激活右腹外侧前额叶提高抑郁症患者对社会疼痛的情绪调节能力：一项TMS研究

负性人际交往经历和负性社会事件是抑郁症的重要诱导因素, 而社会功能受损是抑郁症患者的重要特征之一, 患者通常表现出对社会疼痛的情绪失调。为了提高抑郁症患者在负性社交情境中或面对负性社会事件时的情绪调节能力, 本研究采用经颅磁刺激技术(transcranial magnetic stimulation, TMS), 考察抑郁症患者在腹外侧前额叶(the ventrolateral prefrontal cortex, VLPFC)被激活后其情绪调节能力的改变。结果表明, 当右侧VLPFC被TMS激活且患者采用认知重评策略调节情绪时, 实验组患者(n = 64)比对照组患者(n = 63)在社会排斥情境下报告了更弱的负性情绪体验, 这说明激活右侧VLPFC可以有效提高患者对社会疼痛的外显性情绪调节能力。本研究是采用TMS提高抑郁症患者情绪调节能力的首次尝试, 实验发现不但支持了VLPFC与认知重评策略的因果关系, 还为临床改善抑郁症等社会功能障碍患者的情绪调节能力提供了明确的神经治疗靶点。后续研究还需探讨多疗程TMS刺激方案、改变社会疼痛的诱发方式、对比左右侧VLPFC的治疗效果、尝试使用其他的情绪调节策略, 进一步验证本研究的结论, 优化TMS治疗方案。     

背外侧前额叶对主动遗忘负性社会反馈的作用：针对抑郁症的TMS研究

抑郁症患者的负性心境可能源于其抑制功能障碍。患者在主动遗忘负性材料时无法有效调用背外侧前额叶(the dorsolateral prefrontal cortex, DLPFC)等负责抑制控制的额叶脑网络。同时, 患者对社会信息的加工比对非社会信息的加工存在更明显的认知神经障碍, 很难主动遗忘对自己不利的社会反馈信息。为了提高抑郁症患者对负性社会反馈的主动遗忘能力, 本研究采用经颅磁刺激技术(transcranial magnetic stimulation, TMS), 考察抑郁症患者在左侧(n = 32)或右侧DLPFC (n = 30)被激活后其记忆控制能力的改变。结果表明, 当患者的DLPFC被TMS激活时, 他们对社会拒绝的回忆正确率与健康对照组(n = 31)无差异, 且TMS激活右侧DLPFC还改善了患者对他人的社会态度。本研究是采用TMS提高抑郁症患者主动遗忘能力的首次尝试, 研究结果不但支持了DLPFC与记忆控制功能的因果关系, 还为临床治疗抑郁症、创伤后应激障碍、药物成瘾等患者的记忆控制缺陷提供了明确的神经靶点。     

被动性社交网站使用与青少年体像烦恼的关系:体像比较和体像自我差异的中介作用

为探讨被动性社交网站使用和青少年体像烦恼的关系,基于社会比较理论和自我差异理论,采用被动性社交网站使用问卷、社交网站体像比较量表、理想体像问卷和体像烦恼量表,对789名初、高中生进行调查。结果表明：（1）被动性社交网站使用对青少年体像烦恼具有显著的正向预测作用;（2）体像比较和体像自我差异能在被动性社交网站使用和体像烦恼的关系中起中介作用;（3）在被动性社交网站使用与体像烦恼的关系中,女生的体像比较和体像自我差异起并行中介作用,而对男生而言,体像比较和体像自我差异起链式中介作用。研究结果表明被动性社交网站使用不仅能直接影响青少年的体像烦恼,还可通过体像比较和体像自我差异的间接作用对青少年体像烦恼产生影响,且中介路径存在性别差异。     

大学生主观童年创伤症状对抑郁的影响:抗挫折能力和外向性的多重中介效应

本研究将"童年创伤"定义为"个体14岁以前所经历的,站在主体的角度主观感受到的创伤性事件"。采用问卷调查法对302名大学生进行调查,通过定量加定性的方式探索了童年创伤与抑郁之间的关系。相关分析表明：主观童年创伤症状、外向性、抗挫折能力、抑郁之间两两显著相关;结构方程模型表明：主观童年创伤症状通过外向性、抗挫折能力完全、多重中介作用间接预测抑郁。本研究结果在理论和实践层面对大学生抑郁问题的预防和干预工作提供重要的借鉴依据。     

