应用分子靶向治疗的时机选择

分子靶向药物的出现显示出肿瘤治疗传统模式的重要进展。与传统放疗、化疗相比,分子靶向治疗因其特异性高、不良反应轻微,在恶性肿瘤个体化治疗中扮演重要角色。十五年来,分子靶向药物的出现,给肿瘤的治疗模式带来重大改变,也给临床医生带来新的挑战。准确把握分子靶向药物应用时机,获得最大临床效果,已成为肿瘤治疗领域关注热点。本文就非小细胞肺癌、消化系统肿瘤、乳腺癌、肾癌治疗中分子靶向药物如何选择应用时机进行阐述。     

A brief thought on the future of global ethics: military robots and new food technologies

To deal with an uncertain future, global ethics as an academic endeavour might consider a common value we all share, such as sustainability, which acts as an all-encompassing term to indicate our future direction. Technologies of the near future that are currently in development hold problems and promise, and are clear subjects for the ethics of sustainability at a global level. Autonomous military combat robots, insects as food (entomophagy) and in vitro synthetically grown meat are significant cases. Such robots might in fact serve injustice and work against sustainability, and such novel food technologies may hold hope for promoting sustainability and global justice.     

Multiple-choice testing as a desirable difficulty in the classroom

We examined whether the power of tests as learning events, frequently demonstrated in the laboratory, would also occur in a large undergraduate course. Our goals were to determine: if learning of information tested on multiple-choice quizzes administered across the course would be enhanced compared to non-tested control information; and what the effects of quizzing would be for the learning of information conceptually related to the tested information but not itself tested on the quizzes. Given that retrieval practice can have positive (testing effect) and negative consequences (retrieval-induced forgetting), our concern was that the learning and later retention of non-tested conceptually related information might be impaired by the multiple-choice quizzes. Importantly, learning benefits were found for both types of information on the final exam, indicating that quizzing within a course can enhance not only the learning of specifically tested information, but the learning of non-tested conceptually related information as well.     

Empowering Muslim children’s spirituality in Malay Archipelago: integration between National Philosophical Foundations and Tawakkul (trust in God)

Multiple studies indicated that children raised to be spiritual were found to be happier, have more resilience and positive outlook towards life events. This paper attempts to explore and integrate the value of spirituality and religious practices. It is approached through the understanding and application of the tawakkul (trust in God) concept, as perceived from an Islamic viewpoint. This aspect is explored through the consolidation of the ‘believing in God’ component, as highlighted in the National Philosophical Foundations in Brunei, Indonesia and Malaysia to tawakkul. It will further seek to find the prospect of empowering Muslim children’s spirituality through such integration. This theoretical paper is based on the Islamic foundations and characteristics; its implementation and implications. The outcome illustrates indication of ‘divine involvement’ as the main essence of tawakkul; resulting sustainable religious, spiritual and moral enhancement. Moreover, an internalised and implicit form of tawakkul should be encouraged to promote self-understanding.     

Same-sex unions in Islam

The objective of this paper was to streamline the case for Muslim same-sex unions that was comprehensively made in Jahangir and Abdullatif (2016). Additionally, we try to address same-sex unions on the basis of non-binary gender, gender expression and sexual orientation. Based on our work, we argue that the case for Muslim same-sex unions can be made on the basis of broad principles of human dignity and affection and therefore through marriage or through the specific arguments of repelling harm and legal authority. In this regard, going beyond the overarching Islamic value of human dignity, we specifically argue that the case for same-sex unions can be anchored on verse 4:28 on facilitating a legal outlet for sexual expression.     

Creative Interventions for Teaching Empathy in the Counseling Classroom

Empathy is a foundational, necessary component of successful counseling. Relaying an understanding of empathy, including the components and science behind the phenomenon, is critical to the development of counselors-in-training. In addition, creative practice is a pillar of professional counseling, and is linked to experiential learning and meaningful integration of new knowledge in counselor education. The purpose of this article is to provide a review of the definitions of empathy, provide current literature on the science of empathy, and discuss specific creative interventions to use within counseling courses to increase empathic knowledge and skills.     

Staff and Administrators’ Perceptions of Music Therapy with Acute Care Mental Health Inpatients: A Qualitative Investigation

The purpose of this qualitative study is to understand staff members’ and administrators’ perceptions of group-based music therapy in an acute care mental health setting. The researcher conducted semi-structured interviews with six experienced administrators and unit staff who were familiar with music therapy. Using an inductive approach to thematic analysis, the author identified six themes: (a) music constitutes an important role in patients’ lives, (b) patient-centricity and competence of the music therapist, (c) music therapy uniquely engages the patient with music, the music therapist, and peers, (d) music therapy shifts patients’ focus from internal to external, (e) music therapy is a normalizing experience that facilitates interaction, and (f) music therapy provides optimal conditions for cognitive, affective, and behavioral change. Implications for clinical practice, suggestions for future research, and limitations of the study are provided.     

Art Making and Identity Formation in Children and Adolescents with Differing Social Behaviors

Not everyone develops social behaviors and interaction skills in an expected manner. This study explored the relationship between art making and identity formation in children and adolescents who were identified as having differing social behaviors. In three small group settings, 17 participants created abstract self-portraits from modeling compound and responded to questions about their self, self-concept, and self-esteem. From this, a model was created to describe identity formation as it relates to the relationships between social environment, desired occupations and activities, and creativity. Practice guidelines are proposed for those who provide children and adolescents with opportunities to make art as part of sessions aimed to promote the development of a healthy self-concept.     

What’s Your Style? Preliminary Validation of the Gaming Styles Questionnaire

Within-group differences amongst gamers must be considered when studying the psychological correlates of gameplay. A conceptual framework, whereby gaming may be treated as a means to other ends—such as coping with boredom or bonding with friends—or as an end in itself, was the basis upon which the Gaming Styles Questionnaire was developed. Factor analysis and criterion-group validity, based on data obtained from a heterogeneous sample of gamers, offered support to a continuum of gamers, ranging from those for whom gaming is a means to other ends to those for whom gaming is an end in itself. Although age did not correlate with gaming style, men’s endorsement of gaming as an end in itself was stronger than women’s.