SLE患者焦虑抑郁影响因素调查分析

为了探讨SLE（systemic lupus erythematosus）即系统性红斑狼疮患者焦虑抑郁心理影响因素,应用Zung焦虑自评量袁（Self—rating anxiety scale,SAS）和抑郁自评量表（self—rating depression scale,SDS）,对36例系统性红斑狼疮患者进行检测,辅以自行设计因素调查表进行相关因素调查。结果显示,SDS和SAS均分为49．70±11．3和42．13±8．9,与国内常模比较,差异有统计学意义,P〈0．01。单因素分析显示：对疾病的恐惧感、对病情了解程度、治疗效果、药物副作用、家庭经济状况、家庭支持、婚姻关系、睡眠质量、担心事业受影响、躯体症状的反复出现、社交娱乐活动受限、担心医护不精心12项因素与SLE患者抑郁焦虑状态的发生显著相关,P〈0．01。证明SLE患者抑郁焦虑心理与对疾病的恐惧感、治疗效果、家庭经济状况、睡眠质量等因素相关,这为心理干预提供了依据。     

In Spite of Indeterminacy Many Common Factor Score Estimates Yield an Identical Reproduced Covariance Matrix

It was investigated whether commonly used factor score estimates lead to the same reproduced covariance matrix of observed variables. This was achieved by means of Schönemann and Steiger’s (1976) regression component analysis, since it is possible to compute the reproduced covariance matrices of the regression components corresponding to different factor score estimates. It was shown that Thurstone’s, Ledermann’s, Bartlett’s, Anderson-Rubin’s, McDonald’s, Krijnen, Wansbeek, and Ten Berge’s, as well as Takeuchi, Yanai, and Mukherjee’s score estimates reproduce the same covariance matrix. In contrast, Harman’s ideal variables score estimates lead to a different reproduced covariance matrix.     

Sensitivity to local sentence context information in lexical ambiguity resolution: evidence from left- and right-hemisphere-damaged individuals

Using a cross-modal semantic priming paradigm, the present study investigated the ability of left-hemisphere-damaged (LHD) nonfluent aphasic, right-hemisphere-damaged (RHD) and non-brain-damaged (NBD) control subjects to use local sentence context information to resolve lexically ambiguous words. Critical sentences were manipulated such that they were either unbiased, or biased toward one of two meanings of sentence-final equibiased ambiguous words. Sentence primes were presented auditorily, followed after a short (0 ms) or long (750 ms) interstimulus interval (ISI) by the presentation of a first- or second-meaning related visual target, on which subjects made a lexical decision. At the short ISI, neither patient group appeared to be influenced by context, in sharp contrast to the performance of the NBD control subjects. LHD nonfluent aphasic subjects activated both meanings of ambiguous words regardless of context, whereas RHD subjects activated only the first meaning in unbiased and second-meaning biased contexts. At the long ISI, LHD nonfluent aphasic subjects failed to show evidence of activation of either meaning, while RHD individuals activated first meanings in unbiased contexts and contextually appropriate meanings in second-meaning biased contexts. These findings suggest that both left (LH) and right hemisphere (RH) damage lead to deficits in using local contextual information to complete the process of ambiguity resolution. LH damage seems to spare initial access to word meanings, but initially impairs the ability to use context and results in a faster than normal decay of lexical activation. RH damage appears to initially disrupt access to context, resulting in an over-reliance on frequency in the activation of ambiguous word meanings.     

Expect the Best and Prepare for the Worst: Anticipatory Coping and Preparations for Y2K

The Y2K Bug, the programming glitch expected to derail computerized systems worldwide when the year changed from 1999 to 2000, provided a rich context for examining anticipatory coping and preparatory behaviors. In the last 2 months of 1999, 697 respondents completed an online survey of proactivity, worry about Y2K, dispositional optimism, primary and secondary control-oriented coping efforts, estimates of Y2K-related disruptions, and household preparations. Higher levels of proactivity, worry, and optimism were independently associated with greater self-reported preparations. These predictors were positively associated with greater primary control-oriented coping efforts, but showed differential relations to secondary control efforts, such as accepting the situation or trusting a higher power, especially among participants who thought the damage would be severe and lasting. Implications for understanding multiple ways of coping with potential stressors are discussed.

Time ordering in frontal lobe patients: a stochastic model approach

Frontal lobe patients reproduced a sequence of capital letters or abstract shapes. Immediate and delayed reproduction trials allowed the analysis of short- and long-term memory for time order by means of suitable Markov chain stochastic models. Patients were as proficient as healthy subjects on the immediate reproduction trial, thus showing spared encoding and short-term memory. They failed, instead, on the delayed trials with capital letters, but not with random shapes, suggesting that their long-term memory impairment did not depend on primary deficits for ordering, but on inability to benefit from the organisational strategies that improve the retention and retrieval in normal subjects.     

