Impact of series length on statistical precision and sensitivity of autocorrelation assessment in human locomotion

Long-range autocorrelations (LRA) are a robust feature of rhythmic movements, which may provide important information about neural control and potentially constitute a powerful marker of dysfunction. A clear difficulty associated with the assessment of LRA is that it requires a large number of cycles to generate reliable results. Here we investigate how series length impacts the reliability of LRA assessment. A total of 94 time series extracted from walking or cycling tasks were re-assessed with series length varying from 64 to 512 data points. LRA were assessed using an approach combining the rescaled range analysis or the detrended fluctuation analysis (Hurst exponent, H), along with the shape of the power spectral density (α exponent). The statistical precision was defined as the ability to obtain estimates for H and α that are consistent with their theoretical relationship, irrespective of the series length. The sensitivity consisted of testing whether significant differences between experimental conditions found in the original studies when considering 512 data points persisted with shorter series. We also investigate the use of evenly-spaced diffusion plots as a methodological improvement of original version of methods for short series. Our results show that the reliable assessment of LRA requires 512 data points, or no shorter than 256 data points provided that more robust methods are considered such as the evenly-spaced algorithms. Such series can be reasonably obtained in clinical populations with moderate, or even more severe, gait impairments and open the perspective to extend the use of LRA assessment as a marker of gait stability applicable to a broad range of locomotor disorders.     

Governing sporting brains: concussion,neuroscience, and the biopolitical regulation of sport

Abstract

Drawing on the recent concussion litigation from the United States’ National Football League (NFL), the paper examines the emergence of neuroscience knowledge as part of a defining rationale for the justification and rationalization of the lawsuit. The paper argues that neuroscience knowledge is best understood as a regulatory discourse that is attached to larger social, political, and economic realities that bring it into being as a legitimate type of knowledge. This larger socio-political governance logic is one that scholars call ‘biopolitical’ which emphasizes the protection of individual life over and above other ways of being. Risk discourses that frame risk-taking practices as immoral thus emerge within this biopolitical regime of governance that frame morality in terms of public health that individual citizens ought to pursue. With this in mind neuroscience knowledge plays an important role in concussion litigation. It emerges as a technology of biopolitical governance in that it is used to justify legal decisions on concussion. This is despite the fact that neuroscience knowledge remains nascent and even scientifically uncertain. Because of this, the paper argues that scholars ought to not only consider neuroscience research skeptically, but also ought to be aware of the dangers of neuroscience’s emergence as an ‘anticipatory discourse’ that has the potential to reduce human behavior to matters of the brain that thus transforms our very ontology of ourselves and the practices we perceive as ‘good’.     

Reinforcing staying and switching while using a changeover delay

Performance on concurrent schedules can be decomposed to run lengths (the number of responses before switching alternatives), or visit durations (time at an alternative before switching alternatives), that are a function of the ratio of the rates of reinforcement for staying and switching. From this analysis, a model of concurrent performance was developed and examined in two experiments. The first exposed rats to variable-interval schedules for staying and for switching, which included a changeover delay for reinforcers following a switch. With the changeover delay, run lengths and visit durations were functions of the ratios of the rates of reinforcement for staying and for switching, as found by previous research not using a changeover delay. The second directly assessed the effect of a changeover delay on run lengths and visit durations. Each component of a multiple schedule consisted of equivalent stay and switch schedules but only one component included a changeover delay. Run lengths and visit durations were longer when a changeover delay was used. Because visit duration is the reciprocal of changeover rate, these results are consistent with the established finding that a changeover delay reduces the frequency of switching. Together these results support the local model of concurrent performance as an alternative to the generalized matching law as a model of concurrent performance. The local model may be preferred when accounting for more molecular aspects of concurrent performance.     

Advances in Behaviorism: It's Not What It Used to Be

Behaviorism has changed over the past half century and its modern form is not familiar to many educators and other applied professionals. Put briefly, behaviorism has changed from the molecular and absolutist form of years past, when basic researchers, therapists and educators sought to modify isolated target behaviors. Modern behaviorism is relativistic and molar and the articles included in this issue are meant to illustrate this changed emphasis. The first article shows how the matching law has redefined the old law of effect and how that affects application. The second shows how relational frames provide a behavioral treatment of cognitive variables that dispels the stereotyped view of behavior modification. The third treats molar classes of behaviors as traits, and individual behaviors as states, applying that distinction to aspects of the relative frequencies of behaviors of children at home and at school. Finally, the last article shows specifically how behavioral methods have been (and are) applied to the behavior of autistic children, in a program that has been extremely successful over the past few years.     

Masked ball: Ethics,laws and financial contradictions in hungarian health care

Corruption is a major problem in the societies of the post-communist Central European countries. Corruption in health care has some unique characteristics undermining the efficacy of and respect for Hungarian health care. One of the forms of corruption is tipping. This highly contested phenomenon is present in most of the patient/health professional’s interactions in a sophisticated manner, raising serious ethical and legal dilemmas. The present paper analyzes tipping and other corruption-related factors, such as financial conflict of interest between industry and health care and argues that since ethical and legal considerations are often ignored in the country, patient care and clinical research are affected by these controversial issues to a great extent.     

James Drane's More Humane Medicine: a new foundation for twenty-first century bioethics?

James Drane's More Humane Medicine: A Liberal Catholic Bioethics is an outstanding contribution to the study of bioethics in our day. Catholics and others who are interested in the issues discussed here will benefit from this masterful treatment. The author opens with a set of definitions, starting with what he means by a "more humane medicine." Drane contends that a more humane medicine has become necessary and desired, but not because the traditional medical ethic as "a self-declared and self-imposed ethic, outlining what noble service to others entails" is no longer valid. Rather he defines it as an advance on the traditional ethic; a "new foundation" based on a "lived set of obligations derived from a felt commitment to other persons ... an ethics based on the relationship between doctors and patients and essentially an ethics of virtue." Drane's work is a "liberal Catholic Bioethics" in which he challenges his own faith tradition, the Roman Catholic Church, on such topics as sexuality, birth control, abortion, cloning, stem cell research, aging and dying, and euthanasia and physician-assisted suicide. The present article is a critical essay that analyzes the author's statements and conclusions.     

E Contrario Reasoning: The Dilemma of the Silent Legislator

Summary This contribution offers an evaluation of e contrario reasoning in which the interpretation of a legal rule is based on the context of the law system (contextual e contrario reasoning). A model is presented which will show all the explicit and implicit elements of the argument at work and will also point out how these distinct parts are interrelated. By questioning the content and justificatory power of these elements, the weak spots in the argument can be laid bare. It will be argued that e contrario reasoning inevitably requires a dubious argumentative step, which renders the argument intrinsically weak. The model is applied to a European lawsuit on French cheese.     

Reconstructing Complex Analogy Argumentation in Judicial Decisions: A Pragma-Dialectical Perspective

Empirical research in the field of legal interpretation shows that, in many cases, analogy argumentation is complex rather than simple. Traditional analytical approaches to analogy argumentation do not explore that complexity. In most cases analogy argumentation is reconstructed as a simple form of argumentation that consists of two premises and a conclusion. This article focuses on the question of how to analyze and evaluate complex analogy argumentation. It is shown how the pragma-dialectical approach provides clues for analyzing complex analogy argumentation and how the criteria for evaluating analogy argumentation can be used to reconstruct these types of complex analogy argumentation in Dutch case law. The critical questions in the argumentation scheme do not only serve as a tool for analyzing arguments justifying analogy argumentation, but are also helpful in analyzing arguments against a specific analogy argumentation.