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111.
The ethical issues in conducting research on preventing HIV infection are among the most complex of any area of human subjects
research. This article is an update of a 1987 article that addressed potential conflicts between research design and ethics
with respect to AIDS prevention among injecting drug users. The present article reviews current ethical issues that arise
in the design and conduct of HIV/AIDS prevention research focused on injecting drug users.
Disclaimer: The content of this publication is solely the responsibility of the authors and does not necessarily represent
the views of the Beth Israel Medical Center or Johns Hopkins University. 相似文献
112.
Virginia Gil-Rivas M. Douglas Anglin Jeffrey J. Annon 《Journal of psychopathology and behavioral assessment》1997,19(2):161-174
This study examined the patterns of drug use and criminal activities among Latino arrestees. The findings indicate that while the prevalence of drug use at time of arrest, and in the prior 12 months were significantly lower for Latinos compared to Whites and Blacks, drug use still is of concern for this ethnic group. Almost 50% of Latinos reported drug use in the last year, and more importantly, they were more likely to report using dangerous drugs such as cocaine, heroin, and PCP than any other ethnic group. These findings are even more alarming considering that, for the most part, Latino drug users were treatment-naive, and that less than half perceived a need for drug treatment. Regarding criminal activities, Latinos were less likely to have a history of prior arrests and to have been arrested in the year prior to the interview than any other ethnic group. Interestingly, those immigrants who have resided in the U.S. for less than 1 year were significantly more likely to have been charged with drug-related crimes. U.S. born Latinos were more likely to have been arrested for property crimes, while Central American immigrants were more likely than any other Latino group to have been arrested for violent and domestic violence crimes. Treatment and policy implications of these findings are discussed. 相似文献
113.
Facilitation of human tobacco self-administration by ethanol: a behavioral analysis. 总被引:3,自引:0,他引:3 下载免费PDF全文
R R Griffiths G E Bigelow I Liebson 《Journal of the experimental analysis of behavior》1976,25(3):279-292
The effect of ethanol on the cigarette smoking of alcoholic subjects was studied in a residential laboratory. During daily 6-hr sessions, cigarettes were obtained either by request to the ward staff or by operation of a lever (fixed-ratio 5 or 10). In a mixed sequence across days, sessions involved ingestion of either vehicle (orange juice or vehicle plus ethanol (133.7 g). During ethanol sessions, the rate of cigarette smoking increased from 26% to 117% of vehicle levels. A series of control studies eliminated a number of potential behavorial mechanisms for the observed effect and indicated that the ethanol-induced increase in cigarette smoking occurred under a variety of experimental conditions: (1) when smoking could not occur concurrently with ethanol or vehicle consumption; (2) when subjects were not allowed to socialize; (3) when ingestion of ethanol or vehicle was scheduled for a number of consecutive days; (4) when various doses of ethanol were administered under blind conditions. In control experiments, weighing unsmoked tobacco and counting the number of puffs per cigarette indicated the effect was not due to smoking less of each cigarette. The effect was not limited to the experimental sessions alone, since total daily smoking was higher on ethanol days than vehicle days. 相似文献
114.
115.
Phencyclidine discrimination in the pigeon using color tracking under second-order schedules 总被引:7,自引:7,他引:0 下载免费PDF全文
D. E. McMillan D. A. Cole-Fullenwider W. C. Hardwick G. R. Wenger 《Journal of the experimental analysis of behavior》1982,37(1):143-147
Pigeons were trained to track different key colors, depending on whether they had been injected with phencyclidine or saline prior to the session. A second-order schedule was used to generate large numbers of responses prior to the initial food delivery. The procedure offers several advantages over traditional procedures for studying drug discrimination. 相似文献
116.