Toward an understanding of aging in plutonium from direct measurements of stored energy

ABSTRACT

We present here the first direct measurement of the radiation-damage-induced energy stored in δ-phase plutonium. The primary mode of radioactive decay of ²³⁹Pu occurs with a time constant of τ=1.1?×?10¹²?s. Each decay imparts about 85?keV of recoil energy to the uranium byproduct, 5.2?Mev to the alpha particle, and a spectrum of mostly low energy gamma rays with the most probable at 51?keV [1]. Most of the decay energy is converted immediately to heat, releasing about 1.9?mW/g. However, some thermally-recoverable energy remains trapped. Reported here are measurements of that stored energy using differential scanning calorimetry (DSC) applied to ²³⁹Pu-2.0 at.%Ga δ-phase alloy. Retained energy of ～2 J/g saturates at about 5 months and is unchanged after 30 years. The magnitude of the stored energy agrees with a short-bond defect model that that we present here. This model treats radiation damage as a Pu impurity with shortened bond lengths. It explains the change in known properties with age and predicts that density increases with age, contrary to current thinking. The short-bond impurities proposed are expected to act like other impurities, affecting strength, phase transitions, grain boundaries and other metallurgical properties.     

Investigation of the interaction of He and D in FeBSi alloy

He and H can be produced by nuclear reaction. In addition, energetic particles of He and T and D, which are isotopes of H, in the plasma of fusion reactor induce the damage in the surface of materials, such as erosion, sputtering and blistering. To investigate the interaction of He and D, amorphous and crystalline FeBSi alloys were irradiated by He or D₂ or He?+?D₂ ions with 5?keV. The results of thermal desorption indicated that more He atoms were trapped in both the amorphous and crystalline alloy irradiated by He ions than D atoms in those alloys irradiated by D₂ ions. Although He and D atoms were trapped in FeBSi alloy irradiated by He?+?D₂ ions, desorption peaks of D₂ and He were separated. Absorption of D in an amorphous alloy was influenced by the presence of He; however, absorption of He was independent of D₂ irradiation in both alloys.     

骨髓捐献人中途拒捐的民事责任探析——基于信赖保护的视角

基于捐献行为的公益性、单务性和人身性,各国法律赋予捐献人任意撤销权,但是出于对捐献人允诺的信赖而改变自身处境的接受人利益也应该得到保护.从信赖保护的视角出发,在血型高分辨检测之前,捐献人一旦签订了捐献协议,即负有保护接受人信赖利益的义务,捐献人虽然有权中途拒捐,但应当承担信赖赔偿责任.     

The effects of stress on dna repair capacity

Abstract

Research has shown that lymphocytes of high-distress patients have reduced DNA repair relative to that of low-distress patients and healthy controls. Furthermore, deficits in repair are associated with an increased risk of cancer. Using and academic stress model, we hypothesized that students would exhibit lower levels of Nucleotide Excision Repair (NER) during a stressful exam period when compared to a lower stress period. Participants were 19 healthy graduate level students. NER was measured in lymphocytes using the unscheduled DNA synthesis (UDS) assay with slide autoradiography. Contrary to prediction, mean values for NER significantly increased during the higher stress period relative to the lower stress period controlling for background differences in repair. Furthermore, lymphocytes had significantly increased repair of endogenous damage during the higher stress period. Stress appears to directly increase DNA repair. Additionally, stress may increase DNA repair indirectly by increasing damage to DNA.     

Percentile Norms and Accompanying Interval Estimates from an Australian General Adult Population Sample for Self‐Report Mood Scales (BAI,BDI, CRSD,CES‐D,DASS, DASS‐21, STAI‐X,STAI‐Y,SRDS, and SRAS)

Despite their widespread use, many self‐report mood scales have very limited normative data. To rectify this, Crawford et al. have recently provided percentile norms for a series of self‐report scales. The present study aimed to extend the work of Crawford et al. by providing percentile norms for additional mood scales based on samples drawn from the general Australian adult population. Participants completed a series of self‐report mood scales. The resultant normative data were incorporated into a computer programme that provides point and interval estimates of the percentile ranks corresponding to raw scores for each of the scales. The programme can be used to obtain point and interval estimates of the percentile ranks of an individual's raw scores on the Beck Anxiety Inventory, the Beck Depression Inventory, the Carroll Rating Scale for Depression, the Centre for Epidemiological Studies Rating Scale for Depression, the Depression, Anxiety, and Stress Scales (DASS), the short‐form version of the DASS (DASS‐21), the Self‐rating Scale for Anxiety, the Self‐rating Scale for Depression, the State–Trait Anxiety Inventory (STAI), form X, and the STAI, form Y, based on normative sample sizes ranging from 497 to 769. The interval estimates can be obtained using either classical or Bayesian methods as preferred. The programme (which can be downloaded at http://www.abdn.ac.uk/~psy086/dept/MoodScore_Aus.htm ) provides a convenient and reliable means of obtaining the percentile ranks of individuals' raw scores on self‐report mood scales.