概率贴现和时间贴现在人脑中的分离

本研究运用ERP技术来检验概率贴现和时间贴现是否反映了相同的神经机制过程。在本研究中,我们在一个刺激中同时操纵概率贴现（风险vs.安全）和时间贴现（1个月后vs.今天）水平。通过对两个过程上的ERN以及全时间段的ERP分析来确定它们是否反映了相同的认知过程。结果发现,这两者在ERN上存在差异,同时这两个效应在ERP的时程和出现的电极点上都存在差异。这些差异表明这两者可能包含着不同的神经机制过程。     

双视角下编码与提取相关性词差异的ERP研究

当个体的特征对周围人的利害影响大于本人时（如残忍）,该特征是他相关（other-relevance）的;反之则是主相关（possessor-relevance,如忧郁）的。研究比较了两种视角下（接受者视角：加工他人的特征;持有者视角：加工自我的特征）相关性特征在编码（判断特征词的相关性）与提取（新旧判断）过程中的ERP特点并发现：编码时双视角下都有他相关比主相关的波幅更大;提取时双视角下都有他相关比主相关的N400波形更负,仅在持有者视角时主相关比他相关的P600更正。可见他相关的加工优势体现在双视角下编码的全程与提取的早期,而主相关的优势表现在持有者视角的情景记忆提取过程中。     

白血病诱导分化治疗中的生态自然观

诱导分化是一种治疗白血病的新方法,它通过促使分化不完全的肿瘤细胞分化成熟,使恶性转为良性.临床应用全反式维甲酸(ATRA)和三氧化二砷(As2O3)诱导急性早幼粒细胞性白血病取得了较高的完全缓解率,毒副作用也较低.诱导分化治疗策略突破了将杀灭肿瘤细胞作为治疗肿瘤的惟一方法的思维局限,谋求在与白血病细胞的和谐中获得人类的健康,是生态自然观应用于医疗实践的成功范例.     

Stress, Coping, and Differentiation of Self: A Test of Bowen Theory

Differentiation of self from the family of origin is thought to be a significant factor in psychological functioning. Bowen contended that the effects of stress are moderated by differentiation of self, such that high levels of stress would have more impact on individuals lower in differentiation as compared to individuals higher in differentiation in predicting dysfunction. We tested this hypothesis and also assessed the relations among stress, coping, differentiation of self, and dysfunction. Results provided support for Bowen's prediction; differentiation indeed moderated the effects of perceived stress in predicting psychological functioning in expected ways. The interaction of differentiation of self and stress predicted variance in functioning beyond what was accounted for by coping styles, suggesting that although coping and differentiation of self are related, they are not synonymous.     

Age-related differentiation of cognitive abilities in ages 3–7

One important issue in the study of individual differences in cognitive abilities has been the question whether abilities tend to become more differentiated with increasing age. The present study examines age-related differentiation in the structure of cognitive abilities among children 3–7 years of age, using data from the recently undertaken Swedish standardisation of the Wechsler Preschool and Primary Scale of Intelligence-Revised. A confirmatory factor analytic modelling approach is applied. Models of different factor structure are built, evaluated and tested against empirical data using the LISREL 8 and the Mplus2 programs run under the STREAMS modelling environment. The results provide support for the notion that cognitive abilities show increasing differentiation with increasing age.     

