Embryo genetic disorder analysis demonstration project: A model protocol

A demonstration project designed for couples at a minimum 25% risk for having a child with cystic fibrosis is being undertaken using embryo genetic disorder analysis within an organization proficient inin vitro fertilization techniques. Prior to offering the project to patients, issues were identified that needed to be addressed in order to improve the likelihood of success. We then developed a set of protocols that would enable us to introduce this new technology to our staff and to prospective patients in a consistent manner.     

Component analysis with different sets of constraints on different dimensions

Many of the classical multivariate data analysis and multidimensional scaling techniques call for approximations by lower dimensional configurations. A model is proposed, in which different sets of linear constraints are imposed on different dimensions in component analysis and classical multidimensional scaling frameworks. A simple, efficient, and monotonically convergent algorithm is presented for fitting the model to the data by least squares. The basic algorithm is extended to cover across-dimension constraints imposed in addition to the dimensionwise constraints, and to the case of a symmetric data matrix. Examples are given to demonstrate the use of the method.The work reported in this paper has been supported by the Natural Sciences and Engineering Research Council of Canada, grant number A6394, and by the McGill-IBM Cooperative Grant, both granted to the first author. The research of H. A. L. Kiers has been made possible by a fellowship of the Royal Netherlands Academy of Arts and Sciences. We thank Michael Hunter for his helpful comments on earlier drafts of this paper.     

Religion and Science in America: Populism versus Elitism

Historian James Gilbert argues that the dialogue between science and religion is an important dynamic in the creation of contemporary American culture. He traces the dialogue not only in the confines of the academic world but also in popular culture. The science-religion dialogue reveals a basic tension between the material and the spiritual that helps define the core of the American psyche: fascination with material progress yet commitment to traditional religious beliefs. Gilbert's cultural narrative traces the dialogue in a unique way because of the attention given to popular renditions of science and religion in evangelical films used by the military, in televised science programs, in science-fiction literature, and at the Seattle World's Fair in 1962. Gilbert suggests that the discussion between science and religion is significant because it is part of the process of creating new cultural structures necessitated by social, scientific, and technological developments. The tensions between religiously informed commonsense science and professional science work to create new cultural forms in a democratic society. Religion and science in dialogue are part of the process of cultural creation. Dogmatism on the part of either scientists or religionists is countered by the democratic process itself.     

Multitrait Multimethod validation of Implicit Association Test as a measure of individual differences in personality: Is there personality at all?

The objective of the study was to investigate the validity of IAT in the assessment of the Big five personality traits. We employed the Multi-Trait Multi-Method (MTMM) approach on a sample of 146 respondents. We collected measures on IATs assessing Big five personality traits, self-reports, and two ratings of close others of different gender on NEO PI-R. Additionally, we assessed behavior related to the Big five personality traits in a structured interview where three experts independently provided rating measures. MTMM analyses suggest that personality IAT measures have little in common with personality traits measured traditionally using explicit methods. The evidence does not support the claim that personality IAT can serve as a valid measure of individual differences in personality traits.