The Swedish National Adult Reading Test (NART-SWE): a test of premorbid IQ

The purpose of this study was to construct a Swedish version of the National Adult Reading Test (NART-SWE), a test for assessment of premorbid IQ, and to investigate its validity and reliability on healthy controls and patients with mild Alzheimer's disease. As Swedish pronunciation rules are fixed, NART-SWE was constructed using loan words. NART-SWE has satisfactory psychometric properties: Inter-rater and retest reliability as well as internal consistency are very high. The NART-SWE demonstrates face validity. In addition, high correlation with IQ was obtained. A significant model emerged when using NART-SWE to predict IQ. Furthermore, no significant differences were observed when comparing performance for healthy controls' with that of patients with Alzheimer's disease on NART-SWE. It does appear that reading of irregular words is intact in mild Alzheimer's disease.     

人格分化的智力假设

人格与智力是个体差异中相互关联的两个重要方面,人格随智力水平的提高而不断分化,智力影响了特定人格维度之间的相关。尽管人格分化的智力假设尚未获得一致性的证据,但它却暗示了智力对人格结构的潜在影响。由于人格测量工具的信度和效度可能因受测者的能力水平而异,因此未来的研究应在使用统一测量工具的基础上,尽量扩大被试的能力范围,采用多重评估或集合评定的方法,使人格测量真正独立于受测者的认知能力。     

揭开“看牙难、看牙贵”的面纱

患者对现有分科看牙模式的失望和对牙科医疗机构的商业化模式的疑问,产生了“看牙难、看牙贵”的感叹。通过14年的全科牙医诊疗体系的实践,从结构影响结果的哲学角度提出全科牙医教育培训体系的建立和牙科产业链调整的设想。通过对历史上全科牙医的回顾,推测全科牙医和专科牙医的互补形式,将成为中国牙科医疗体系的“新式样”。通过对牙科医疗机构运行机制的分析提出了改善的建议。     

论医院实行单病种限价的伦理学价值

从单病种限价在医院内部管理机制等方面的作用出发,探讨了实施单病种限价的伦理价值基础和伦理学意义。认为单病种限价政策能促使医院形成“以人为本”的管理理念,切实维护患者利益,培养医务人员的医德素质,促使医院重视德源资产和品牌形象的建设,强化医务人员精益求精的科学精神,取信于民并帮助医院树立诚信的道德形象,是医院可持续发展的可取途径。     

框架效应及其认知机制的研究进展

框架效应违背了不变性原则,是描述性决策理论违背规范性理论的经典异像。以亚洲疾病问题为代表的经典框架效应又称作风险选择框架效应,此外还包括特征框架效应等不同类别。框架效应受损益值类型和大小等社会线索影响。除展望理论可以解释其认知机制外,模糊痕迹理论和概率心理模型等也对此加以解释。框架效应的脑机制在大脑右半球和杏仁核等区域。文章最后对全文做了总结及展望。     

The Psychosocial Vulnerability Model of Hostility as a Predictor of Coronary Heart Disease in Low-income African Americans

The current study examined social support and stress as mediators of the hostility—coronary heart disease (CHD) relationship as suggested by the psychosocial vulnerability model in a sample of low-income African Americans. Among 95 CHD patients and 30 healthy controls, hostility was negatively correlated with social support, but was not related to minor stress. CHD patients endorsed higher levels of hostility; however, the relationship between hostility and CHD status was diminished once stress and social support were included in the model. This study lends partial support for the psychosocial vulnerability model of hostility in African Americans, but suggests that the relationship between hostility and stress may be impacted by socioeconomic status.     

Rigidity in social and emotional memory in the R6/2 mouse model of Huntington's disease

Four experiments were conducted to examine social and emotional memory in the R6/2 transgenic mouse model of Huntington’s disease. First, R6/2 mice were tested in a social transmission of food preference task where they had to acquire a preference for a flavoured food (acquisition) and subsequently to learn a preference for a different flavour (shifted reinforcement). R6/2 mice performed well in the acquisition trial. However, they were impaired in the shifted reinforcement trial and perseverated on the first preference learned. Second, mice were trained in an inhibitory avoidance paradigm, with either one or two footshocks delivered during the training. WT mice given one footshock showed retention levels lower than those of mice trained with two footshocks. By contrast, there was no difference in retention levels of R6/2 mice given either one or two footshocks. Third, mice were tested in an active avoidance task that paired a mild footshock with a warning light. R6/2 mice had a strong age-dependent deficit in this task. Finally, mice were tested in a conditioned taste aversion task that paired a saccharine solution with a nausea-inducing agent (LiCl). R6/2 mice displayed normal aversion, however this was not extinguished following repeated exposure to saccharine solution alone. Our data show that while R6/2 mice have functional hippocampus-based memory, they have deficits in striatum-based memory skills. Further, social and emotional memories appear to be encoded in a rigid way that is not influenced by subsequent learning or by arousal levels.     

出血性脑血管病介入治疗进展

出血性脑血管病的介入栓塞治疗由于血管内辅助技术与各种栓塞材料的综合应用取得快速发展,主要有以下三个方面：（1）生物修饰弹簧圈、封堵球囊和支架技术的应用使复杂颅内动脉瘤的介入治疗成为可能;（2）非粘附性液体栓塞剂的应用提高了脑动静脉畸形和硬脑膜动静脉瘘的单纯栓塞治愈率;（3）带膜支架在颅底部巨大动脉瘤和创伤性动静脉瘘取得开创性应用。     

超声心动图与心血管造影X线引导下先心病介入封堵治疗的比较

目前先天性心脏病介入治疗已成为介入心脏病学的新热点,而先心病介入治疗离不开影像学引导,目前临床上常用的影像学引导方式主要有超声心动图和心血管造影两种,本文针对两者优缺点,从治疗方式、疗效、费用等方面进行比较,为临床治疗思路提供借鉴。     

古埃及疾病医治理念透析

疾病医治理念是古埃及文明的重要组成部分。古埃及人针对不同类别疾病有着相应的医治理念：药物、魔法与意志是内科疾病的医治理念;河渠原理是医治外科疾病的理念;对于治疗心理疾病主要是寻求神灵的拯救;预防疾病的理念是保持圣洁。挖掘、梳理这些医治理念,可以加强医学史的学科建设,对某些疾病的治疗有参考价值。