Is Mozi a utilitarian philosopher?

In this essay I argue that Mozi’s philosophy is anything but utilitarianism by way of analysing four ethical theories. Utilitarianism is an ethics in which the moral subject is an atomic individual human being, and its concern is how to fulfill the interests of the individual self and the social majority. Confucian ethics is centered on the notion of the family and its basic question is that of priority in the relationship between the small self and the enlarged or collective self. Opposite to these two moral theories is Mozi’s ethics: The interests that Mozi is primarily concerned with are not the interests of my individual self or my collective self, but the interests of the other. The fulfillment of the material needs of the other is my moral obligation. The arguments are centered on the three basic concepts, “the I,” “the we,” and “the other.” The significance of Mozi’s thought in modern or postmodern context lies in its striking resemblance to the philosophy of a contemporary western philosopher, Levinas. In both Mozi and Levinas, there is a suspension of utilitarianism. __________ Translated from Zhongguo Zhexue Shi 中国哲学史 (History of Chinese Philosophy), 2005 (1)     

对临床药学发展的几点思考

经过30余年的探索与实践,我国的临床药学发展已初具规模,其开展的必要性和重要性得到社会各界的肯定。但就开展程度而言,临床药学仍为一门年轻的学科,其内容和体系均凾待完善。在回顾过去,总结经验教训的基础上,我们有针对性地提出了一些关于临床药学体系建设的建议,期望对我国临床药学工作的全面开展有所帮助。     

重症加强治疗病房鲍曼不动杆菌的耐药性分析

为了了解重症加强治疗病房标本分离出的鲍曼不动杆菌对常用抗生素耐药性,指导临床用药。回顾性调查分析2009年1月至2010年1月大连医科大学附属第一医院重症加强治疗病房标本分离的鲍曼不动杆菌对常用抗生素药敏结果。发现目前重症加强治疗病房标本分离的鲍曼不动杆菌已呈现出十分严重的耐药性,应引起高度重视。     

Are preference reversals reduced when made explicit?

Previous research has shown that preferences for options, such as gambles, can reverse depending on the response mode. These preference reversals have been demonstrated when tasks were performed sequentially. That is, subjects completed one task before beginning another. In an attempt to eliminate preference reversals, we asked subjects to perform tasks simultaneously. That is, subjects made two types of responses for each pair of gambles before evaluating the next pair. In the condition with no financial incentives, preference reversal rates were slightly reduced. In another condition, subjects were paid for their participation and they were allowed to play a gamble with real monetary compensation. A gamble pair was randomly selected, and if a subject's responses in the two tasks were consistent for that pair, he or she was allowed to play the ‘preferred’ gamble. Otherwise, the experimenter selected the gamble from the pair. With these financial incentives, systematic preference reversals were eliminated for two of the three task combinations. Preference reversals continued to occur for attractiveness ratings versus selling prices, although, even for that pair of tasks, the reversal rate was significantly reduced. For all three task pairs, preference orders from the two tasks appeared to merge into more consistent orders.     

Unit-price analysis of opioid consumption by monkeys responding under a progressive-ratio schedule of drug injection.

Several reports have indicated that drug consumption in self-administration procedures is a function of the ratio of the instrumental requirement to the dose of drug, a quantity termed unit price. We evaluated three predictions from this unit-price model in a reanalysis of data on opioid self-administration in rhesus monkeys responding under a progressive-ratio schedule (Hoffmeister, 1979). We evaluated whether consumption was inversely related to unit price, and compared the goodness of fit of an equation devised by Hursh, Raslear, Shurtleff, Bauman, and Simmons (1988) to that of a linear model predicting consumption as a function of dose. We also tested whether consumption was constant when the same unit price was comprised of different combinations of dose and instrumental requirement. Consumption declined overall as unit price increased. The equation devised by Hursh et al. and the linear model based on dose fit the data equally well. Drug consumption was not uniform at a given unit price. The analyses suggest limits on the unit-price model as a characterization of drug consumption.     

Normalized demand for drugs and other reinforcers.

