Tolerance to effects of cocaine on behavior under a response-initiated fixed-interval schedule

Tolerance to effects of cocaine can be modulated by schedules of reinforcement. With multiple ratio schedules, research has shown an inverse relationship between ratio requirement and amount of tolerance that resulted from daily administration of the drug. In contrast, tolerance to the effects of cocaine on behavior under multiple interval schedules generally has developed regardless of interval value. Under interval schedules reinforcement depends on the animal making one response following a time interval. Thus, as time to respond increases, the time to reinforcement decreases. On the other hand, fixed ratio schedules require a specified number of responses to be made prior to reinforcement. Therefore, delaying the initiation of responding does not coincide with a significant decrease in the time to reinforcement. In the current experiment, 6 pigeons were trained to respond under a three-component multiple schedule, with a different tandem fixed-ratio 1 fixed-interval schedule in each component. The multiple schedule required one response, which was followed by one of three fixed-interval values (5, 15, or 60 s). Thus, the multiple schedule was interval-like because after the fixed-ratio 1, only one more response was required for reinforcement, but it was also ratio-like because the length of the pause at the beginning of each interreinforcer interval affected the time until the next reinforcer. Acute administration of cocaine generally resulted in dose-dependent decreases in responding. Chronic (i.e., daily) administration of a rate-decreasing dose resulted in tolerance patterns similar to those usually obtained with multiple ratio schedules. That is, the magnitude of tolerance was related inversely to schedule size. These results suggest that delay to reinforcement from the initial response may play a role in the development of schedule-parameter-related tolerance.     

Tolerance or Hospitality?

Facing the development of pluralistic cultures and the conflict of varied civilizations, we should examine political theory frameworks, particularly as concerns the construction of world order. On the problem of “tolerance or hospitality,” tolerance has been the target of opposition. Jacques Derrida deconstructs this concept and supports Immanuel Kant’s notion of hospitality instead of tolerance. However, Jürgen Habermas advocates reconstructing the concept of tolerance, although he does note its limits. We should regard hospitality as the fundamental spirit of international relations and take the notion of “Seeking Sameness and Respecting Diversity” as a principle for handling relations between different cultures.     

不确定性容忍度对风险偏好的影响及其情景依赖性

研究以经营店面为背景设计决策材料,采用2(不确定性容忍度:高/低)×2(损益背景:损失/获益)×2(选项描述框架:积极/消极)×3(损益概率:高/中/低)混合实验设计,探讨不同任务情景下个体不确定性容忍度对风险偏好的影响。结果发现,不确定性容忍度主效应显著,高容忍度者比低容忍度者更冒险。不确定性容忍度与损益背景交互作用显著：在损失背景下,高容忍度者比低容忍度者更冒险,在获益背景下无此效应。不确定性容忍度与选项描述框架交互作用显著：在积极框架下,高容忍度者比低容忍度者更冒险,在消极框架下无此效应。这表明,不确定性容忍度对风险偏好产生影响,但这种影响会受到损益背景和选项描述框架的调节,具有情景依赖性。     

At‐one‐ment,intuition and ‘suchness’1

Many senses exist for perceiving sensory experience; there are in turn others which make it possible to perceive emotional experience: intuition is one of these. The author, using W. R. Bion's work, studies intuition psychoanalytically, considering it to be a powerful ‘sense’ in clinical work. He describes the metapsychology of intuition, and proposes models that make it possible to think—from different perspectives— about how to make use of it in an analysis. To this end, he examines a series of useful processes and concepts: growth, tolerance, ‘suchness’, suffering and courage. The author defi nes the intuitive mechanism as a derivation of the renunciation of memory, desire and understanding; such a renunciation, learning from the experience of suffering the pain of facing the Truth in at‐one‐ment, makes it possible to tolerate the frustrations associated with observing the analysand ‘such‐as‐he‐is’. Finally, once immersed in the intelligence of intuition, the author considers ways in which intuition might be linked with concepts, with a view to interpreting the facts that must be transformed in the analysis.     