Melvin R. Novick 《Psychometrika》1980,45(4):411-424
In this paper, modern statistics is considered as a branch of psychometrics and the question of how the central problems of statistics can be resolved using psychometric methods is investigated. Theories and methods developed in the fields of test theory, scaling, and factor analysis are related to the principle problems of modern statistical theory and method. Topics surveyed include assessment of probabilities, assessment of utilities, assessment of exchangeability, preposterior analysis, adversary analysis, multiple comparisons, the selection of predictor variables, and full-rank ANOVA. Reference is made to some literature from the field of cognitive psychology to indicate some of the difficulties encountered in probability and utility assessment. Some methods for resolving these difficulties using the Computer-Assisted Data Analysis (CADA) Monitor are described, as is some recent experimental work on utility assessment.1980 Psychometric Society presidential address.I am indebted to Paul Slovic and David Libby for valuable consultation on the issues discussed in this paper and to Nancy Turner and Laura Novick for assistance in preparation.Research reported herein was supported under contract number N00014-77-C-0428 from the Office of Naval Research to The University of Iowa, Melvin R. Novick, principal investigator. Opinions expressed herein reflect those of the author and not those of sponsoring agencies. 相似文献
117.
A simple model for the utility of gambling 总被引:2,自引:0,他引:2
Peter C. Fishburn 《Psychometrika》1980,45(4):435-448
A model of the utility of gambling is presented in a modified von Neumann-Morgenstern format. Axioms imply a utility function that preserves preferences between sure things and between gambles. The addition of a utility of gambling term to the expected utility of a gamble preserves preference comparisons between gambles and sure things. Aspects of the utility of gambling are noted, and comparisons are made to standard concepts of risk attitudes.The author is indebted to Joseph Sani for valuable discussions on the topic of this paper. 相似文献
118.
David J. Kolko Alan D. Sirota Peter M. Monti Ronald M. Paolino 《Journal of psychopathology and behavioral assessment》1985,7(2):135-144
The present research was concerned with identifying and validating the problematic interpersonal situations of male veteran drug addicts. In Study I, 20 addicts self-monitored the situations with which they had difficulty coping and their associated characteristics throughout a 2-week period. Fifty situations were obtained and then rewritten into specific interpersonal scenarios. In Study II, a second group of 36 addicts and a comparison group of 20 disabled veterans rated the commonality and difficulty of each scenario along seven-point scales. Univariate ANOVAs found that five scenarios received ratings greater than four on both scales and were associated with significantly higher ratings by the addicts. These preliminary scenarios may serve as role-play situations during social-skills assessment and training and may provide further information regarding the interpersonal determinants of relapse occasioned in the natural environment. The need for controlled comparison studies using behavioral measures and an overall improvement in the methodological rigor of research in the area is discussed.The authors acknowledge the editorial comments of Ted D. Nirenberg, Ph.D., on an earlier draft of this paper. Portions of these data were presented at the Fifth World Congress on Behavior Therapy, Washington, DC. 相似文献
119.
Mark K. Greenwald 《Journal of applied behavior analysis》2008,41(4):603-607
A positive reinforcement contingency increased opioid abstinence during outpatient dose tapering (4, 2, then 0 mg/day during Weeks 1 through 3) in non‐treatment‐seeking heroin‐dependent volunteers who had been maintained on buprenorphine (8 mg/day) during an inpatient research protocol. The control group (n = 12) received $4.00 for completing assessments at each thrice‐weekly visit during dose tapering; 10 of 12 lapsed to heroin use 1 day after discharge. The abstinence reinforcement group (n = 10) received $30.00 for each consecutive opioid‐free urine sample; this significantly delayed heroin lapse (median, 15 days). 相似文献
120.
通过对本地一所三级甲等医院进行的围手术期抗菌药物的干预对照研究,用SPSS软件对470个手术病例的调查资料进行了统计分析,加强抗菌药物的用药管理及进行用药干预,能在对住院时间和手术切口感染率无影响的同时,明显降低手术病例的药品费用,特别是抗茵药品的费用,减轻患者负担。 相似文献