Time-course of hemispheric preference for processing contralateral relevant shapes: P1pc, N1pc, N2pc, N3pc

A most sensitive and specific electrophysiological indicator of selective processing of visual stimuli is the N2pc component. N2pc is a negative EEG potential peaking 250 ms after stimulus onset, recorded from posterior sites contralateral to relevant stimuli. Additional deflections preceding or following N2pc have been obtained in previous studies, possibly produced by specific stimulus features or specific prime-target sequences. To clarify the entire time-course of the contralateral- ipsilateral (C-I) difference recorded from the scalp above visual cortex in response to left-right pairs of targets and distracters, C-I differences were here compared between two types of stimuli and between stimuli that were or were not preceded by masked neutral primes. The C-I difference waveform consisted of several peaks, termed here P1pc (60-100 ms after target onset), N1pc (120-160 ms), N2pc (220-280 ms), and N3pc (360-400 ms). Being markedly enhanced when stimuli were preceded by the neutral primes, P1pc may indicate a response to stimulus change. Also, when stimuli were primed, N2pc reached its peak earlier, thereby tending to merge with N1pc. N3pc seemed to increase when target discrimination was difficult. N1pc, N2pc, and N3pc appear as three periods of one process. N3pc probably corresponds to L400 or SPCN as described in other studies. These observations suggest that the neurophysiological basis of stimulus-driven focusing of attention on target stimuli is a process that lasts for hundreds of milliseconds, with the relevant hemisphere being activated in an oscillating manner as long as required by the task.     

言语和非言语信号加工的早期分离——来自ERP研究的证据

利用128导事件相关电位技术,对19名正常被试在言语、峰鸣声和音乐刺激上产生的脑电早期外源性成分N1进行了考察。实验结果发现,在音素条件和蜂鸣声条件下,左侧额叶N1波幅显著高于右侧。偶极子溯源分析发现音素条件和蜂鸣声条件下的偶极子都位于左脑额叶,而音乐条件下的两个偶极子位于右脑额叶。证明范畴属性对信号加工大脑半球优势的影响在加工的早期就开始发挥作用。     

Taxicab Correspondence Analysis

Taxicab correspondence analysis is based on the taxicab singular value decomposition of a contingency table, and it shares some similar properties with correspondence analysis. It is more robust than the ordinary correspondence analysis, because it gives uniform weights to all the points. The visual map constructed by taxicab correspondence analysis has a larger sweep and clearer perspective than the map obtained by correspondence analysis. Two examples are provided. This research was financed by the Natural Sciences and Engineering Research Council of Canada. The author thanks Serge Vienneau for his help regarding the graphical displays, and also thanks the editor, associate editor, and two reviewers for their constructive comments.     

Introduction

The place of philosophy in Iranian society is prominent. Philosophy is discussed in popular media as well as specialized journals, and in seminaries, research centers, and universities. Philosophy in Iran is often divided into Western and Islamic. Sometimes these are taken to be rivals. The methods of instruction differ to some extent, as well as the languages needed for advanced study. The question of the nature of Islamic philosophy is itself a controversial topic in Iran, and positions on this issue are often driven by ideological trends. The study of philosophy in the Islamic seminaries has its own history. Today Islamic philosophy may be considered a philosophical tradition that is being carried on with increasing interaction with the study of Western philosophy in Iran.

Living with Multiple Endocrine Neoplasia Type 1: Decent Care-Insufficient Medical and Genetic Information A Qualitative Study of MEN 1 Patients in a Swedish Hospital

This qualitative study explores how 29 Swedish patients with Multiple Endocrine Neoplasia type 1 (MEN1) experience living with the condition, appraisal of the clinical follow-up program, and surveys their future expectations. The aim of this study is to build knowledge about this patient group in order to provide optimal care. The participants describe physical, psychological, and social limitations in their daily activities and how these limitations influence quality of life. Our findings indicate that a majority of patients have adjusted to their situation, describing themselves as being healthy despite physical symptoms and treatment. The participants received decent care in the clinical follow-up program, - however, greater effort should be put into patient information. These patients might benefit from genetic counseling. Health professionals involved should recognize their potential impact and influence on a patient’s ability to adjust to these circumstances. Antonovsky`s Sense of Coherence theory is used to discuss these findings.     

Emotionally controlled decision-making and a gene variant related to serotonin synthesis in women with borderline personality disorder

The Iowa Gambling Task (IGT) was used to examine (i) social decision-making in women with borderline personality disorder (BPD), and (ii) the relationship between impaired decision-making and the tryptophan hydroxylase-1 (TPH-1) gene, involved in serotonin synthesis. Forty-two women with BPD and a history of suicide attempts were genotyped, and the frequency of a TPH-1 haplotype previously uniquely associated with BPD was calculated. The BPD group scored significantly lower than a control group in the IGT. Furthermore, the TPH-1 haplotype displayed a significantly higher frequency in BPD participants with impaired decision making, compared to BPD participants with normal scores. These findings suggest that impaired decision-making as determined by the IGT is a feature of BPD and may be (i) associated with serotonin dysfunction, and (ii) possibly relevant for suicidal behavior.     

<Emphasis Type="Italic">Special Topic:</Emphasis> Confucian and Christian Conceptions of Creativity

In this article the concept of God as creativity (rather than as “the Creator”) is explored. Though creativity is a profound mystery to us humans, it is a plausible concept today because of its interconnectedness with the belief that our cosmos is evolutionary: new orders of reality come into being in the course of time. Three modalities of creativity are explored here: the initial coming into being of the universe (the Big Bang); the creativity manifest in evolutionary processes; the human creation of culture. It is suggested that this creativity itself should be thought of as God: God is creativity. Thus God-talk is given a referent that is specifiable in terms of today’s understandings of the world and the human. God remains a profound mystery here, but one with a significant place in our modern understanding of the world and human life. This article includes text and ideas taken from my book, In the beginning…Creativity (Kaufman 2004).     

MARTIN RÁZUS: Literary and Philosophical Reflections on Morality1

Martin Rázus (1888–1937) was one of the most important personalities of Slovak Lutheran social, political, cultural, literary, and intellectual life during the first half of the twentieth century. First, I examine the picture of Slovak rural morality portrayed in the works of Rázus, particularly his 1929 novel Svety[Worlds], in which Rázus presents the morality of the people in the Slovak countryside from the beginning of the twentieth century until the end of the 1920s. Second, as the ethical and moral issues of life are crucial topics of Rázus's philosophical and ethical reasoning, I examine Rázus's ethical treatise Argumenty[Arguments] (1932), in which he develops, explains, and philosophically justifies many of his ideas concerning the ethics and morality expressed in his literary works and political and religious essays.     

Trading relations in the perception of speech by 5-year-old children

Five-year-old children were tested for perceptual trading relations between a temporal cue (silence duration) and a spectral cue (F₁ onset frequency) for the “say-stay” distinction. Identification functions were obtained for two synthetic “say-stay” continua, each containing systematic variations in the amount of silence following the /s/ noise. In one continuum, the vocalic portion had a lower F₁ onset than in the other continuum. Children showed a smaller trading relation than has been found with adults. They did not differ from adults, however, in their perception of an “ay-day” continuum formed by varying F₁ onset frequency only. The results of a discrimination task in which the two acoustic cues were made to “cooperate” or “conflict” phonetically supported the notion of perceptual equivalence of the temporal and spectral cues along a single phonetic dimension. The results indicate that young children, like adults, perceptually integrate multiple cues to a speech contrast in a phonetically relevant manner, but that they may not give the same perceptual weights to the various cues as do adults.