The Neuropsychology of Amphetamine and Opiate Dependence: Implications for Treatment

Chronic use of amphetamines and/or opiates has been associated with a wide range of cognitive deficits, involving domains of attention, inhibitory control, planning, decision-making, learning and memory. Although both amphetamine and opiate users show marked impairment in various aspects of cognitive function, the impairment profile is distinctly different according to the substance of abuse. In light of evidence showing that cognitive impairment in drug users has a negative impact on treatment engagement and efficacy, we review substance-specific deficits on executive and memory function, and discuss possibilities to address these during treatment intervention.     

不同年级学生抑制控制研究

从小学三年级、五年级、初中二年级、高中二年级中,挑选被试各80人,进行抑制控制测量。结果发现：（1）抑制控制力的发展随着年级的增长而发展。（2）各年级学生的两项抑制控制测试成绩与语文、数学成绩有较高的正或负相关。结论：抑制控制力与学生的学业成绩关系密切,即抑制控制是有效学习的监控系统。     

Cues that trigger social transmission of disinhibition in young children

Previous studies have shown that observing a human model’s actions, but not a robot’s actions, could induce young children’s perseverative behaviors and suggested that children’s sociocognitive abilities can lead to perseverative errors (“social transmission of disinhibition”). This study investigated how the social transmission of disinhibition would occur. Specifically, the authors examined whether a robot with human appearance (an android) triggered young children’s perseveration and compared the effects of the android with those of a human model. The results revealed that the android induced the social transmission of disinhibition. Also, children were more likely to be affected by the human model than by the android. The results suggested that behavioral cues (biological movement) may be important for the social transmission of disinhibition.     

丙种球蛋白治疗成人重症心肌炎的临床观察

观察丙种球蛋白对成人重症心肌炎的治疗效果及对预后的影响。回顾性分析该院自2009年1月至2010年10月治疗的成人急性重症心肌炎33例,分为丙种球蛋白组（丙球组）及常规治疗组（对照组）。丙种球蛋白组给予患者丙球2g／kg,2天～3天内静脉滴入,同时给予常规治疗;对照组患者给予常规治疗。结果治疗后丙球组优于对照组（P〈0...     

幼儿自我调节能力的发展及与气质的关系

本研究主要讨论幼儿自我调节能力的发展及与气质的关系。研究从执行功能的角度入手,采用实验法和问卷法对90名3～5岁的幼儿进行研究,通过创设难度递进的冲突情境来考察儿童在两种不一致规则中的转换能力。结果表明,幼儿自我调节能力的发展随年龄增长而提高,并存在显著的年龄差异;幼儿气质与自我调节能力的发展有着密切的关系,特别是专注性和社会抑制性维度对不同水平的幼儿自我调节能力的方差检验都达到了显著,二者与年龄一起,能够对幼儿自我调节能力进行一定程度的预测。     

A mechanism for reducing delay discounting by altering temporal attention

Rewards that are not immediately available are discounted compared to rewards that are immediately available. The more a person discounts a delayed reward, the more likely that person is to have a range of behavioral problems, including clinical disorders. This latter observation has motivated the search for interventions that reduce discounting. One surprisingly simple method to reduce discounting is an "explicit-zero" reframing that states default or null outcomes. Reframing a classical discounting choice as "something now but nothing later" versus "nothing now but more later" decreases discount rates. However, it is not clear how this "explicit-zero" framing intervention works. The present studies delineate and test two possible mechanisms to explain the phenomenon. One mechanism proposes that the explicit-zero framing creates the impression of an improving sequence, thereby enhancing the present value of the delayed reward. A second possible mechanism posits an increase in attention allocation to temporally distant reward representations. In four experiments, we distinguish between these two hypothesized mechanisms and conclude that the temporal attention hypothesis is superior for explaining our results. We propose a model of temporal attention whereby framing affects intertemporal preferences by modifying present bias.     

A Measure of Delay Discounting Within the Academic Domain

It is important to better understand the decision‐making processes involved in student procrastination, in order to develop interventions that reduce this common problem. Students may procrastinate because studying produces delayed reinforcers; however, no task measuring delay discounting of academic outcomes currently exists. In Experiment 1, we developed and piloted a measure of academic discounting modeled on titrating‐amount tasks successfully used in the discounting literature. Participants made hypothetical choices between working for money (the smaller, sooner reinforcer) and working on an assignment that was due at various times (the larger, later reinforcer). Participants showed systematic decreases in the subjective value of the assignment as a function of delay, and the hyperbolic and hyperboloid models described the shape of this decrease in value well. In general, larger delayed rewards are discounted less steeply than smaller delayed rewards (the magnitude effect). In Experiment 2, we observed the magnitude effect in academic discounting: Participants discounted a “not important” assignment more steeply than an “important” assignment. In the hyperboloid model, this change was captured by an increase in the s parameter. Results provide support for the validity of the academic discounting task. Copyright © 2018 John Wiley & Sons, Ltd.     

Development of norms for executive functions in typically-developing Indian urban preschool children and its association with nutritional status

Executive functions (EFs) are essential and important for achieving success in children’s everyday lives and play a fundamental role in children’s cognitive, academic, social, emotional and behavioral functioning. A cross-sectional study was carried out to develop age- and sex-specific norms for EFs using the Behavior Rating Inventory of Executive Function – Preschool Version (BRIEF-P) among 2- to 5-year-olds from urban Bangalore, India. In addition, the association between EFs and anthropometric measures, a marker of nutritional status, is also examined. Primary caregivers of 412 children, equally distributed by age and sex, participated. Raw scores for each domain and indices were converted to standard t-scores and percentiles were computed. A t-score at or above 63 corresponding to the 90th percentile was considered as the cutoff for executive dysfunction in this sample. The prevalence of executive dysfunction is 10% based on the Global Executive Composite score of the BRIEF-P. The cutoff score for identifying executive dysfunction using existing United States (US) norms is higher compared to the cutoff score obtained in the current study. Therefore, using US norms for Indian children could result in the prevalence of executive dysfunction been underestimated. Multiple linear regression analysis revealed that stunted and underweight children have significantly elevated EF scores after adjusting for age, sex and socioeconomic status (SES; p < .01). A greater understanding of EFs in preschool children is important for the early identification of executive dysfunction and implementing interventions to improve their future prospects. This study also shows that undernourished children are more likely to have executive dysfunction.     

Gambling and Delay Discounting in Japanese Students

The present study examined the relationship between gambling behavior and delay discounting with Japanese residents. Japanese university students were selected into pathological gambler and non‐gambling control groups using a Japanese version of the South Oaks Gambling Screen. In a discounting task, participants chose individually between a large delayed reward and a smaller immediate reward with varied delays. The discounting rate (k‐value) and the area under the curve were significantly higher and smaller, respectively, for the gambler group than for the control group. These findings show that Japanese gamblers discount delayed rewards more steeply than non‐gambling controls, as has been found in U.S. residents.     

语音记忆和中央执行功能在不同年级儿童解码和语言理解中的作用

选取256名三～六年级儿童,采用相关分析、结构方程模型等方法考察了语音记忆和中央执行功能在不同年级儿童的解码和语言理解中的作用。结果显示,在低年级阶段,语音记忆和刷新对解码存在显著预测作用,转换和刷新对语言理解存在显著预测作用;在高年级阶段,只有刷新对解码保持着稳定的预测作用。这表明,语音记忆和中央执行功能对儿童的解码和语言理解存在不同的影响,并且这种影响会随着年级的增长发生变化。