Comparison of hemispheric activation during mental word and rhyme generation using transcranial Doppler sonography

The Wada test is at present the method of choice for preoperative assessment of patients who require surgery close to cortical language areas. It is, however, an invasive test with an attached morbidity risk. By now, an alternative to the Wada test is to combine a lexical word generation paradigm with non-invasive imaging techniques. However, results of this approach are still not in complete agreement with the findings of the Wada test (r = .92; Knecht, Deppe, Ebner et al., 1998). We attempted to obtain a more distinct language lateralization with the development of a phonological rhyme generation paradigm based on pseudoword stimuli. To examine the predictive value of both paradigms we performed simultaneous bilateral functional transcranial Doppler ultrasonography on 19 right-handed male native German subjects. The rhyme generation condition produced a significantly stronger lateralization to the supposed hemisphere of language dominance than the classical word generation condition. The observed differences suggest that the rhyme generation paradigm is more robust in detecting hemispheric language dominance than other neuropsychological paradigms and might be most valuable for preoperative assessment of cortical language areas.     

Effects of Dangerous and Competitive Worldviews on Right-Wing Authoritarianism and Social Dominance Orientation over a Five-Month Period

The cross-lagged effects of dangerous and competitive social worldviews on Right-Wing Authoritarianism (RWA) and Social Dominance Orientation (SDO) were examined over a five-month period ( N   =  165). Analyses indicated that the motivational goal for group-based dominance and superiority indexed by SDO changed as a function of the degree to which the social world was perceived as a competitive place characterized by inequality and resource scarcity. The motivational goal for ingroup conformity and collective security indexed by RWA, in contrast, changed as a function of the degree to which the social world was perceived as a dangerous and threatening place prone to high levels of crime and immoral behavior. These findings are consistent with the causal pathways between social worldviews and ideological attitudes predicted by Duckitt's (2001 ) model of the dual motivational and cognitive processes underlying prejudice. An unexpected reciprocal effect in which RWA predicted longitudinal change in dangerous worldview was also identified, suggesting that the relationship between these two constructs may be more complex than previously hypothesized.     

La distribution du voisinage influence l'amorçage orthographique non masqué des mots écrits

The aim of the present research is to study whether orthographic neighbourhood distribution influences unmasked orthographic priming. Two word conditions were compared in the lexical decision task. All word targets had two higher frequency neighbours that were either spread across two letter positions (SINGE/linge-songe) or concentrated on a single letter position (RUCHE/riche-roche). Results showed an inhibitory effect of unmasked orthographic priming. Furthermore, this priming effect was influenced by the target neighbourhood distribution. Priming was only found when the word targets had two neighbours that were spread across two letter positions. These data are discussed within an interactive activation framework in terms of prime activation (Versace and Nevers, 2003).     

儿童早期词汇获得的词类差

儿童早期词汇获得存在词类差异,很多语言中名词比例都要高于其他词类,因此一些研究者提出“名词优势”理论。但是,一些对汉语和韩语的研究发现,儿童早期获得的动词比例与名词没有显著差异,甚至高于名词,同时汉语和韩语动词比例也远大于英语动词比例。针对不同语言儿童早期获得的动、名词比例差异现象,研究者认为语言结构特征和成人对孩子的言语输入可以解释不同语言儿童早期词汇中动、名词比例的差异,其中成人言语中词类的频率、单词位置、词形变化复杂性和语用等因素都会影响儿童早期词汇获得。此外,不同的词汇测量方法、观察情境、词类定义、词汇量水平、单词理解与说出也会造成不同研究结果之间的差异     

事件性前瞻记忆的加工机制：来自ERP的证据

采用事件相关电位技术,对前瞻记忆的加工机制——主要是执行前的加工机制进行研究。控制条件为单纯的背景任务,实验条件为背景任务含前瞻记忆任务,对两种条件下非靶线索的行为数据进行比较,结果表明实验条件下被试的反应时显著长于控制条件,可能说明两种条件的认知过程存在差异,这种差异在ERPs上主要体现为刺激呈现200ms以后,两种条件的波形和脑地形图存在显著差异。结果支持预备注意加工和记忆加工理论,也部分支持多重加工理论     

The day the clock stopped. Primitive states of unintegration,multidimensional working through and the birth of the analytical subject

This paper is based on one idea and built around one clinical experience that helped me to broaden my comprehension of it. The idea, underlying the work of several authors, is that when the analytic field is saturated with primitive and unintegrated mental contents, the analyst’s somatic countertransference is a precious indicator of a deep, dissociated form of communication. The clinical experience concerns the difficult elaboration of a complex, multifaceted countertransference that took place during the early stages of the analysis of a sensitive patient who used to communicate in a very dissociated way and that I found hard to contain. This experience, closely described in the article, led me to formulate the clinical idea that the transference field may be made of distinct layers (psychoid, affective, verbal), and that each one of them may potentially convey dissociated, even contrasting bits of information. The corollary of this is that the analyst should be ready to accept contrasting sensations, feelings and thoughts at the same time, as they might be the basic ingredients of a complex reverie. The analyst could find himself/herself in front of his/her own internal unelaborated multiplicity before a symbolic image may emerge to link the scattered pieces of the experience. Nevertheless, the heart of this paper is not about suggesting an idea, but in the sharing of a complex working through, which fostered the birth of a new, more human relational perspective: the capacity of being together in time, in a transitional space where there is neither total separation nor fusion.     

PTEN、p53和BAG-1在三阴乳腺癌中的表达及意义

为了研究PTEN、p53和BAG-1在三阴乳腺癌中的表达情况及临床病理意义,并讨论三者之间的关系.采用免疫组织化学SP法检测89例三阴乳腺癌中PTEN、p53、BAG-1的表达,其阳性表达率分别为44.9％、47.2％、73.0％,三者的表达均与患者的病理组织学分级、淋巴结转移情况有关(P＜0.05).PTEN的表达与p53、BAG-1表达呈负相关;BAG-1与p53的表达呈正相关,提示三者在三阴乳腺癌中的表达存在一定关联性,临床上联合检测三者可能为TNBC预后评估、患者的个体化治疗提供一定的参考.     

Gradient language dominance affects talker learning

Traditional conceptions of spoken language assume that speech recognition and talker identification are computed separately. Neuropsychological and neuroimaging studies imply some separation between the two faculties, but recent perceptual studies suggest better talker recognition in familiar languages than unfamiliar languages. A familiar-language benefit in talker recognition potentially implies strong ties between the two domains. However, little is known about the nature of this language familiarity effect. The current study investigated the relationship between speech and talker processing by assessing bilingual and monolingual listeners’ ability to learn voices as a function of language familiarity and age of acquisition. Two effects emerged. First, bilinguals learned to recognize talkers in their first language (Korean) more rapidly than they learned to recognize talkers in their second language (English), while English-speaking participants showed the opposite pattern (learning English talkers faster than Korean talkers). Second, bilinguals’ learning rate for talkers in their second language (English) correlated with age of English acquisition. Taken together, these results suggest that language background materially affects talker encoding, implying a tight relationship between speech and talker representations.