某院3年医院感染患者细菌分离及耐药性分析

应用WHONET5．3软件对2005年1月至2007年12月检出的1749株病原菌种类、分布及其耐药性进行统计分析。结果发现院内感染病原菌以条件致病菌为主,革兰阴性菌检出率61．8％,革兰阳性菌的检出率33％,真菌检出率为5．2％。大肠埃希菌及肺炎克雷伯菌属的ESBLs阳性率分别为34．4％和48．9％,MRSA和MRCNS的检出率分别为40．8％和36．4％。大多数病原菌对抗生素产生多重耐药性。由此可见,由于临床抗生素的广泛使用,病原菌不断变迁且其耐药性逐渐上升,应加强耐药性监测及合理使用抗生素,以有效控制细菌感染和耐药性播散。     

Image Manipulation as Research Misconduct

A growing number of research misconduct cases handled by the Office of Research Integrity involve image manipulations. Manipulations may include simple image enhancements, misrepresenting an image as something different from what it is, and altering specific features of an image. Through a study of specific cases, the misconduct findings associated with image manipulation, detection methods and those likely to identify such manipulations, are discussed. This article explores sanctions imposed against guilty researchers and the factors that resulted in no misconduct finding although relevant images clearly were flawed. Although new detection tools are available for universities and journals to detect questionable images, this article explores why these tools have not been embraced.

线索靶子关联和搜索策略对注意捕获的作用

采用线索化范式, 通过实验任务设计线索与靶子不同的关联并鼓励被试采用不同的搜索策略, 探讨线索与靶子间的知觉关联、语义关联及特征独子检测模式、特征搜索模式对注意捕获的作用。通过线索无效条件和线索有效条件反应时之差判断每一条件下的捕获量, 并综合各条件的反应情况做出结论如下：(1)线索与靶子的知觉关联调控注意捕获, 其效应不受语义关联和搜索策略影响; (2)线索与靶子的语义关联只在排除知觉关联后调控注意捕获; (3)控制知觉关联和语义关联后, 特征搜索模式不影响注意捕获, 而特征独子检测模式对注意捕获有影响。这表明语义知识和知觉经验根据当前任务要求共同作用指导个体的视觉加工, 表现了人类加工系统的灵活性和可调节性。     

Should metacognition be measured by logistic regression?

Are logistic regression slopes suitable to quantify metacognitive sensitivity, i.e. the efficiency with which subjective reports differentiate between correct and incorrect task responses? We analytically show that logistic regression slopes are independent from rating criteria in one specific model of metacognition, which assumes (i) that rating decisions are based on sensory evidence generated independently of the sensory evidence used for primary task responses and (ii) that the distributions of evidence are logistic. Given a hierarchical model of metacognition, logistic regression slopes depend on rating criteria. According to all considered models, regression slopes depend on the primary task criterion. A reanalysis of previous data revealed that massive numbers of trials are required to distinguish between hierarchical and independent models with tolerable accuracy. It is argued that researchers who wish to use logistic regression as measure of metacognitive sensitivity need to control the primary task criterion and rating criteria.     

Bridging novelty and familiarity-based recognition memory: A matter of timing

Novelty detection is essential to adapt to changes. However, the relationship between novelty detection and visual recognition memory remains unclear. To characterize the temporal dynamics of novelty and its connection to familiarity, we probed early behavioural performance of novelty and familiarity in 31 participants using a speeded go/no-go recognition task with a 600-ms response deadline. Responses to familiarity and novelty produced symmetrical biases and correlated accuracies and biases, but novelty decisions were less accurate and had slower minimal reaction times (410?ms). These processes thus appear to be independent, as suggested by a more efficient system in the case of familiarity, but with common factors bringing overlapping contributions to both processes. This may possibly be explained by the more fluent processing of repeated stimuli, but with familiarity and novelty potentially relying on one decision criterion, as suggested by the correlated and remarkably symmetrical biases. This study supports models that conceptualize novelty and familiarity decisions as two partly overlapping processes.     

