The Occipital Cortex in the Blind

ABSTRACT— Studying the brains of blind individuals provides a unique opportunity to investigate how the brain changes and adapts in response to afferent (input) and efferent (output) demands. We discuss evidence suggesting that regions of the brain normally associated with the processing of visual information undergo remarkable dynamic change in response to blindness. These neuroplastic changes implicate not only processing carried out by the remaining senses but also higher cognitive functions such as language and memory. A strong emphasis is placed on evidence obtained from advanced neuroimaging techniques that allow researchers to identify areas of human brain activity, as well as from lesion approaches (both reversible and irreversible) to address the functional relevance and role of these activated areas. A possible mechanism and conceptual framework for these physiological and behavioral changes is proposed.     

对人工流产的道德辩护

人工流产的合理性的伦理学辩护基于两个出发点 :已出生人的利益要优于未出生的人 ;人是目的而不是工具。但是 ,这种伦理辩护会带来的某些问题 ,比如 ,过分强调自由与责任的松懈之间的矛盾。对此 ,伦理学对于权利的辩护无法作出回答 ,但它却是人的生存境况所面临的一种两难抉择。     

Consistency in physiological stress responses and electromyographic activity during induced stress exposure in women and men

Physiological responses serve the role as objective indicators of stress as well as a link between psychosocial stress and various health outcomes. The aim of the present exposure session was to compare different physiological stress responses (systolic and diastolic blood pressure, heart rate, urinary epinephrine and norepinephrine, salivary cortisol) as well as trapezius muscle activity, measured by surface electromyography, during mental and physical stress in 11 women and ten men. The results show significantly increased activity in all measures but cortisol and significant associations between sympathetic arousal and EMG activity. The association between sympathetic arousal and muscle activity is of importance for understanding the high prevalence of musculoskeletal disorders in mentally stressful but physically light work tasks. Men had higher blood pressure and a more pronounced increase in epinephrine output than women, whereas women had higher heart rate. It was concluded that sympathetic activity is more sensitive to moderately intense stress exposure than pituitary adrenocortical (cortisol) activity and that men respond to performance stress with more epinephrine output than women. Although the correlations between the different indicators of sympathetic arousal were high, together they could still only explain 30–70% of the inter-individual variance. Thus, several parameters are needed in order to obtain a reliable measure of sympathetic activity.     

On the role of attention in generating explicit awareness of contingent relations: evidence from spatial priming

In a series of four experiments, we examine the hypothesis that selective attention is crucial for the generation of conscious knowledge of contingency information. We investigated this question using a spatial priming task in which participants were required to localize a target letter in a probe display. In Experiment 1, participants kept track of the frequency with which the predictive letter in the prime appeared in various locations. This manipulation had a negligible impact on contingency awareness. Subsequent experiments requiring participants to attend to features (color, location) of the predictive letter increased contingency awareness somewhat, but there remained a large proportion of individuals who remained unaware of the strong contingency. Together the results of our experiments suggest that the construct of attention does not fully capture the processes that lead to contingency awareness, and suggest a critical role for bottom-up feature integration in explicit contingency learning.     

Attentional processes and meditation

Visual attentional processing was examined in adult meditators and non-meditators on behavioral measures of change blindness, concentration, perspective-shifting, selective attention, and sustained inattentional blindness. Results showed that meditators (1) noticed more changes in flickering scenes and noticed them more quickly, (2) counted more accurately in a challenging concentration task, (3) identified a greater number of alternative perspectives in multiple perspectives images, and (4) showed less interference from invalid cues in a visual selective attention task, but (5) did not differ on a measure of sustained inattentional blindness. Together, results show that regular meditation is associated with more accurate, efficient, and flexible visual attentional processing across diverse tasks that have high face validity outside of the laboratory. Furthermore, effects were assessed in a context separate from actual meditation practice, suggesting that meditators’ better visual attention is not just immediate, but extends to contexts separate from meditation practice.     

Subjective discriminability of invisibility: A framework for distinguishing perceptual and attentional failures of awareness

Conscious visual perception can fail in many circumstances. However, little is known about the causes and processes leading to failures of visual awareness. In this study, we introduce a new signal detection measure termed subjective discriminability of invisibility (SDI) that allows one to distinguish between subjective blindness due to reduction of sensory signals or to lack of attentional access to sensory signals. The SDI is computed based upon subjective confidence in reporting the absence of a target (i.e., miss and correct rejection trials). Using this new measure, we found that target misses were subjectively indistinguishable from physical absence when contrast reduction, backward masking and flash suppression were used, whereas confidence was appropriately modulated when dual task, attentional blink and spatial uncertainty methods were employed. These results show that failure of visual perception can be identified as either a result of perceptual or attentional blindness depending on the circumstances under which visual awareness was impaired.     

重复刺激的末位优势效应

探讨在RSVP任务中重复刺激的呈现位置和报告方式对重复知盲效应的影响, 检验该研究提出的注意资源最优化假设和末位优势效应。实验1操作了刺激性质和重复刺激位置, 得出了刺激性质和重复刺激位置的交互效应; 实验2操作了刺激性质和情景信息, 结果是交互效应不显著; 实验3操作了刺激性质和报告方式, 出现了刺激性质和报告方式的交互效应。该结果表明: (1)由于注意资源分配的优化, 重复刺激有末位优势效应。(2)重复知盲的产生不是发生在知觉阶段, 而是发生在报告阶段。(3)注意资源分配最优化理论比建构/归因理论能更合理地解释重复知盲的发生。     

Intentionalism and Change Blindness

According to reductive intentionalism, the phenomenal character of a conscious experience is constituted by the experience's intentional (or representational) content. In this article I attempt to show that a phenomenon in visual perception called change blindness poses a problem for this doctrine. Specifically, I argue that phenomenal character is not sensitive, as it should be if reductive intentionalism is correct, to fine-grained variations in content. The standard anti-intentionalist strategy is to adduce putative cases in which phenomenal character varies despite sameness of content. This paper explores an alternative antiintentionalist tack, arguing, by way of a specific example involving change blindness, that content can vary despite sameness of phenomenal character.

无痛人流不同麻醉的比较

为了更好地实行无痛人流,提高无痛人流的镇痛效果、降低麻醉风险及提高患者满意度,用比较治疗学的理念及方法对目前国内报道的一些主要无痛人流的麻醉方法进行比较和分析。结果发现镇静药丙泊酚与强效镇痛药复合应用于无痛人流安全有效。比较治疗学方法有助于无痛人流不同麻醉的临床抉择。     

The role of perceptual load in inattentional blindness

Perceptual load theory offers a resolution to the long-standing early vs. late selection debate over whether task-irrelevant stimuli are perceived, suggesting that irrelevant perception depends upon the perceptual load of task-relevant processing. However, previous evidence for this theory has relied on RTs and neuroimaging. Here we tested the effects of load on conscious perception using the "inattentional blindness" paradigm. As predicted by load theory, awareness of a task-irrelevant stimulus was significantly reduced by higher perceptual load (with increased numbers of search items, or a harder discrimination vs. detection task). These results demonstrate that conscious perception of task-irrelevant stimuli critically depends upon the level of task-relevant perceptual load rather than intentions or expectations, thus enhancing the resolution to the early vs. late selection debate offered by the perceptual load theory.