背景性渴求与事件性渴求:区分心理渴求对尼古丁成瘾的不同作用路径

大量研究发现心理渴求机制的紊乱是尼古丁成瘾的核心机制之一。线索暴露是探索心理渴求与尼古丁成瘾关系的重要研究范式。但最近研究者提出该范式较难区分事件性渴求与背景性渴求,导致无法清楚定位渴求在尼古丁成瘾中扮演的角色。通过对以往文献的回顾,对不同成瘾概念、作用机制和生理基础进行对比分析,认为事件性渴求与背景性渴求两者在维持成瘾行为上的确存在不同的作用路径。未来研究应改进实验范式,分别探讨两种心理渴求与尼古丁成瘾的内在联系,完善心理渴求与尼古丁成瘾的关系模型,为尼古丁成瘾的治疗和干预等方法提供一定的理论依据。     

A behavioral economic analysis of concurrently available money and cigarettes.

In economic terms, consumption of a reinforcer is determined by its price and the availability and price of other reinforcers. This study examined the effects of response-requirement (i.e., price) manipulations on the self-administration of two concurrently available reinforcers. Six cigarette smokers participated in 4-hr sessions in which money and puffs on a cigarette were concurrently available according to fixed-ratio schedules of reinforcement. Once stable responding was obtained with both reinforcers available at Fixed Ratio 100, the response requirement for one reinforcer was systematically varied (Fixed Ratio 1,000 and 2,500), while the other reinforcer remained scheduled at Fixed Ratio 100. Increasing the fixed-ratio size for a reinforcer decreased its consumption, with a greater decrease occurring for monetary reinforcement. This finding was quantified in economic terms as own-price elasticity, with elasticity coefficients greater for money than cigarettes. The effects of fixed-ratio size on response output also differed across the two reinforcers. Although greater responding occurred for money at Fixed Ratio 100, increases in fixed-ratio size (for money) decreased responding for money, whereas the same increase in fixed-ratio size (for puffs) increased responding for puffs. Finally, increasing the fixed-ratio size for one reinforcer had little effect on consumption of the other concurrently available reinforcer. This finding was quantified as cross-price elasticity, with elasticity coefficients near 0.0 for most subjects, indicating little or no reinforcer interaction. The results indicate that the reinforcing effects of cigarettes and money in the setting studied here differed, and that the effects produced by changing the price of one reinforcer did not interact with the consumption of the other concurrently available reinforcer.     

心理戒毒实验研究

1问题以往对毒品依赖者的临床治疗,偏重于躯体依赖的药物戒治,实践表明,克服戒断反应并不困难。然而,戒断反应消除了,毒瘾却并没戒除,表现是：复吸率非常高──达98％。如此之高的复吸率引起我们的注意：反复吸毒到底是一个生理问题还是一个心理问题？吸毒者在反复吸毒过程中追求的是什么？由此,导向另一个更深层次的问题：“戒毒要戒掉什么？”我们就此问题进行了调查,调查对象包括广州、探圳等戒毒所收治的150名吸毒者。结果显示：（1）开始吸毒时有非常强烈的情绪体验,这种情绪体验的强烈程度和愉快程度远远超过性交的体验。随…     

在批判与建构之间--黑格尔历史理念:意义·批判·反思

本文从理性、自由、国家观、理性-非理性动力结构、两个世界的历史理念等方面解读了黑格尔历史哲学的意义或启示;阐述了它自身存在的问题和由此受到的批判或挑战。本文从批判与建构的双重维度出发,重新审视、反思了在批判黑格尔历史哲学的过程中存在的问题和教训。     

Completeness Theorems via the Double Dual Functor

The aim of this paper is to apply properties of the double dual endofunctor on the category of bounded distributive lattices and some extensions thereof to obtain completeness of certain non-classical propositional logics in a unified way. In particular, we obtain completeness theorems for Moisil calculus, n-valued Łukasiewicz calculus and Nelson calculus. Furthermore we show some conservativeness results by these methods. This revised version was published online in June 2006 with corrections to the Cover Date.     