The analyst's narrative function: Inventing a possibility

This article describes a psychic function common to analysts that was gradually revealed through clinical work with children. It is a psychic quality derived from function α, which involves analysts’ capacity for reverie – their narrative function. The author presents two clinical situations where this function developed in the analytic field in relation to patients’ difficulty in symbolizing. In the first case there was an early traumatic experience unavailable for representation. The analyst lent the patient her ability to represent and produced a narrative that made it possible to create a world of phantasies and transform nightmares into ‘dreamable’ dreams. In other words, she removed the quality of unbearable, irrepresentable reality that characterized those raw experiences encrypted in the psyche. In the second case the analyst's narrative function sought to connect with the isolation, the shell that housed a child suffering from an autistic disorder whose ability to represent had not been established. The analyst provided meaning for the patient's repetitive, stereotyped play, thus weaving the child's subjectivity and gradually introducing a notion of alterity. The author seeks to show how this function, in the thematic construction of the session, facilitated both the working‐through of a traumatic situation (with the ability to share representations) and the constitution of the psychic fabric.     

Putting down roots: the significance of technical adaptations in the therapeutic process with fostered and adopted children‡

Severely neglected and traumatised children have also suffered from a lack of the parental nurturing which is needed for ordinary emotional development to take place. Often their past experiences make them unable to utilise the nurturing that foster and adoptive families try to give them and they are delayed or stuck in their development. In therapy, when the early small signs of new emotional development start to emerge, they may be heralded by technical challenges to the therapist. Two examples are given in this paper, which are discussed in the context of Stern et al.’s ideas about moments of meeting, Winnicott’s concepts about transitional phenomena and playing, and Hurry and her colleagues’ thoughts about the therapist as a developmental object. It is argued that it is important for the therapist to be alert to the possible significance of these technical adaptations in terms of the child’s capacity for new emotional development. These often indicate that a watershed in the treatment has been reached and if positively responded to, that the patient is in the process of ‘putting down roots’ in the ground of the therapeutic relationship and starting to grow across a spectrum of developmental pathways.     

Studying Stereotype Accuracy from an Integrative Social‐Personality Perspective

This article proposes an integrative framework for understanding the accuracy and inaccuracy of stereotypes. Specifically, we highlight research issues and traditions from social and personality psychology that do not often intersect, but which can be mutually informative. Within this framework, the social psychologist's interest in the accuracy of group stereotypes is conceptually much like a personality psychologist's interest in the accuracy with which perceivers can identify types of individuals, for example extraverts. Both fields make use, implicitly or explicitly, of personal attributes and behaviors (cues) in assessing accuracy of beliefs about group or individual traits. By using Brunswik's lens model perspective in combination with concepts from signal detection theory, judgments of stereotypes can be discovered to be accurate or inaccurate depending on how perceivers judge or use the cues. In drawing on research traditions and theoretical frameworks from both social and personality psychology, researchers can go beyond an all‐or‐nothing stance regarding stereotype accuracy to achieve a more nuanced understanding of when, how, and to what extent stereotypes are accurate.     

Inducing lucid dreams by olfactory-cued reactivation of reality testing during early-morning sleep: A proof of concept

The reliable induction of lucid dreams is a challenge in lucid dream research. In a previous study by our research group we were able to induce in about 50% of the participants a lucid dream in a single sleep laboratory night by combining a wake-up-back-to-bed sleep protocol and a mnemonic technique. In the present study, we extended our previous procedure by additional presentation of an odor during sleep to reactivate memory traces about reality testing. In total 16 male participants spent a single night in the sleep lab whereas the procedure induced in two participants a lucid dream (12.5%). The induction rate stays below the success rate of our previous study and therefore odor-cueing seems not a promising technique for inducing lucid dreams. Beside the odor presentation, several other methodological changes have been made, which will be discussed and hopefully help further dream engineering to improve induction techniques.     

Visual awareness judgments are sensitive to accuracy feedback in stimulus discrimination tasks

In this study we tested the hypothesis that perceptual awareness judgments are sensitive to accuracy feedback about the previous action. We used a perceptual discrimination task in which participants reported their stimulus awareness. We created two conditions: No-feedback and Feedback (discrimination accuracy feedback was provided at the end of each trial). The results showed that visual awareness judgments are related to the accuracy of current and previous responses. Participants reported lower stimulus awareness for incorrectly versus correctly discriminated stimuli in both conditions; they also reported lower stimulus awareness in trials preceded by incorrect discrimination responses, compared to trials preceded by correct discrimination responses. This difference was significantly stronger in the Feedback condition, in which we also observed post-error slowing for PAS ratings. We discuss the relation between visual awareness and the effects of performance monitoring and interpret the results in the context of current theories of consciousness.