应激激素对恐惧消退作用的神经生理机制

恐惧消退是指反复呈现条件刺激（conditioned stimulus, CS）而不匹配无条件刺激（unconditioned stimulus, US）,从而消除个体已有的恐惧反应。应激激素,如去甲肾上腺素（Norepinephrine,NE）和糖皮质激素（Glucocorticoids,GCs）,可通过影响腹内侧前额叶、杏仁核和海马等与消退学习有关的神经回路的活动,调节恐惧消退学习效果。NE和GCs对恐惧消退学习的调节作用受激素水平与激素用药时间的影响,且其调节效果存在性别差异。未来研究需进一步探索应激激素如何影响恐惧消退学习效果,并思考如何利用其影响效果促进暴露疗法疗效。     

Investigation of tensile deformation mechanisms at room temperature in a new Ni-based single crystal superalloy

The deformation microstructures of a new Ni-based single crystal superalloy, M 4706, have been characterized by transmission electron microscopy after interrupted tensile tests at room temperature. It is found that besides shearing of γ′ precipitates by strongly coupled dislocations, another unusual shearing process involving a single a/2 〈1?0?1〉 matrix dislocation as well as the formation of the isolated superlattice stacking fault and Shockley loop also operates actively during initial yielding. Based on experimental observations, occurrence of these different shearing processes is discussed.     

决策信心的认知机制与神经基础

决策信心是指在进行判断或决策时, 个体对其决策最优性或正确性的信心程度。决策信心的单过程理论认为决策与信心评估是并行的同一加工过程; 而决策后理论认为决策和信心评估是串行的两个加工过程。决策信心存在两种典型的偏差效应：过分自信和信心不足。决策信心的神经机制研究指出, 信心评估可能是决策过程中最基本并且普遍存在的一个成分; 对决策信心评估敏感的脑区包括扣带回、背外侧前额叶和顶上小叶等。未来研究应该在决策信心产生的机制、信心与决策如何交互的心理及神经机制等领域展开大量研究。     

内隐记忆中的神经机制研究方法

知觉启动与语义启动神经机制的研究是内隐记忆神经机制研究的两条重要途径。本文介绍了内隐记忆神经机制的研究途径之一：知觉启动神经机制的研究进展情况,并对研究中存在的问题及解决方法提出建议。     

企业高声誉的负面效应的心理学机制

企业高声誉通常被视为企业的无形资产, 可以给企业带来诸多竞争优势。然而, 无论是在常规情景(企业正常经营)下, 还是在危机情景(爆发妨碍企业正常运营并可能伤害企业的事件后)下, 企业高声誉都可能对企业和员工产生负面影响。高声誉的负面效应源于企业声誉的微观心理基础, 即企业利益相关者的认知和情绪。其中, 在常规情景下, 高声誉通过认知和情绪机制分别对企业和员工产生负面效应; 在危机情景下, 高声誉主要通过认知机制恶化危机给企业所带来的负面影响。高声誉的负面效应受到个人、组织和市场等多层次因素的调节, 且常规和危机情景之下负面效应的边界条件有所不同。未来研究可以进一步挖掘高声誉各维度在常规和危机情景下负面影响的独特作用机制和边界条件, 研究各维度之间的交互作用, 拓展高声誉对企业员工的负面影响, 探究高声誉负面影响的动态变化, 以及开展有关高声誉负面效应的元分析。     

音乐句法加工的认知机制与音乐结构的影响模式

音乐和语言是人类最重要的两种交流系统。与语言一样, 音符的排列和组织也是建立在一定的句法规则之上。尽管现有研究发现听众具有感知音乐句法的能力, 音乐句法加工的认知机制以及影响因素仍不清楚。基于此, 拟深入探究预期和整合在音乐音高句法加工中的作用, 以及音乐层级结构和时间结构对音高句法加工的影响。以期进一步揭示音乐句法加工的本质, 为音乐和语言的比较以及探索人类更一般的交流机制提供实证依据。     

心理治疗的过程研究

心理治疗的过程研究是辨识心理治疗的活性成分和改变机制,是心理治疗效果研究的重要领域。心理治疗过程研究的最新进展体现在研究内容的扩展,研究方法的改进及研究结果的新发现等方面。对未来研究的几点建议：活性成分的层次性观点,改变机制的双线研究及与治疗过程模型的结合,借鉴邻近学科的研究成果,改善RCTs时间设计,关注质化研究,临床工作者与研究者的合作,以及开展本土化研究。     

衰老机制的思考

衰老原因和机制极为复杂,是一具有累积性、普遍性、渐进性、内生性和危害性的生命过程。衰老的本质是渐进性的功能减退,各种因素通过引起功能减退加速衰老,减慢功能损害则能延缓衰老。本文笔者认为：衰老机制是非特异性的;理论上,能引起功能减退的因素应能加速衰老。     

Improving mother–child interaction in low‐income Turkish–Dutch families: A study of mechanisms mediating improvements resulting from participating in a home‐based preschool intervention program

This study examined whether the effects on cognitive and language outcomes of a recently developed home‐based educational intervention program, Opstap Opnieuw, for 4–6‐years‐old disadvantaged children could be explained by improved mother–child interaction. The present sample (n=30) was drawn from a larger sample of Turkish–Dutch families (n=181) for which in a previous study significant effects of Opstap Opnieuw were found on children's (first) language and cognitive pre‐math skill, 5 months after the program ended. The present study focused on two facets of interaction quality as possible mediators of these program effects: the mean cognitive distancing level of mothers' communication and instruction behaviour as an indicator of the cognitive and verbal stimulation provided, and the degree of cooperation as an indicator of mothers' social‐emotional support to their children. Both measures were based on systematic observation of mother–child interaction during sorting tasks. Participation in the program appeared to improve mothers' social‐emotional support behaviour substantially, but not their cognitive distancing behaviour. For Turkish (first language) vocabulary, about half of the program effect appeared to be mediated by the improved social‐emotional support. For cognitive pre‐mathematical skills, two‐thirds of the program effect appeared to be mediated by improved social‐emotional support. Mothers' cognitive distancing was moderately‐strongly related to children's vocabulary development, but did not mediate program effects. Some implications of the results are discussed. Copyright © 2004 John Wiley & Sons, Ltd.     

The semantic pointer theory of emotion: Integrating physiology,appraisal, and construction

Emotion theory needs to explain the relationship of language and emotions, and the embodiment of emotions, by specifying the computational mechanisms underlying emotion generation in the brain. We used Chris Eliasmith’s Semantic Pointer Architecture to develop POEM, a computational model that explains numerous important phenomena concerning emotions, including how some stimuli generate immediate emotional reactions, how some emotional reactions depend on cognitive evaluations, how bodily states influence the generation of emotions, how some emotions depend on interactions between physiological inputs and cognitive appraisals, and how some emotional reactions concern syntactically complex representations. We contrast our theory with current alternatives, and discuss some possible applications to individual and social emotions.