The concepts of behavioral economics have proven to be useful for understanding the environmental control of overall levels of responding for a variety of commodities, including reinforcement by drug self-administration. These general concepts have implications for the assessment of abuse liability and drug abuse intervention and the formulation of public policy on drug abuse. An essential requirement is the ability to compare the demand for different drugs directly in order to assess relative abuse liability, and to compare demand for the same drug under different environmental and biological interventions to assess their ability to reduce demand. Until now, such comparisons were hampered by the confounding effect of varying drug doses and potencies that prevent quantitative comparisons of demand elasticity--sensitivity of consumption and responding to the constraint of price (effort). In this paper we describe a procedure to normalize demand-curve analysis that permits dose- and potency-independent comparisons of demand across drugs. The procedure is shown to be effective for comparing drug demand within and across the drug classes. The technique permits a quantitative ordering of demand that is consistent with the peak levels of responding maintained by the drugs. The same technique is generalized for the comparison of other types of reinforcers under different biological conditions.     

Behavior of rats under fixed consecutive number schedules: effects of drugs of abuse.

Four rats responded under a simple fixed consecutive number schedule in which eight or more consecutive responses on the run lever, followed by a single response on the reinforcement lever, produced the food reinforcer. Under this simple schedule, dose-response curves were determined for diazepam, morphine, pentobarbital, and phencyclidine. The rats were then trained to respond under a multiple fixed consecutive number schedule in which a discriminative stimulus signaled when the response requirement on the run lever had been completed in one of the two fixed consecutive number component schedules. Under control conditions, the percentage of reinforced runs under the multiple-schedule component with the discriminative stimulus added was much higher than the percentage of reinforced runs under the multiple-schedule component without the discriminative stimulus. All of the drugs decreased the percentage of reinforced runs under each of the fixed consecutive number schedules by increasing the conditional probability of short run lengths. This effect was most consistently produced by morphine. The drugs produced few differences in responding between the multiple fixed consecutive number components. Responding under the simple fixed consecutive number schedule, however, was affected at lower doses of the drugs than was responding under the same fixed consecutive number schedule when it was a component of the multiple schedule. This result may be due to the difference in schedule context or, perhaps, to the order of the experiments.     

Comorbidity of drug abuse treatment

Research has suggested that comorbidity, the concurrence of substance abuse disorders with other psychiatric disorders, may have prognostic value and important implications for the treatment of substance abuse. Knowledge of the prevalence of comorbid disorder is important because it will enable treatment services to be appropriately configured and designed for clinical drug treatment populations. The form and duration of comorbidity may be influenced by a variety of factors, which include the class of drug being abused, the duration of drug use, the individual sensitivity to drug effects, and whether the drug effects are acute or due to withdrawal or residual conditions. This paper addresses three important scientific questions: (1) What is the prevalence of comorbid disorders in a drug abuser population? (2) What is the stability of psychiatric diagnoses in a drug abuser population? (3) Does the existence of a comorbid disorder influence the outcome of drug abuse treatment?     

Taboo Trade-offs: Reactions to Transactions That Transgress the Spheres of Justice

Taboo trade-offs violate deeply held normative intuitions about the integrity, even sanctity, of certain relationships and the moral-political values underlying those relationships. For instance, if asked to estimate the monetary worth of one's children, of one's loyalty to one's country, or of acts of friendship, people find the questions more than merely confusing or cognitively intractable: they find such questions themselves morally offensive. This article draws on Fiske's relational theory and Tetlock's value pluralism model: (a) to identify the conditions under which people are likely to treat trade-offs as taboo; (b) to describe how people collectively deal with trade-offs that become problematic; (c) to specify the conceptual components of moral outrage and the factors that affect the intensity of reactions to various explicit trade-offs; (d) to explore the various strategies that decision-makers—required by resource scarcity and institutional roles to confront taboo trade-offs—use to deflect the wrath of censorious observers; (e) to offer a method of dispute resolution based on pluralism.     

Super Pill is Less Effective than an Ordinary Mint in Altering Subjective Psychological Feeling States within a Few Minutes

Expectations shape human behavior. Initial drug use might be associated with information-based expectations. In this study, we presumed that changes in affect and perceived physical wellbeing will be stronger after receiving an active placebo (Tic Tac mint; n = 40), than a pure placebo (inert pill; n = 40) given as a mood-enhancing “super pill.” After baseline measures, participants completed a treatment-expectancy scale, ingested the mint/super pill, and attended to the effects over 3-minutes. Subsequently, they completed again the psychological tests. Expectancy scores were positive and did not differ between the groups. The pure placebo group increased in physical wellbeing but less than the active placebo group, which also showed an increase in positive affect. Negative affect decreased in both groups. The Tic Tac produced greater affective changes than the pure placebo. Since these are new findings on the ultra-short placebo effects on affect, the results might have relevance for drug-use studies.