Drug effects on fixed-interval responding with pause requirements for food presentation.

In pigeons performing under a multiple schedule of food presentation, low key-pecking rates (0.18 to 0.29 responses per second) were maintained during 3-min fixed-interval components by requiring a 4-, 5-, or 6-sec pause preceding the food-delivery response (tandem DRL), while higher rates (0.70 to 1.37 responses per second) were maintained in alternative fixed-interval components by requiring a pause of no more than 40 msec preceding the food-delivery response (tandem DRH). Thus, reinforcement density was equal but overall response rates markedly different in the two schedule components. Pentobarbital (3, 10 mg/kg) had effects on overall rates of responding consistent with a rate-dependency interpretation (low rates were increased while higher rates were decreased), but d-amphetamine (0.03 to 3 mg/kg) either failed to increase low overall rates in the tandem DRL components or increased them only slightly. Effects of both drugs on local responding within the fixed-intervals were always related in an orderly way to control response rate, but the extent of rate increases produced by d-amphetamine was modifed in some birds by pause requirements such that the drug increased comparable rates less when these occurred in the tandem DRL component than when they occurred in the tandem DRH components. Control rate is an important determinant of drug effects, independent DRH components. Control rate is an important determinant of drug effects, independent of reinforcement density maintaining rates, and independent of environmental influences, such as response-spacing requirements for food presentation, that can modify the extent of some drug-produced rate changes.     

弯曲时空理论与生物体DNA双螺旋结构

对爱因斯坦的"弯曲时空"理论与生物体DNA双螺旋结构的相关性进行了哲理性思考:控制生命时间程序的生物钟基因编码及调控细胞分裂的正、负向基因对应表达的严格时间程序,在DNA双螺旋结构上可能具有"时空弯曲"的原理.地球上不同经纬度地区的时间流行病学特征应该具有相对同时性.     

民众收入不公平感的机制与对策——基于参照依赖和损失规避双视角

近年来,贫富差距的不断加大已引起民众较为强烈的收入不公平感,而导致收入不公平感产生的一个主要原因是人们对自己收入所得不如他人的相对比较。本项目基于预期理论价值函数的参照依赖和损失规避双视角,对当前民众收入不公平感的形成机制与管理对策进行系列实证研究;采用心理测量、实验室实验和干预研究相结合的方法,并借助神经电生理的ERP技术和心理生理学的多导生理记录仪(SCR),以检验民众收入不公平感的自我-他人参照、单参照点-多参照点比较的整合性参照依赖框架;探索损失规避对多得不均等和少得不均等的非对称不公平感的根源性作用和神经生理机制;选取社区居民,操纵参照对象、参照点和得失框架,进行多轮次和多变量的干预研究,以探索减少民众收入不公平感的应对策略,并据此提出切实有效的管理对策。     

Word fluency performance and strategies in children with cochlear implants: age‐dependent effects?

Löfkvist, U., Almkvist, O., Lyxell, B. & Tallberg, I.‐M. (2012). Word fluency performance and strategies in children with cochlear implants: age‐dependent effects? Scandinavian Journal of Psychology 53, 467–474. Word fluency was examined in 73 Swedish children aged 6–9 years divided into two age groups, 6–7 and 8–9 years; 34 deaf children with cochlear implants (CI) (15 girls/19 boys) and 39 age‐matched children with normal hearing (NH) (20 girls/19 boys). One purpose was to compare the ability to retrieve words in two different word fluency tasks; one phonemically based (FAS letter fluency) and one semantically based (animal fluency). A second purpose was to examine retrieval strategies in the two tasks by conducting an analysis of clustering and switching of word sequences. In general we found that age was an important factor for word fluency ability, in both the CI and the NH groups. It was also demonstrated that children with CI aged 8–9 years retrieved significantly fewer words and used less efficient strategies in the retrieval process, especially on the phonemically based task compared to children with NH of the same ages, whereas children 6–7 years performed similarly in both groups regarding number of retrieved words and use of strategies. The results are discussed with respect to factors such as age differences in performance for children with CI, especially for the phonemically based task.