孤独症儿童动作发展障碍的神经机制

动作发展障碍(Developmental motor disorders)是孤独症谱系障碍的常见特征。通过系统回顾孤独症儿童动作发展障碍的神经科学研究, 发现γ-氨基丁酸和5-羟色胺浓度的改变及γ-氨基丁酸相关蛋白和Shank蛋白的表达异常不仅会损害中枢神经系统的发育, 而且还能导致突触兴奋性与抑制性失衡, 进而改变孤独症儿童小脑和大脑皮层运动区的功能连接。孤独症儿童小脑、基底神经节和胼胝体结构的改变对全脑的连通性产生了负面影响。神经生化机制和脑结构的异常共同导致了脑功能的异常, 最终造成孤独症儿童的动作发展障碍。此外, 动作发展障碍与孤独症核心症状共同的神经基础主要包括镜像神经元系统紊乱, 丘脑、基底神经节和小脑异常以及SLC7A5和PTEN 基因突变。未来研究需要关注与运动密切相关的其他神经递质, 如乙酰胆碱和多巴胺; 探索动作发展障碍神经网络的动态机制及其形成; 剖析该障碍的神经机制和自闭症核心症状神经机制的相互作用。     

Action representation deficits in adolescents with developmental dyslexia

Developmental dyslexia (DD), a severe and frequent disorder of reading acquisition, is characterized by a diversity of cognitive and motor deficits whose interactions still remain under debate. Although deficits in the automatization of sensorimotor control have been highlighted, internal action representation allowing prediction has never before been investigated. In this study, we considered action representation of 18 adolescents with pure DD and 18 age-matched typical readers. Participants actually and mentally performed a visually guided pointing task involving strong spatiotemporal constraints (speed/accuracy trade-off paradigm). While actual and mental movement times of typical readers were isochronous and both conformed to Fitts’ law, the movement times of dyslexics differed between conditions, and only the actual movement times conformed to Fitts’ law. Furthermore, the quality of motor imagery correlated with word reading abilities. This suggests that the process of action representation is impaired in pure DD and supports the sensorimotor perspective of DD. Theoretical implications are discussed.     

Behavioural deficiencies of aggressive 8–9 year old boys: An observational study

The nature of aggressive boys' behaviour is examined. Pre-selected matched pairs of aggressive and control boys were observed in a naturalistic setting which facilitated comparison of the way in which recorded behaviours affected their respective peer relationships. A continuous commentary describing the child's interactions with others was recorded simultaneously with the child's speech during school play. These data were transcribed and coded according to activity, social participation, neighbours, and interactions. Individual behavioural items were grouped on the basis of their functional similarity. Marked differences were found between the two groups on certain categories, giving a clear indication of specific deficiencies in the behavioural repertoire of the aggressive boys.     

Individual differences in the study of human aggression

Excessive concern for simplicity has often led us to underestimate the complexity of aggression. Over the years, several scales related to aggression have been identified and validated both on adults and on children. Ultimately, two main higher order dimensions, emotional responsivity and proneness to aggression, repeatedly emerged in a series of second-order factor analysis. These dimensions are rather similar to two of the big five factors of personality: neuroticism/emotinal stability and hostility/agreeableness, respectively. Several studies corroborate the plausibility of a higher level bidimensional conceptualization of aggression that, while preserving the heuristic validity of looking for more specific constructs of aggression, can link the field of aggression to the field of personality. © 1994 Wiley-Liss, Inc.     