Temporal coordination between maternal looming and infant gaze in depressed and nondepressed dyads: A bootstrapping approach

In this study, we examine the convergent validity of a measure of maternal looming derived using a motion capture system, and the temporal coordination between maternal loom and infant gaze using an event-based bootstrapping procedure. The sample comprised 26 mothers diagnosed with postpartum depression, 43 nondepressed mothers, and their 4-month-old infants. Mother-infant interactions were recorded during a standard face-to-face setting using video cameras and a motion capture system. First, results showed that maternal looming was correlated with a globally coded measure of maternal overriding. Maternal overriding is an intrusive behavior occurring when the mother re-directs the infant’s attention to parent-led activities. Thus, this result confirms that maternal looming can be considered a spatial intrusion in early interactions. Second, results showed that compared to nondepressed dyads, depressed dyads were more likely to coordinate maternal loom and infant gaze in a Loom-in-Gaze-pattern. We discuss the use of automated measurement for analyzing mother-infant interactions, and how the Loom-in-Gaze pattern can be interpreted as a disturbance in infant self-regulation.     

初中生亲子关系与抑郁:自尊和情绪弹性的中介作用

基于生态系统理论和认知易感性模型,本研究拟探讨初中生亲子关系对抑郁的影响及作用机制,采用问卷法对813名初中生进行调查。结果表明：（1）亲子关系、自尊、情绪弹性与抑郁之间呈两两显著相关,且亲子关系能显著负向预测抑郁;（2）自尊和情绪弹性在亲子关系与抑郁之间起显著的中介作用,具体包括三条路径：一是自尊的单独中介作用;二是情绪弹性的单独中介作用;三是自尊和情绪弹性的序列中介作用。本研究揭示了初中生亲子关系通过内在心理因素对抑郁水平产生影响的作用机制,为进一步提升初中生的心理健康提供了指导性建议。     

Interpersonal Psychotherapy—Adolescent Skills Training With Youth From Asian American and Immigrant Families: Cultural Considerations and Intervention Process

Although research has identified effective evidence-based depression prevention interventions for diverse youth, little is known about how the intervention process unfolds with immigrant family youth. This study utilized a qualitative approach to explore cultural and clinical differences in the implementation of Interpersonal Psychotherapy–Adolescent Skills Training (IPT-AST) in two schools, one serving youth from primarily immigrant, Asian American families and the second, youth from mostly nonimmigrant, non-Hispanic White families. A total of 131 IPT–AST sessions were audio recorded, transcribed, and coded for presence and patterns of cultural and clinical constructs. Results revealed that sessions with immigrant family youth were more likely to contain discussions of interpersonal problems characterized by estrangement, goals of spending time together with important others, mentions of emotion suppression and academic achievement expectations, conversations about acculturation, differences in value orientation, and discomfort with implementing new intervention skills. Dialogue from interventionist and youth exchanges is presented to illustrate how these themes emerged and were addressed by interventionists in a culturally responsive manner. The study highlights how IPT–AST with immigrant family and Asian American youth may unfold differently compared to youth from nonimmigrant families. Implications of findings for providers are discussed.     

父亲抑郁对幼儿问题行为的影响:教养效能感和教养方式的中介作用

以310名幼儿父亲为研究对象,采用流行病调查中心抑郁量表、父母教养能力感量表的教养效能感分问卷、父母教养方式评价量表和Conners儿童行为问卷,考察父亲教养效能感和教养方式在父亲抑郁与幼儿问题行为间的中介作用。结果显示:(1)父亲抑郁、专制粗暴、情感联系和幼儿问题行为两两之间均显著正相关,父亲教养效能感、民主关怀、宽容理解两两之间均显著正相关,父亲教养效能感、民主关怀、宽容理解分别与父亲抑郁、专制粗暴、情感联系和幼儿问题行为两两之间显著负相关;(2)父亲抑郁对幼儿问题行为具有显著的正向预测作用;(3)父亲教养效能感和自身的民主关怀、专制粗暴、情感联系不仅分别在父亲抑郁与幼儿问题行为之间起部分中介作用,而且在父亲抑郁与幼儿问题行为之间起链式中介作用。