ERP研究反映感数与计数的不同脑机制

对于较小数目的快速准确认知的“感数”现象一直是一个引人兴趣的问题,这一感数过程到底本质是什么,它与计数过程究竟是同一种加工还是分属两种不同类别,对于这个问题多年来一直存在着争论。本实验的目的在于研究感数加工的本质,运用ERP手段来探索其与计数的不同机制;并且以分心物变量为指标,研究在有分心物呈现时,感数与计数过程将会有哪些变化以及其潜在的神经机制。对14名正常青年人记录感数与计数加工过程中的事件相关脑电位（ERP）。刺激图片由位于屏幕中心的靶(白色矩形)或者靶+分心物(白色圆形)组成,靶的数目分为感数（1－3个靶）及计数（4－6）;而分心物的数目有三种水平：零（无分心物）,与靶的数目相同及两倍于靶的数目。被试计算图片上白色矩形的个数并对所得数目进行奇偶判断,最后根据奇偶性用左右手进行按键反应。行为结果表明,感数与计数的反应时在靶数目之间有显著性差异,靶数目相同时,分心物越多,则被试所需要的反应时就越长。ERP测量表明P1波幅随着靶数目的增加而增大,随着分心物数目的增加而增加;N1波潜伏期随着靶数目的增加和分心物数目增加而减小,N1波幅随着靶数目和分心物的增加而增加;P3波幅随着靶数目的增加而减小,在某些记录点具有靶效应和干扰效应。研究结果提示感数加工具有明显的分心物效应,而计数加工则不然,支持感数与计数分属两种不同功能加工过程的观点,感数加工更易受到分心物出现的干扰。     

From rat sexual behavior to schizophrenia: a tribute to Professor Emeritus Knut Larsson

In July of 2002 Knut Larsson celebrated his 80th birthday. He could by then have looked back at a long and distingusihed career in the field of biological psychology. His research on sexual behavior had contributed to a basic understanding of many behavioral, endocrine and neural phenomena associated with or underlying sexual activity. Instead of looking back at his past achievements, Knut has preferred to look forward, constantly trying to find ways to stimulate interest in his own field and in biological psychology in general. This issue is a humble contribution to the noble end of enhancing the standing of biological psychology, particularly in Scandinavia. Foremost, however, it is a homage to a man of outstanding vision and intellectual integrity: Knut Larsson.     

Dynamic integration: affect, cognition, and the self in adulthood

Positive self- and emotional development is often measured by optimization of happiness, but a second aspect of positive development—the ability to tolerate tension and negativity in the interest of maintaining objective representations—needs to be integrated with this hedonic emphasis. The integration of these two aspects, optimization and differentiation, reflects a dynamic balance. Such integration is possible when emotional activation or arousal is moderate, but is impaired at very high levels of activation. From youth to middle adulthood, the capacity for integration increases, but later in life, limitations or poor regulation strategies foster compensatory processes that compromise integration.     

Cognitive fusion and emotion differentiation: does getting entangled with our thoughts dysregulate the generation,experience and regulation of emotion?

We tested whether cognitive fusion impairs emotion differentiation and thereby mediates relations between cognitive fusion and depression and panic symptoms among 55 adults (M_age?=?26.8 (3.9), 50.9% women). Using visual stimuli, we elicited multiple emotion states and measured (a) emotional intensity – the subjective emotion intensity of elicited emotions (i.e. Specific Emotion Intensity – SEI), as well as (b) emotional differentiation – the degree of co-activation of multiple negative emotions when a specific emotion was elicited (i.e. Multiple Emotion Co-Activation – MECA). First, as hypothesised, we found that cognitive fusion predicted lower levels of emotion differentiation (MECA). In contrast, as hypothesised, these effects were significantly greater than the (null) effects of cognitive fusion on emotion intensity (SEI). Second, as predicted, MECA, but not SEI, predicted depression and panic symptoms. Finally, we found that MECA mediated the effects of cognitive fusion on depression and panic symptoms. The present findings contribute novel, preliminary empirical insight into associations between cognitive fusion, impaired emotion differentiation and mental ill-health.     

网球运动专长对深度运动知觉影响的ERP研究

结合专家-新手范式与ERP技术,研究网球运动专长对个体深度运动知觉产生的影响。通过记录网球专家和新手各19名进行深度运动模式判断时的行为和ERP数据,比较两组个体深度运动知觉的行为反应差异和脑电特征。结果显示,网球专家组深度运动知觉的判断准确率高于新手组;新手组在球体靠近时P1(PO7点)的潜伏期比球体远离时的潜伏期长,专家组无显著性差异;专家组在球体靠近时的P2(Oz点)成分潜伏期长于球体远离时的潜伏期。结果表明,网球运动专家的深度运动知觉能力在准确性上较新手高;运动专长效应与选择性注意资源的调用以及模式识别有关;枕区P2成分可作为深度运动知觉的评价指标。