Explaining the Asian American Youth Paradox: Universal Factors versus Asian American Family Process Among Filipino and Korean American Youth

This study used longitudinal survey data of Filipino American and Korean American youth to examine ways in which universal factors (e.g., peer antisocial behaviors and parent–child conflict) and Asian American (AA) family process variables (e.g., gendered norms) independently and collectively predict grade point average (GPA), externalizing, and internalizing problems. We aimed to explain the “Asian American youth paradox” in which low externalizing problems and high GPA coexist with high internalizing problems. We found that universal factors were extensively predictive of youth problems and remained robust when AA family process was accounted for. AA family process also independently explained youth development and, in part, the AA youth paradox. For example, gendered norms increased mental distress. Academic controls did the opposite of what it is intended, that is, had a negative impact on GPA as well as other developmental domains. Family obligation, assessed by family-centered activities and helping out, was beneficial to both externalizing and internalizing youth outcomes. Parental implicit affection, one of the distinct traits of AA parenting, was beneficial, particularly for GPA. This study provided important empirical evidence that can guide cross-cultural parenting and meaningfully inform intervention programs for AA youth.     

The unfolding dark side: Age trends in dark personality features

Age and gender differences across the lifespan in dark personality features could provide hints regarding these features’ functions. We measured manipulation, callous affect, and egocentricity using the Dirty Dozen and their links with agreeableness in a pooled cross-sectional dataset (N = 4292) and a longitudinal dataset (N = 325). Age trends for all dark personality features were progressive through adolescence, but negative through adulthood. Men scored higher than women, but the gender gap varied with age. Trends for agreeableness partly mirrored these trends and changes in dark personality features and agreeableness were correlated. Results are discussed in light of the maturity principle of personality, gender role socialization processes, and issues regarding incremental validity of dark personality over traditional antagonism measures.     

Stroop interference is a composite phenomenon: Evidence from distinct developmental trajectories of its components

Only one previous developmental study of Stroop task performance (Schiller, 1966) has controlled for differences in processing speed that exist both within and between age groups. Therefore, the question of whether the early developmental change in the magnitude of Stroop interference actually persists after controlling for processing speed needs further investigation; work that is further motivated by the possibility that any remaining differences would be caused by process(es) other than processing speed. Analysis of data from two experiments revealed that, even after controlling for processing speed using z‐transformed reaction times, early developmental change persists such that the magnitude of overall Stroop interference is larger in 3rd‐ and 5th graders as compared to 1st graders. This pattern indicates that the magnitude of overall Stroop interference peaks after 2 or 3 years of reading practice (Schadler & Thissen, 1981). Furthermore, this peak is shown to be due to distinct components of Stroop interference (resulting from specific conflicts) progressively falling into place. Experiment 2 revealed that the change in the magnitude of Stroop interference specifically results from joint contributions of task, semantic and response conflicts in 3rd‐ and 5th graders as compared to a sole contribution of task conflict in 1st graders. The specific developmental trajectories of different conflicts presented in the present work provide unique evidence for multiple loci of Stroop interference in the processing stream (respectively task, semantic and response conflict) as opposed to a single (i.e. response) locus predicted by historically – favored response competition accounts.     

A comparison of multiple reinforcer assessments to identify the function of maladaptive behavior

Functional analysis results indicated that maladaptive behaviors displayed by a 25-year-old man with profound mental retardation were maintained by attention from caregivers and possibly, to a lesser degree, by access to tangible items. A concurrent-schedules procedure was then used to study the relative reinforcing value for maladaptive behavior of attention versus tangible items. Results of the concurrent-schedules assessment and subsequent functional communication training indicated that preference for attention versus access to a tangible object varied.     

An evaluation of simultaneous and sequential presentation of preferred and nonpreferred food to treat food selectivity

In the current investigation, we compared two methods of food presentation (simultaneous vs. sequential) to increase consumption of nonpreferred food for 3 children with food selectivity. In the simultaneous condition, preferred foods were presented at the same time as nonpreferred food (e.g., a piece of broccoli was presented on a chip). In the sequential condition, acceptance of the nonpreferred food resulted in presentation of the preferred food. Increases in consumption occurred immediately during the simultaneous condition for 2 of the 3 participants. For 1 participant, increases in consumption occurred in the simultaneous condition relative to the sequential condition, but only after physical guidance and re-presentation were added to treatment. Finally, consumption increased for 1 participant in the sequential condition, but only after several sessions. These results are discussed in terms of possible mechanisms that may alter preferences for food (i.e., establishing operations, flavor-flavor conditioning).