Prior self-control exertion and perceptions of pain during a physically demanding task

ObjectivesExertion of self-control has been associated with impaired performance on subsequent physical tasks also requiring self-control, but it remains unknown why this occurs. This study, therefore, explored whether a) prior self-control exertion reduces subsequent persistence on a physically demanding task, and b) whether any observed performance decrements could be explained by changes in perceptions of pain.MethodIn a within-subject design, sixty-three individuals completed an easy (congruent) Stroop task or a difficult (incongruent) Stroop task that required self-control. Participants were then required to remain in a physically demanding posture (i.e., a ‘wall-sit’) until voluntary exhaustion and their perception of pain was recorded during the task.ResultsWhen participants completed the difficult Stroop task, they quit the wall-sit sooner. This decrement in performance was explained by greater perceptions of pain at the beginning of the wall-sit.ConclusionsPerceptions of pain may, therefore, be an important attentional mechanism explaining why self-control use interferes with subsequent persistence during physically effortful tasks.     

Examining the specific dimensions of distress tolerance that prospectively predict perceived stress

We examined five dimensions of distress tolerance (i.e. uncertainty, ambiguity, frustration, negative emotion, physical discomfort) as prospective predictors of perceived stress. Undergraduate students (N = 135) completed self-report questionnaires over the course of two assessment sessions (T1 and T2). Results of a linear regression in which the five dimensions of distress tolerance and covariates (i.e. T1 perceived stress, duration between T1 and T2) served as predictor variables and T2 perceived stress served as the outcome variable showed that intolerance of uncertainty was the only dimension of distress tolerance to predict T2 perceived stress. To better understand this prospective association, we conducted a post hoc analysis simultaneously regressing two subdimensions of intolerance of uncertainty on T2 perceived stress. The subdimension representing beliefs that “uncertainty has negative behavioral and self-referent implications” significantly predicted T2 perceived stress, while the subdimension indicating that “uncertainty is unfair and spoils everything” did not. Results support a growing body of research suggesting intolerance of uncertainty as a risk factor for a wide variety of maladaptive psychological outcomes. Clinical implications will be discussed.     

睡眠剥夺影响风险决策的双系统模型探讨

睡眠剥夺是指由于环境或自身原因无法满足正常睡眠时间的情况。大量实证研究发现, 睡眠剥夺会导致个体在风险决策中更倾向于风险寻求, 同时也有研究表明睡眠剥夺会导致个体风险规避, 而目前尚无统一结论。睡眠剥夺从风险感知、风险容忍、风险决策策略三个方面影响了风险决策, 其心理机制可由认知和情绪双路径模型进行解释, 且脑神经生理学研究也提供了相关证据。未来的研究应该进一步关注：(1)现实工作生活中的睡眠不足对风险决策的影响; (2)睡眠剥夺影响风险决策的理论模型建构。     

Intellectual humility and religious tolerance

Abstract

The present study explored the relationship between (a) intellectual humility toward religious beliefs and values and (b) religious tolerance. Pastors who identified as Christian (N = 196) completed measures of conservatism, religious commitment, intellectual humility toward religious beliefs and values, and religious tolerance. Intellectual humility was a positive predictor of religious tolerance, even when controlling for conservatism and religious commitment. An interaction was found between exposure to religious diversity and intellectual humility, such that exposure to religious diversity was positively related to religious tolerance only for participants who reported high levels of intellectual humility. We conclude by discussing limitations, areas for future research, and implications for interfaith dialog and engagement.     

Effects of acute and chronic flunitrazepam on delay discounting in pigeons

Delay to delivery of a reinforcer can decrease responding for that reinforcer and increase responding for smaller reinforcers that are available concurrently and delivered without delay; acute administration of drugs can alter responding for large, delayed reinforcers, although the impact of chronic treatment on delay discounting is not well understood. In this experiment, the effects of repeated administration of the benzodiazepine flunitrazepam were studied in 6 pigeons responding on one key to receive food that was delivered immediately and on a second key to receive a larger amount of food that was delivered following delays which increased across a single session. Pigeons responded predominantly for the large reinforcer when there were no delays and when delays were short; however, as delays increased, responding for the large reinforcer decreased. Acutely, flunitrazepam (0.32, 1.0 and 3.2 mg/kg) dose-dependently increased responding for the large reinforcer, shifting the discounting curve rightward and upward. Repeated administration of flunitrazepam (0.32, 1.0 and 3.2 mg/kg, each for six sessions, separated by one session during which vehicle was administered) did not markedly alter its effects on responding for the large reinforcer, indicating that the development of tolerance to this effect of flunitrazepam is modest under these conditions.