Livin在小细胞肺癌中的表达及与Caspase-3相关性研究

为了探讨Livin蛋白在小细胞肺癌（SCLC）组织中的表达及与Caspase-3的关系,我们使用免疫组化法检测Livin和Caspase-3在30例SCLC及癌旁肺组织中的表达。结果显示,Livin在SCLC中表达明显高于正常组织（P〈0．01）,与TNM分期、淋巴结转移和肿瘤大小无关。Caspase-3在SCLC组织中表达明显下降（P〈0．01）,与Livin表达呈负相关。因此,Livin与Caspase-3的异常表达可能在SCLC癌变中起协调作用,并有望成为诊断和基因治疗的新靶点。     

医患文化冲突分析——对医患关系紧张的新审视

医患关系始终表现为一种文化关系,医患关系紧张问题有着复杂的文化根源,当前出现的医患关系紧张问题的实质就是医患之间存在文化冲突。从文化的视角对医患文化冲突的程度、引起冲突的原因以及发生冲突的文化主体进行重新审视,以期进一步认识紧张的医患关系。     

中-英双语者词汇语义通达的大脑功能偏侧化与合作效应

采用半视野速示术对48名英语专业硕士研究生进行词汇判别的语义启动实验,检查中一英双语者词汇语义通达可能存在的大脑功能偏侧化与合作效应.结果提示:(1)相对熟练的中一英双语者L1(中文)和L2(英文)均可直接通达一个共同的词汇语义概念表征系统,但L1可以通过两半球,而L2可能主要依赖于大脑右半球;(2)跨语言条件出现了半球间语义通达的合作优势效应.     

The Monkey as a Psychological Subject

Many species in long-term captivity have tried to kill time by playing friendly games with their warders. In the end, only rhesus monkeys (Macaca mulatta) could tolerate the tedious hide-and-seek games that their human jailers prefer to play. In this article, written many years before the Stockholm syndrome was first described, the author relates how it was eventually discovered which species is most willing to contribute to the development of a genuinely scientific human psychology. Harry F. Harlow died in 1981 and Dr. Frank C.P. van der Horst (fhorst@fsw.leidenuniv.nl) of Leiden University stands as the person to addess correspondence to.

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The role of competition and knowledge in the Ellsberg task

Ambiguity avoidance denotes people's preference for gambling situations with known over unknown, or ambiguous, probability distributions. In four experiments we provide evidence for the interaction between competitiveness and knowledge in Ellsberg's task, in which people have a choice between a risky box (distribution of balls known) and an ambiguous box (distribution of balls not known). If the situation is perceived as competitive (the experimenter or an opponent is responsible for composing the boxes) people avoid ambiguity by betting on the box with the known probability distribution. If the task is perceived as cooperative (a partner or friend is composing the boxes) people are indifferent toward ambiguity or even ambiguity seeking. In addition, we find that people expect their winning odds to be less than even in the ambiguous box. Copyright © 2003 John Wiley & Sons, Ltd.     

The Word's Eternal Silence: A Commentary on Schneider-Harpprecht's Essay

Once the post-modern account of individual and cultural identityas creative openness to change is re-construed in terms of aconstructivist rendering of the semiotic theory of culture,and once interdenominational and inter-faith hospital chaplaincyis interpreted on a model of cross-cultural communication whichagrees with this theory, chaplains can conceive of their abilityto fulfill their mission in offering understanding and helpto the client from other faith communities only by explicitlyinvoking the intervention of the Holy Spirit. The commentaryargues that Schneider-Harpprecht's all too generalized accountof that intervention leaves chaplains with no spiritual substancefor distinguishing between truely and only apparent pastoralhelpfulness.     

Group-based reasons for action

This article endorses a familiar, albeit controversial, argument for the existence of group-based reasons for action, but then rejects two doctrines which other advocates of such reasons usually accept. One such doctrine is the willingness requirement, which says that a group-based reason exists only if (sufficient) other members of the group in question are willing to cooperate. Thus the paper argues that there is sometimes a reason, which derives from the rationality of some group action, to play one's part unilaterally in that group action. This seems implausible only because we tend wrongly to accept a second doctrine, monism about the unit of agency. Monism claims that, for any given deliberative problem, there is only one unit of agency to which reasons attach. If we are monists who believe in group-based reasons, the willingness requirement will seem necessary in order to avoid recklessness. We should reject monism, and if we do so we can recognise genuine conflict between individual-based and group-based reasons, and in doing so we can explain, without endorsing the willingness requirement, why we should not act recklessly.     

医患沟通中患者的信息认知

医患沟通在医疗过程中发挥着重要的作用,沟通中的主要内容是信息交流,信息交流的主要目标是达到医患双方的相互理解.论述影响医患沟通中信息认知的几个因素,其中包括信息的形式,情绪因素,沟通行为因素三个方面.通过对这些因素的干预,提高患者对信息的认知能力将使医患沟通更加有效,从而有利于合作式的医患关系的形成.     

浙江省新型农村合作医疗制度的实践与思考

浙江省农村合作医疗始于20世纪60年代,发展道路曲折,但对解决农民看病问题发挥过巨大的作用.浙江省新型农村合作医疗试点工作于2003年8月启动,新型农村合作医疗具有政府支持力度大、筹资机制较完善、突出大病统筹等与传统合作医疗不同的新特点.但也应该看到,新型农村合作医疗是一项复杂的社会系统工程,实践中会面临许多困难和问题.在建立此项制度的过程中,应加强宣传教育,转变观念,建立相关的法规和制度,完善筹资机制,配套抓好城乡医药卫生体制改革,以保证合作医疗制度的健康发展.     

Infant transfer behavior in humans: A note on the exploitation of young

Human infant transfers filmed in West New Guinea and stored in the archives of Max-Planck Geselschaft are formally described and analyzed relative to reports of similar behavior from nonhuman primates in laboratory and field studies. Motor patterns directed from one individual to another were discriminated and grouped into five categories of behavior ordered according to their relative likelihoods of “damaging aggression” [Fagen, American Naturalist, 115:858–869, 1980]. Transfers generally occurred between two females of different reproductive conditions. Most interactions were directed from the holder of the infant to the infant, demonstrating that the infant is the recipient of most nondamaging as well as potentially damaging behavior. While transfers are characterized by “aggressive restraint,” the least damaging behavior is most likely to precede a transfer and may function to prolong the relative duration of infant holding. Behavior with a relatively high likelihood of damage to the infant by the infant holder is as likely to occur before as after transfer, suggesting that infant transfer behavior in this human society reflects competitive interactions among adult females.