Persistent operational synchrony within brain default-mode network and self-processing operations in healthy subjects

Based on the theoretical analysis of self-consciousness concepts, we hypothesized that the spatio-temporal pattern of functional connectivity within the default-mode network (DMN) should persist unchanged across a variety of different cognitive tasks or acts, thus being task-unrelated. This supposition is in contrast with current understanding that DMN activated when the subjects are resting and deactivated during any attention-demanding cognitive tasks. To test our proposal, we used, in retrospect, the results from our two early studies (Fingelkurts, 1998; Fingelkurts et al., 2003). In both studies for the majority of experimental trails we indeed found a constellation of operationally synchronized cortical areas (indexed as DMN) that was persistent across all studied experimental conditions in all subjects. Furthermore, we found three major elements comprising this DMN: two symmetrical occipito-parieto-temporal and one frontal spatio-temporal patterns. This new data directly supports the notion that DMN has a specific functional connotation - it provides neurophysiologic basis for self-processing operations, namely first-person perspective taking and an experience of agency.     

Conversing while driving: The importance of visual information for conversation modulation

Multiple studies have shown an increased accident risk due to telephoning while driving. On the other hand, driving with passengers leads to a decreased accident risk. One explanation is a conversation modulation by passengers in cars which leads to a different conversation pattern which is not so detrimental to driving as that when phoning. A driving simulator study was conducted in order to examine this conversation modulation more closely and to find out more about the factors involved in this modulation, especially about the role of visual information available to the passenger. In a within-subject design the conversational patterns of 33 drivers and passengers in different in-car settings (passenger as usual, passenger without front view or passenger without view of the driver) were compared to a hands-free cell phone and to a hands-free cell phone with additional visual information either about the driving situation or the driver. Participants were instructed to have a naturalistic small-talk with a friend. Results of the drivers’ speaking behavior showed a reduction of speaking while driving. Compared to a conversation partner on the cell phone, a passenger in the car varies his speaking rhythm by speaking more often but shorter. Further analyses showed that this effect is also found with a cell phone when providing the conversation partner additional visual information either about the driving situation or the driver. This latter finding supports the idea that conversation modulation is not triggered by being in the car but by the visual information about the driver’s state and the driving situation.     

多属性决策任务中焦虑型个体的信息加工特点研究

该研究以多属性职业选项为材料,采用计算机化的信息板技术初步考察了焦虑型个体在多属性决策过程中的信息加工特点,结果表明焦虑型个体与非焦虑个体的决策过程有所不同。主要表现在与非焦虑型的决策者相比,焦虑型的被试在决策过程中对职业属性的加工时间更长,加工的信息也更多;在决策前后他们对完成决策任务的信心水平评估都很低,但是在搜索模式上焦虑型的决策者与非焦虑型的决策者没有差别。在研究的讨论部分对焦虑型个体决策过程中信息加工特点的原因进行了分析。     

Few Gender Differences Exist Between Women and Men with Chronic Fatigue Syndrome

Chronic fatigue syndrome (CFS) is generally considered to be a women's health issue, but the illness occurs also in men. The research objective of this study was to determine if illness patterns and functional status differed between the sexes. Because our own data showed that women with CFS have significantly more comorbid fibromyalgia or multiple chemical sensitivity than men, we eliminated patients with these comorbid conditions from our evaluation. Women with CFS were quite similar to men with CFS in terms of demographics, psychiatric status, functional status, and assessments of disability. Women reported more infectious/flu-like symptoms (represented by a factor derived from factor analysis) than men, but these differences were insignificant after controlling for other variables. Cluster analysis revealed that women were more likely than men to fall in the cluster characterized by symptom severity. Differences found were those of degree rather than of type; strikingly different illness patterns—suggestive of different pathophysiological processes between the sexes—were not found.     

The effect of product type on value linkages in the means‐end chain: implications for theory and method

Means‐end chain (MEC) theory proposes that consumer motivation can only be understood in terms of the hierarchical linkages between attributes, consequences and values. Other researchers have suggested a much more immediate impact of values on motivation. Seeking to explain these conflicting views, this research suggests and empirically tests the proposition that the role of values in consumer motivation differs by product type and also tests that the linkages are not affected by individual differences in the need for cognition. A sample of 191 consumers indicated their motivation to consume utilitarian and non‐utilitarian products using an adapted association pattern matrix technique. Responses were analysed using mixed‐design ANOVAs with planned comparisons. Results indicate significant differences related to product type in the role of values in consumer motivation. Limitations, implications for MEC theory and future research are discussed. Copyright © 2004 Henry Stewart Publications Ltd.     

Temporal dynamics in attention bias: effects of sex differences,task timing parameters,and stimulus valence

New methods of calculating indices from the dot-probe task measure temporal dynamics in attention bias or fluctuations in attention bias towards and away from emotional stimuli over time. However, it is unclear how task-specific parameters such as stimulus valence and stimulus onset asynchrony (SOA) as well as participant sex affect temporal dynamics in attention bias. To address this, male and female participants (N?=?106) completed either a fearful or happy face dot-probe task with four levels of SOA (84?ms, 168?ms, 336?ms, and 672?ms). Results suggest that temporal dynamics in attention bias are (1) greatest at the longest SOA, (2) greater in females, and (3) insensitive to stimulus valence. These findings indicate that participant sex and task timing, but not stimulus valence, are related to temporal dynamics in attention bias and should be considered in future studies utilizing this approach.     

幼儿在辨别过程中图形维度显著性的研究

采用Triad Classification法和等级图形模式研究了4～6岁幼儿在辨别过程中图形维度显著性效应。实验1让幼儿进行自由辨别任务,发现颜色显著性强于形状,局部特征的显著性强于整体特征;随被试年龄增长,整体特征和颜色的显著性逐渐增强;对维度显著性等级模式的信息加工比对整体局部特征等级模式的加工反应时长。实验2进行按指定标准来辨别的任务,发现仍然出现图形维度显著性效应。这些结果说明图形维度显著性效应可能是自动发生的,可能比整体局部特征的认知加工更复杂。     

证素辨证新体系的内容及科学意义

提取并规范50项辨证要素,构建起证素辨证新体系,是继承基础上的创新.证素的纲领性与组合的复杂性,是科学的认知论,符合中医辨证思维规律.     

关于医学人文关怀的几点思考

医学兼有自然科学和人文社会科学双重属性.其核心理念即人文精神决定了医疗服务必须体现人文关怀,这是高质量医疗服务和医学模式转换的必然要求,并且有助于减少医疗纠纷,提升医院的竞争力.