring high on an ability measure of EI choose effective strategies to deal with three different PDG conditions during real interactions. This suggests that emotionally intelligent individuals are not rigidly predisposed to cooperate regardless of others’ behavior. Instead, EI is associated with the capacity to respond flexibly to others’ strategies and to the interaction context in order to maximize long-term gains – even when this means competing rather than cooperating.     

帕金森病诊断标记物系统回顾与展望

本篇综述总结了帕金森病的诊断、鉴别诊断和病程监测的各领域的生物学标记物的研究进展。其中重点介绍了神经影像学和生物化学领域的生物学标记物,也是当前研究较为成熟的两大领域。神经影像学标记物以多巴胺能影像及非多巴胺能影像为代表,生物化学标记物为包括a一突触核蛋白在内的多种蛋白和激素,两者的结合能够有效提高疾病诊断的特异性和灵敏性。同时文章还介绍了当前研究的热点——帕金森病的前驱诊断手段,即在疾病典型的运动症状和非运动症状出现前便可预测帕金森病的诊断手段。     

炎症性肠病的药物治疗现状及进展

炎症性肠病（IBD）病程迁延反复,影响患者生活质量,耗费卫生资源。虽然传统药物如5-氨基水杨酸、糖皮质激素、免疫抑制剂等仍是目前治疗主流,但是大量有关发病机制的研究以及循证医学的发展对IBD的治疗产生了积极的推进作用。IBD的治疗正步入免疫调节的生物学时代,多种新型生物制剂的出现为IBD的治疗提供了新的策略和选择。现就目前IBD药物治疗现状以及最新进展进行综述,以期对临床IBD治疗提供参考。     

Zuckerkandl结节在甲状腺手术中对上甲状旁腺的定位与保护

探讨Zuckerkandl结节（ZT）在甲状腺手术中对上甲状旁腺的定位与保护作用.对我院2011年10月至2013年1月在我院行甲状腺手术患者351例进行回顾分析,结果显示,ZT在左侧叶甲状腺的发生率为89.0％（268/301）,右侧叶中的发生率为87.3％（254/291）,共计5例患者出现术后甲状旁腺功能一过性下降,未有永久性甲状旁腺功能损失患者出现.ZT为甲状腺手术中探查上甲状旁腺提供了新的途径与解剖标志,值得引起甲状腺外科医生的关注.     

阿尔茨海默病的诊治新进展

流行病学数据的更新表明阿尔茨海默病（A D ）已成为全球健康问题。早期应用生物标志物的AD新诊断标准广泛应用和临床试验不断失败的鲜明反差提示AD治疗的艰巨性。AD和其他慢性疾病的共病研究不断深入。生活方式干预作为非药物治疗备受重视。     

Client as expert: A Delphi poll of clients’ subjective experience of therapeutic alliance formation variables

This study extends prior research that identified client-derived variables believed to contribute to therapeutic alliance development. Forty-two clients participated in a three-round-modified Delphi poll in which the subjective importance of 74 client-derived, common alliance formation variables was rated using a six-point scale. Participants consensually identified 23 variables as highly important, five as moderately important and three as low in importance to the formation of a strong alliance. Variables related to validation and asking about parts of the client’s life other than the presenting concern were considered as most important by at least one-third of the sample. Limitations of the study are presented and implications for theory, measurement, practice and future research are briefly discussed.     

On the logical structure of de Finetti's notion of event

This paper sheds new light on the subtle relation between probability and logic by (i) providing a logical development of Bruno de Finetti's conception of events and (ii) suggesting that the subjective nature of de Finetti's interpretation of probability emerges in a clearer form against such a logical background. By making explicit the epistemic structure which underlies what we call Choice-based probability we show that whilst all rational degrees of belief must be probabilities, the converse doesn't hold: some probability values don't represent decision-relevant quantifications of uncertainty.